Forensic Aspects of Drug Abuse 2 Flashcards
What kind of drug is alcohol classified as?
- CNS depressant
What samples can be used for alcohol analysis?
- blood
- urine
- vitreous humor
- CSF
- bile
- breath
What are the advantages of an alcohol breath analysis?
- noninvasive
- convenient
What is a P considered on a breathalyzer?
0-49 mg%
What is the A considered on a breathalyzer?
50-99 mg%
What is an F on a breathalyzer?
100 mg% or greater
What law is a breathalyzer based upon?
- henry’s law
What is henry’s law?
- the concentration of gas dissolved in a liquid phase is directly proportional to the partial pressure pf the gas in a gaseous phase that is in equilibrium with the liquid
3-5 minutes after drinking alcohol, what is being tested?
- mouth alcohol
____ of alcohol is absorbed in the stomach
30%
____ of alcohol is absorbed in the small intestine
70%
What is the rate of absorption affected by?
- food in the stomach
- speed of consumption
- concentration of alcohol
- drugs (nicotine and caffeine slow rate of abs), disease, emotional state
How do carbonated beverages keep the pyloric valve open?
- carbonation keeps the pyloric valve open- carbonation helps with the absorption of alcohol
What is the typical rate of social consumption of alcohol?
3-4 drinks per hour
What % concentration is the most efficient rate of absorption?
20%
What organs have a higher alcohol concentration?
- liver
- intestine
- brain
What is the widmark hypothesis?
alcohol is distributed in the body in proportion to the water content of the tissues
What does BAC depend on?
- body size (weight)
- body fat (body type)
- gender
Is BAC higher in those with a higher fat content or lower content?
- higher fat content
Absorption = BACxWtx0.022
FOR MEN
abs = mL of liquor
BAC = blood alcohol concentration
wt=KG
Where does most elimination occur for alcohol?
- 90-98% of metabolism occurs in the liver
alcohol-> acetaldehyde -?acetate -> CO2 and H2O
Explain excretion with alcohol?
2-10% of elimination is unchanged (via breath, urine, feces, sweat, tears, saliva)
What is the formula for elimination?
ELIM = metabolism + excretion
What is the average BAC elimination rate for alcohol?
15 mg%/hour