Forensic Aspects of Drug Abuse 3 Flashcards

1
Q

What is PCP?

A
  • dissociative anaesthetic with hallucinogenic properties
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
2
Q

What was PSP first developed as?

A

IV anesthetic for humans

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
3
Q

What are the street names for PCP?

A
  • magic dust
  • angel dust
  • embalming fluid
  • elephant tranquilizer
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
4
Q

What the most common method of ingestion of PCP?

A
  • smoked
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
5
Q

How to they formulate the PCP to enable it to be smoked?

A
  • applied in either powder or liquid form to a variety of leafy substances which can then be smoked in a pipe or homemade
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
6
Q

What are the desired effects of PCP?

A
  • intense euphoria
  • hallucinations
  • relaxation
  • dissociation form the environment
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
7
Q

What is the onset of effect from PCP?

A

1-5 minutes if smoked

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
8
Q

What is the duration of PCP effect?

A

4-6 hours or longer

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
9
Q

What are the physical effects of PCP?

A
  • agitation, confusion
  • disorientation
  • increased pain threshold
  • elevated body temp
  • moon walking
  • cyclic behaviour
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
10
Q

What are the s/s of PCP toxicity?

A
  • delirium
  • hallucinations
  • convulsions
  • violent reactions
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
11
Q

What happens with overdose associated with PCP?

A
  • deep coma
  • seizures
  • death is due to respiratory arrest and potentially cardiac arrest
    (longterm use- can lead to psychosis)
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
12
Q

Does PCP cause both physiological and psychological dependance?

A
  • psych: YES

- physiological: NO

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
13
Q

What kind of drug is GHB classified as?

A

a CNS depressant

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
14
Q

What was GHB used for in the past?

A
  • combo with anaesthetic
  • experimental tx for narcolepsy
  • alcohol withdrawal
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
15
Q

What are the street names for GHB?

A
  • easy lay
  • liquid E
  • G
  • salt water
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
16
Q

What are the desired effects from GHB?

A
  • relaxation
  • sense of well being
  • loss of social inhibitions
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
17
Q

What is the onset of GHB?

A
  • 5-20 minutes
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
18
Q

What is the duration of action of GHB?

A

2-3 hours (makes it difficult because cannot be detected in blood after around 6 hours - implications for date rape trials)

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
19
Q

What are the other effects associated with GHB?

A
  • amnesia
  • drowsiness
  • impaired judgement
  • slowed rxn time
  • slurred speech
  • loss of balance
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
20
Q

At a higher dose, what are the physical reactions to GHB?

A
  • LOC
  • slowed HR
  • seizures
  • decreased resp
  • coma
  • death
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
21
Q

GHB is an ________________

A

endogenous metabolite

22
Q

GHB may be a product of _______ metabolism

A

postmortem

23
Q

What are the properties of cannabis?

A
  • CNS depressant, stimulant and has hallucinogenic properties as well
24
Q

What are the useful properties of cannabis used medicinally?

A
  • antiemetic
  • management of glaucoma
  • antispasmodic
  • appetite enhancer
25
Q

Dronabinol is a synthetic _____________

A

trans (-) isomer of THC

26
Q

What is dronabinol approved for?

A
  • n/v associated with cancer

- anorexia and weight loss with AIDs

27
Q

What is nabilone?

A
  • synthetic chromenone derivative of THC
28
Q

What is nabilone approved for?

A
  • n/v associated with cancer

- anorexia and weight loss with AIDs

29
Q

Sativex is a ______ and _______

A

natural THC and cannabidiol

30
Q

Sativex is approved for what?

A

tx of neuropathic pain and spasticity associated with MS

31
Q

What are the street names associated with cannabis?

A
dope
ganja
grass
J
mary jane
32
Q

What is the best part of the weed plant?

A

resin at the top of the plant has THC that is the best

33
Q

What is the desired effects of cannabis?

A
  • euphoria
  • general sense of well being
  • relaxation
  • loss of inhibition
34
Q

What is the duration of a high from cannabis(smoked)

A

2-3 hours

35
Q

What are the other effects of cannabis? (more physical)

A
  • distortion of time, space, body image
  • impairment of recent memory and concentration
  • mild confusion; disorientation
  • reduced attention span
  • reduced ability to process information
  • difficulty with balance
  • dry mouth
36
Q

What are the s/s of cannabis toxicity?

A
  • fearfulness
  • anxiety
  • mild paranoia
37
Q

What is heroin classified as?

A
  • CNS depressant
38
Q

Heroin is _______ times more potent than morphine

A

2-3 x

39
Q

How is morphine produced?

A
  • by treating morphine with acetic anhydride
40
Q

What are some of the street names associated with heroin?

A
  • antifreeze
  • big H
  • brown sugar
41
Q

What are the methods of heroin ingestion?

A
  • injection
  • smoking
  • snorting
42
Q

What is the point of using a depressant (heroin) at the same time as using a stimulant (crack rocks)

A
  • crack rocks have an effect right away (lasts around 20 minutes) - by the time the crack rocks wear off, then the heroin starts to work
43
Q

What are the desired effects associated with heroin?

A
  • euphoria
  • sense of well being
  • relief of pain
44
Q

What is the onset of heroin action?

A
  • immediate euphoria

- 15-30 minutes for the other physical effects

45
Q

What is the duration of the physical effects associated with heroin?

A

3-6 hours for the physical effects

46
Q

What is the “on the nod”

effect associated with heroin?

A
  • semiconscious
  • droopy eyelids
  • head slumped forward, chin on chest
  • easily awakened
  • altert to questions
47
Q

What narcotic will not cause constricted pupils?

A
  • demerol
48
Q

What are the other physical effects associated with heroin?

A
  • slowed reflexed
  • slow, raspy speech
  • facial itching
  • nausea
  • difficulty with urination
  • slow, deliberate movement
49
Q

What is associated with toxicity of heroin?

A
  • resp depression
  • coma
  • death
50
Q

Does heroin cause both psychological and physiological dependence?

A
  • YES
51
Q

What are the s/s associated with withdrawal?

A
  • insomnia, vomiting, diarrhea, hot and cold flashes, weakness and cold like symptoms
52
Q

What is one of the main interpretation challenges around heroin use?

A
  • heroin is not detected in the body fluids and requires a special extraction procedure(requires extraction at a pH of 8)