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endocrine > Formative Questions > Flashcards

Formative Questions Flashcards

1
Q

A patient with Hypothyroidism would demonstrate which of the following symptoms:

  1. Exopthalmus
  2. Increased Heart Rate
  3. Heat Tolerance
  4. Increased Protein Catabolism
  5. Lethargy
A
  1. Lethargy
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2
Q

Goitre is a common symptom of thyroid dysfunction and can present in both hypo- and hyper-thyroidism. However it would not be present in which of the following thyroid pathologies?

  1. Primary Hypothyroidism
  2. Secondary Hypothyroidism
  3. Primary Hyperthyroidism
  4. Secondary Hyperthyroidism
  5. Grave’s Disease
A
  1. Secondary Hypothyroidism
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3
Q

A decrease in circulating cortisol levels would result in which of the following physiological responses:

  1. Enhanced gluconeogenesis in the liver
  2. Hypotension
  3. Decreased ACTH secretion from the anterior pituitary
  4. Elevated fatty acid levels in the plasma
  5. Suppression of the immune system
A
  1. Hypotension
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4
Q

A person with primary hypercortisolism would demonstrate:

  1. Depressed ACTH
  2. Elevated CRH
  3. Hypotension
  4. Hypoglycaemia
  5. Increased Bone Density
A
  1. Depressed ACTH
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5
Q

Chronic glucocorticoid therapy is associated with which of the following:

  1. Enhanced cortisol release from the adrenal glands
  2. Enhanced ACTH release from the anterior pituitary
  3. Enhanced CRH release from the hypothalamus
  4. Adrenal insufficiency
  5. Adrenal hypertrophy
A
  1. Adrenal insufficiency
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6
Q

Which of the following will elevate free calcium levels in plasma?

  1. Alkalosis
  2. Activation of osteoblasts
  3. Increased phosphate excretion at the kidney
  4. Calcitonin
  5. All of the above
A
  1. Increased phosphate excretion at the kidney
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7
Q

Regarding GH which of the following is correct?

  1. It is also known as somatostatin
  2. It is also known as somatomedian
  3. It is a steroid hormone
  4. Levels in adults are at their highest during REM sleep
  5. It is relatively insignificant in terms of foetal and neonatal growth
A
  1. It is relatively insignificant in terms of foetal and neonatal growth
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8
Q

The adrenal zona glomerulosa secreted which hormone:

  1. Testosterone
  2. Progesterone
  3. Aldosterone
  4. Cortisol
  5. Epinephrine/Adrenaline
A
  1. Aldosterone
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9
Q

Which of the following responses would you expect following insulin release:

  1. Hepatic gluconeogenesis
  2. Increased ketone formation
  3. Increased uptake of glucose by the brain
  4. Adipose lipolysis
  5. Stimulation of Na+/K+ ATPase
A
  1. Stimulation of Na+/K+ ATPase
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10
Q

Which of the following is not a Glucose Counter Regulatory Hormone:

  1. Thyroid Hormone
  2. Epinephrine (Adrenaline)
  3. Glucagon
  4. Cortisol
  5. Growth Hormone
A
  1. Thyroid Hormone
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11
Q

A 21 y/o man is diagnosed with T1DM. He is studying engineering at university and has a part-time as a delivery driver. He had just got married and his wife is expecting their first child. What information should he receive shortly after diagnosis?

  1. He should be told he cannot continue his driving job in the future
  2. He may be able to work off-shore depending on his employer and where he is going
  3. He is likely to pass on his diabetes to his child
  4. He should be advised to stop drinking any alcohol
  5. He should be told he is unlikely to ever have any hypos (hypoglycaemic episodes) if he monitors his blood glucose regularly
A
  1. He may be able to work off-shore depending on his employer and where he is going
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12
Q

It is advisable for everyone to pursue a healthy lifestyle if he/she wishes to reduce the risks of long term illness. Which of the following would be considered appropriated to tell a sedentary man with an unhealthy diet who is keen to change to a more healthy lifestyle?

  1. Aim for 150 minutes of moderate intensity physical activity per week
  2. Aim to eat 5 portions of fruit/vegetables per day
  3. Aim to eat 1 portion of oily fish per week
  4. It is inadvisable to drink more than 14 units of alcohol per week
  5. All of the above
A
  1. All of the above
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13
Q

53 y/o man diagnosed with T2DM 6 Months ago. He has lost 1 stone in weight his BMI is 28 and HbA1c is 75 mol/mol (9%). What is the next appropriate medication in his management?

  1. Insulin
  2. Thiazoldinedione (e.g. pioglitazone)
  3. Sulphonylurea (e.g. glimepiride)
  4. Biguanide (e.g. metformin)
  5. DPP IV inhibitor (e.g. sitagliptin)
A
  1. Biguanide (e.g. metformin)
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14
Q

Which symptom below is NOT typical of hypoglycaemia?

  1. Headache
  2. Itch
  3. Poor Concentration
  4. Sweating
  5. Irritability
A
  1. Itch
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15
Q

32 y/o patient with T1DM is reviewed at the diabetes clinic. His blood sugar is 3.2 mmol/l and he tells you he is feeling well. What is the best course of action next?

  1. Administer IM glucagon
  2. Send him home for lunch
  3. Give 200ml fresh orange juice
  4. Give digestive biscuit
  5. Administer his lunchtime insulin
A
  1. Give 200ml fresh orange juice
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16
Q

25 y/o with T1DM presents with vomiting and diarrhoea. BP 80/54 and RR is 24 breath/min. Which test is least important for immediate management?

  1. Blood Glucose
  2. pH
  3. Urine/Blood Ketones
  4. Electrolytes
  5. Liver Function Tests
A
  1. Liver Function Tests - exception if jaundiced
17
Q

23 y/o man diagnosed with hyperthyroidism and has been commenced on carbimazole. What do you need ti counsel him regarding?

  1. Neutropenia
  2. Fertility
  3. Metallic taste in the mouth
  4. Renal Function
  5. Discolouration of urine
A
  1. Neutropenia - Low WBCs
18
Q

A man with large prolactinoma complains of impaired vision. What is the most likely pattern of visual field loss to be found on clinical confrontation?

  1. Homonymous hemianopia
  2. Bitemporal hemianopia
  3. Total loss of vision in one eye
  4. Homonymous quadrantanopia
  5. Nasal hemianopia
A
  1. Bitemporal hemianopia
19
Q

38 y/o lady presents feeling tired and dizzy. She is tanned and her investigation show Na 123 (low) K 5.6 (high). Thyroid function tests are normal and calcium is normal. Her cortisol 50 (low). What is her diagnosis?

  1. Hyperparathyroidism
  2. Addison’s disease
  3. Cushing’s disease
  4. Grave’s disease
  5. Conn’s syndrome
A
  1. Addison’s disease
20
Q

All the condition below are well recognised causes of secondary diabetes except one. Which condition is not a recognised cause of secondary diabetes?

  1. Acromegaly
  2. Haemochromatosis
  3. Addison’s Disease
  4. Cushing’s Disease
  5. Chronic Pancreatitis
A
  1. Addisons Disease - issues w/ hypoglycaemia

endocrine (25 decks)

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