Forensic Aspects of Drug Abuse 2 Flashcards

1
Q

What kind of drug is alcohol classified as?

A
  • CNS depressant
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2
Q

What samples can be used for alcohol analysis?

A
  • blood
  • urine
  • vitreous humor
  • CSF
  • bile
  • breath
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3
Q

What are the advantages of an alcohol breath analysis?

A
  • noninvasive

- convenient

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4
Q

What is a P considered on a breathalyzer?

A

0-49 mg%

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5
Q

What is the A considered on a breathalyzer?

A

50-99 mg%

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6
Q

What is an F on a breathalyzer?

A

100 mg% or greater

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7
Q

What law is a breathalyzer based upon?

A
  • henry’s law
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8
Q

What is henry’s law?

A
  • the concentration of gas dissolved in a liquid phase is directly proportional to the partial pressure pf the gas in a gaseous phase that is in equilibrium with the liquid
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9
Q

3-5 minutes after drinking alcohol, what is being tested?

A
  • mouth alcohol
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10
Q

____ of alcohol is absorbed in the stomach

A

30%

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11
Q

____ of alcohol is absorbed in the small intestine

A

70%

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12
Q

What is the rate of absorption affected by?

A
  • food in the stomach
  • speed of consumption
  • concentration of alcohol
  • drugs (nicotine and caffeine slow rate of abs), disease, emotional state
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13
Q

How do carbonated beverages keep the pyloric valve open?

A
  • carbonation keeps the pyloric valve open- carbonation helps with the absorption of alcohol
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14
Q

What is the typical rate of social consumption of alcohol?

A

3-4 drinks per hour

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15
Q

What % concentration is the most efficient rate of absorption?

A

20%

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16
Q

What organs have a higher alcohol concentration?

A
  • liver
  • intestine
  • brain
17
Q

What is the widmark hypothesis?

A

alcohol is distributed in the body in proportion to the water content of the tissues

18
Q

What does BAC depend on?

A
  • body size (weight)
  • body fat (body type)
  • gender
19
Q

Is BAC higher in those with a higher fat content or lower content?

A
  • higher fat content
20
Q

Absorption = BACxWtx0.022

FOR MEN

A

abs = mL of liquor
BAC = blood alcohol concentration
wt=KG

21
Q

Where does most elimination occur for alcohol?

A
  • 90-98% of metabolism occurs in the liver

alcohol-> acetaldehyde -?acetate -> CO2 and H2O

22
Q

Explain excretion with alcohol?

A

2-10% of elimination is unchanged (via breath, urine, feces, sweat, tears, saliva)

23
Q

What is the formula for elimination?

A

ELIM = metabolism + excretion

24
Q

What is the average BAC elimination rate for alcohol?

A

15 mg%/hour