Forces of Evolutionary change - part 2 Flashcards
Hardy-Weinberg Equilibrium
Population relies on the relationship between allele and genotype frequencies
Allele Frequency =
number of an allele/total number of alleles
Genotype frequency =
number of individuals with a specific genotype/size of population
Hardy-Weinberg Equilibrium situation
highly unlikely situation in which allele frequencies and genotype frequencies do NOT change from one generation to the next
5 assumptions that must be met for Hardy-Weinberg Equilibrium
- Natural selection does not occur
- Mutations do not occur
- Population is large
- Mating is random
- No immigration or emigration
Allele frequency equations
p+q=I
D+d=I (fur color_
use allele frequency to calculate genotype frequency
p to the second power + 2pq + q to the second power = I
Proportion of DD =
p to the second power
5 assumptions that would never happen with Hardy-Weinberg Equilibrium
- Some phenotypes are better adapted to an environment than others
- Mutations introduce new alleles
- Allele frequencies change due to chance (genetic drift)
- Individuals in closed groups (non-random mating)
- Migration among populations
3 types of natural selection
Directional, disruptive and stabilizing selection
Directional natural selection
One extreme is the fittest
Disruptive natural selection
Extremes are selected
Stabilizing Natural Selection
Extremes are less fit than intermediate
example of stabilizing selection
Sickle Cell Anemia
Sickle Cell Anemia
Sickle-shaped RBC