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Toxicologia 2p > Fosfina y fosfuros. > Flashcards

Fosfina y fosfuros. Flashcards

1
Q

Que es la fosfina

A

PH3
Gas incoloro con olor a pes flamable
2ppm

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2
Q

Que es el fosfuro de aluminio

A

AIP

Polvo gris oscuro.

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3
Q

Que es el fosfuro de calcio

A

Ca3P2

Rojo cafe

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4
Q

Que es el fosfuro de ZINC

A

Zn3P2

Gris oscuro

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5
Q

Cual es el mecanismo de a. de la fosfina

A

Accion de bloqueo de citrocromo C en organos que consumen mucho O2

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6
Q

Intoxicacion aguda de la fosfina MC en vias respiratorias

A

Irritacion, tos,expectoracion, opresion,disnea,dificultad respiratoria,edema pulmonar,ARDS

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7
Q

Intoxicacion aguda de la fosfina MC en via Cardiovascular.

A

Taquicardia, hipotension,choque

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8
Q

Intoxicacion aguda de la fosfina MC en via Neurologica

A

Mareo,cefalea,fatiga,estupor,ataxia,convulsiones y coma

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9
Q

Intoxicacion aguda de la fosfina MC en via gastrointestinal

A

Vomito,dolor y diarrea.

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10
Q

Intoxicacion aguda de la fosfina MC en via Higado

A

Ictericia,Insuf hepatica.

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11
Q

Intoxicacion aguda de la fosfina MC en via Riñon

A

Necrosis tubular, insuficiencia renal.

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12
Q

Intoxicacion aguda de la fosfina MC en via metabolico

A

Acidosis,hipo o hipermagnesemia, hipopotasemia.

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13
Q

Intoxicacion aguda de la fosfina MC en via Piel

A

Sudor,cianosis, dolor muscular, agitacion psicomotra

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14
Q

Caracteristicas de importancia toxicologica de fosfuro de Zinc

A 
Es soluble en agua 
Raticida
Flamable al contacto con acidos
Polvo gris oscuro cristalino.
Zinc produce vomitos
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15
Q

Dosis letal 50 de F. de Z

A

Humano oral 80mg/kg

Humano respiratorio 1000ppm/5 min

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16
Q

Toxicidad en humanos de F.de Z

A

4-5ml adultos

17
Q

Patologia de F de z

A

Muerte rapida: Edema pulmonar y cerebral

Sobrevivientes : Necrosis hepatica tubular, hemorragias en mucosas y derrames.

18
Q

Cuadro clinico de fosfuro de z

A 
Agitacion
Hipotension
Choque
Bloqueos cardiacos 
Arritmias 
Nausea
Vomito
Dolor abdominal 
Diarrea 
Cianosis
Opresion toracica
Edema pulmonar
Miocardiopatia
Falla renal 
Falla hepatica.
19
Q

Tx para forfuro de Z

A 
No emesis
Lavado G puede ser peligroso
Omeprazol
Permanganato de potasio 1:5000
No hay tratamiento especifico.
Tx de sosten.
20
Q

Tx de sosten de fosfuro de Z

A 
Corregir acidosis metabolica con HCO3.
Corregir alteraciones electrolica
Hipotension y choque 
Monitorear funcion renal y hepatica
Convulsiones: Dicepam Fenobarbital DFH
Ventilacion mecanica

Toxicologia 2p (7 decks)

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