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alcohol > Formative > Flashcards

Formative Flashcards

1
Q

Antabuse - a drug used to treat alcoholism work by inhibiting

Select one:

a. alcohol phosphatase
b. alkaline phosphatase
c. aldehyde dehydrogenase
d. aldehyde phosphatase
e. alcohol dehydrogenase

A

Aldehyde dehydrogenase

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2
Q

Acute pancreatitis is associated with

Select one:

a. opiate use
b. diuretics
c. 2nd generation cefalosporins
d. 3rd generation cefalosporins
e. steroid use

A

Steroid use

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3
Q

Alcohol is associated with

Select one:

a. an accumulation of lipid in hepatocytes Correct
b. an increased number of plasma cells in portal areas
c. granulomas surrounding bile ducts
d. vascular congestion in portal tracts
e. an accumulation of iron in hepatocytes

A

An accumulation of lipid in hepatocytes

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4
Q

The legal age of drinking alcohol whilst at supervised at home is

Select one:

a. 5
b. 16
c. 18
d. 10
e. 15

A

5

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5
Q

The liver is divided into

Select one:

a. 3 segments
b. 8 segments
c. 9 segments
d. 5 segments
e. 2 segments

A

8

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6
Q

The recommended number of units of alcohol for a man in one week is

Select one:

a. 18 units
b. 16 units
c. 20 units
d. 14 units
e. 21 units

A

14

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7
Q

The respiratory center of the brain lies within the

Select one:

a. brainstem
b. cerebellum
c. frontal cortex
d. thalamus
e. occipital cortex

A

Brainstem

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8
Q

Persistent vomiting causing a gastric tear is known as a

Select one:

a. Watermelon stomach
b. Hypertensive portal gastropathy
c. GAVE - gastric antral vascular ectasia
d. Mallory Weiss tear Correct
e. Boerrhave syndrome

A

Mallory weiss tear

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9
Q

Portal hypertension is most associated with

Select one:

a. hepatomegaly
b. positive Murphy’s sign
c. positive Courvoisier’s sign
d. splenomegaly
e. Cullen’s sign

A

Splenomegaly

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10
Q

A patient with LFTs showing a normal GGT, AST and ALT with high Alk Phos is most likely to have

Select one:

a. pulmonary disease
b. viral hepatitis
c. recently drunk significant amounts of alcohol (binge drinking)
d. chronic alcoholism
e. bone disease

A

Bone disease

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11
Q

In general, females become intoxicated more rapidly than males because

Select one:

a. they tend to have a higher BMI
b. they are less accustomed to drinking
c. they consume different types of alcohol
d. they tend to have less alcohol dehydrogenase
e. they tend to have smaller livers

A

Tend to have less alcohol dehydrogenase

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12
Q

Which nerve supplies the heart?

Select one:

a. phrenic
b. accessory
c. cephalic
d. vagus
e. azygous

A

Vagus

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13
Q

Which of these microscopic features is NOT present within a portal tract?

Select one:

a. hepatocyte
b. bile duct
c. vein
d. artery
e. lymphocyte

A

Hepatocyte

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14
Q

Persistent vomiting may result in

Select one:

a. metabolic alkalosis
b. metabolic acidosis
c. respiratory acidosis
d. net normal pH
e. respiratory alkalosis

A

Metabolic alkalosis

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15
Q

A patient with haematemesis may suffer from

Select one:

a. neurogenic shock
b. cardiogenic shock
c. septic shock
d. hypovolaemic shock
e. anaphylactic shock

A

Hypovolaemic shock

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16
Q

The recommended number of units of alcohol for a woman in one week is

Select one:

a. 18 units
b. 14 units
c. 16 units
d. 21 units
e. 20 units

A

14

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17
Q

In a restaurant today a standard glass of wine (175mls) is likely to contain approximately

Select one:

a. 3 units of alcohol
b. 1 unit of alcohol
c. 1.5 units of alcohol
d. 2 units of alcohol
e. 0.5 units of alcohol

A

2 units

18
Q

After use of muscle glycogen the liver can produce “new glucose” through

Select one:

a. gluconeogenesis
b. glycophosphorylation
c. glycogenolysis
d. glucogenolysis
e. glyconeogenesis

A

Gluconeogenesis

19
Q

Which of these speeds up the elimination of alcohol form the body

Select one:

a. all of the above
b. water consumption
c. caffeine consumption
d. glucose solution
e. none of the above

A

None of the above

20
Q

Which of the following clinical signs can be associated with alcohol?

Select one:

a. Caput medusa
b. Kayser Fleischer ring
c. Roth spots
d. Janeway lesions
e. corneal arcus

A

Caput medusa

21
Q

Alcohol is initially metabolised by

Select one:

a. fumarate hydratase
b. cytochrome p450
c. alcohol hydratase
d. alcohol dehydrogenase
e. alcohol phosphatase

A

Alcohol dehydrogenase

22
Q

Jaundice as a result of alcoholic hepatitis is caused by an accumulation of

Select one:

a. conjugated biliverdin
b. unconjugated bilirubin
c. conjugated bilirubin
d. haptoglobin
e. unconjugated biliverdin

A

Conjugated bilirubin

23
Q

Chronic alcoholism is associated with

Select one:

a. reactive pericarditis
b. restrictive cardiomyopathy
c. hypertrophic cardiomyopathy
d. dilated cardiomyopathy
e. arrhythmogenic right ventricular dysplasia

A

Dilated cardiomyopathy

24
Q

Alcohol confers the strongest risk for

Select one:

a. oesophageal squamous cell carcinoma
b. hepatocellular carcinoma
c. pulmonary squamous cell carcinoma
d. colorectal adenocarcinoma
e. pulmonary adenocarcinoma

A

Hepatocellular carcinoma

25
Q

The ligamentum teres within the falciform ligament is formed from which embryological structure?

Select one:

a. mesonephric duct
b. umbilical vein
c. umbilical artery
d. urachus
e. vitelline duct

A

Umbillical vein

26
Q

The term “inotrope” refers to

Select one:

a. cardiac rate
b. ventricular filling volume
c. total peripheral resistance
d. cardiac contractility
e. atrial filling volume

A

Cardiac contractility

27
Q

Severe hepatitis is associated with

Select one:

a. hepatoreticular syndrome
b. hepatorenal syndrome
c. hepatorespiratory syndrome
d. hepatocardiac syndrome
e. hepatobiliary syndrome

A

Hepatorenal

28
Q

The liver enzyme ALT is short for

Select one:

a. Alanine aminotransferase
b. Alcohol Transferase
c. Amino L-transferase
d. Alyl Transferase
e. Aspartate l-transferase

A

Alanine aminotransferase

29
Q

In the normal metabolic pathway the substance from which bilirubin is formed is

Select one:

a. haptoglobin
b. porhyrin
c. urobilinogen
d. biliverdin
e. haemaglobin

A

biliverdin

30
Q

Alkaline phosphatase is NOT concentrated in the

Select one:

a. placenta
b. kidney
c. lung
d. liver
e. bone

A

Lung? (didn’t see the answer but presumably?)

31
Q

The liver enzyme AST is short for

Select one:

a. Aspartate transaminase
b. Aspartate Transferase
c. Alanine synthase
d. Aspartate aminotransferase
e. Alanine S-transferase

A

aspartate aminotransferase

32
Q

Which clotting factor is NOT made in the liver?

Select one:

a. X
b. VIII
c. IX
d. VII
e. II

A

VIII

33
Q

Fibrosis.cirrhosis of the liver is mediated by which type of cell?

Select one:

a. lymphocytes
b. hepatocytes
c. interstitial cells of Ito
d. macrophages
e. neutrophils

A

interstitial cells of Ito

34
Q

Which of the following is NOT associated with acute pancreatitis?

Select one:

a. Caput Medusae
b. renal failure
c. resp failure
d. Grey Turner’s sign
e. Cullen’s sign

A

? (either renal failure or caput medusae)

35
Q

Treatments intended to manage ascites in cirrhosis aim to reduce

Select one:

a. phosphate levels
b. calcium levels
c. magnesium levels
d. sodium levels
e. potassium levels

A

Sodium

36
Q

Microscopically, hepatocytes are bordered by

Select one:

a. Bowman’s space
b. the space of Disse
c. venules
d. Virchow-Robin space
e. arterioles

A

Space of dise

37
Q

Aspiration pneumonia typically occurs in the

Select one:

a. upper post segment of the left lower lobe
b. lower segment of the right lower lobe
c. lower segment of the left lower lobe
d. proximal segment of the right median lobe
e. superior segment of the right lower lobe

A

superior segment of the right lower lobe

38
Q

Embryologically the liver is derived from the

Select one:

a. foregut
b. hindgut
c. the cloaca
d. urachus
e. vitelline duct

A

foregut

39
Q

Alcohol is know to

Select one:

a. decrease blood LDL levels
b. increase blood triglyceride levels
c. increase blood LDL levels
d. increase blood HDL levels
e. decrease blood HDL levels

A

increase blood HDL levels

40
Q

Dupuytren’s contracture is caused by

Select one:

a. scarring of the flexor tendons
b. scarring of flexor policis brevis
c. scarring of the palmar fascia
d. scarring and swelling of the tendon sheath
e. scarring of flexor policis longus

A

scarring of the palmar fascia

alcohol (11 decks)

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