Folliculogenesis

Question 0

What are oogonia?

Answer 0

When primordial germ cells enter the ovary they become oogonia.
They are egg precursors and are diploid.
Must be haploid therefore goes through meiosis

Question 1

What are primordial germ cells (PGCs)?

Answer 1

Germ cells that will become eggs or sperm

Question 2

Once oogonia enters the first stage of meiosis it can still divide to become secondary oocytes
TRUE or FALSE

Answer 2

FALSE

They are stuck in the first stage, no more division occurs and they become primary oocytes

Question 3

What is a follicle?

Answer 3

The cellular structure surrounding and protecting the oocyte.

Question 4

What is the zona pellucida?

Answer 4

The first protective acellular layer of the oocyte.

Question 5

What happens in folliculogenesis?

Answer 5

Oocyte sends message to surrounding cells in stroma which differentiates into granulosa cells
Granulosa cells then secrete a second acellular layer called the basal lamina (no blood vessel)
A second and final layer differentiates around the basal lamina called theca layer (contains blood vessels and make androgens)

Question 6

What is folliculogenesis?

Answer 6

The growth and development of follicles from the earliest resting stages as laid down in foetus through to ovulation.

Question 7

Most follicles in the ovary are not growing, only a few grown at a time
TRUE or FALSE

Answer 7

TRUE

Question 8

What drives most of folliculogenesis?

Answer 8

FSH

Question 9

What happens in the antral phase of folliculogenesis?

Answer 9

Takes follicles into follicular phase of menstrual cycle.
Number of granulosa cells increases, follicle expands and areas of fluid appear in the centre –> called the Antrum
Oocyte is displaced to one side and protrudes into the Antrum on a stalk of granulosa cells.