Foetal Growth Flashcards

Outline nutritional requirements in neonates, children, adolescents and pregnant women and apply this knowledge to clinical scenarios of dietary insufficiency i.e. calorie insufficiency, vit D deficiency, iron deficiency.

1
Q

Trimesters in weeks

A
1 = 0-13 wks
2 = 14-26 wks
3 = 27 - 40 wks
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2
Q

3 main stages off foetal growth

A

wks 0-2 Blastogenesis Stage
Zygote rapidly divides & embeds into endometrial lining; uterus wall.
wks 2-8 Embryonic Stage
Rudiments of principle organs and membranes develop. Nutrients are primarily from maternal blood.
wks 8-40 Foetal Stage
Nutrients supplied via placenta. The tissues and organs continue to grow.

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3
Q

Periconceputal

A

Immediately prior to conception and early gestational Phase

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4
Q

Critical Period of Development

A

Embryonic Stage wk 2 -8

as a lack of certain nutrients may cause specific congenital abnormalities

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5
Q

Majority of Foetal growth takes place

A

90% of Foetal growth takes place during the second half of pregnancy

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6
Q

Estimated Energy Requirements for Pregnancy

A

estimated energy cost of 40wk pregnancy is 322MJ/7700kcal

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7
Q

Energy Requirements for Pregnancy

A

1st trimester has a low rate energy demand, whilst third trimester needs additional increment to cope with increased energy demand.

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8
Q

Neural Tube Defects

A

Anencephaly - incomplete closure of upper end of the neural rube
Spina Bifida - incomplete closure of Spinal cord (Split spine)

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9
Q

Nutrients in Pregnancy

Vit A

A

In pregnancy recommended:
Avoiding excess and deficiency;
ensuring avoiding retinol food like liver, oils and supplements. Instead incorporating milk, eggs, carrots and leafy greens B-carotene’s the body naturally changes to retinol in excess

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10
Q

Nutrients in Pregnancy

Vit D

A

In pregnancy recommended:
Low vit D leads to congenital rickets and impaired foetal/infant skeletal growth in absence of rickets.
RNI is 10µg a day

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11
Q

Nutrients in Pregnancy

Calcium

A

In pregnancy recommended:
Required for calcification of foetal skeleton
RNI 700mg a day

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12
Q

Maternal adaptions for Ca requirements

A

The female body adapts to meet calcium requirements by
– ↑ intestinal absorption of dietary Ca
– ↑ reabsorption of Ca by kidneys = enhanced retention
– ↑ bone turnover to release Ca

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13
Q

Nutrients in Pregnancy

Iron

A

The maternal requirement increases as pregnancy progresses.
There can be infant Fe deficiency anaemia due to maternal Fe deficiency anaemia
Fe insufficency can increase chance of preterm delivery

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14
Q

Maternal adaptions for Fe requirements

A
Female body adapts via
Amenorrhoea,
 ↑ absorption of dietary of non-haem Fe 
Mobilisation of maternal stores
Foetus also acts like a parasite drawing on maternal stores
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15
Q

Exclusive breastfeeding

A

No food or drink inc water except for breast milk

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16
Q

Weaning

A

“The process of expanding diet to
include food and drinks other than breast milk or
infant formula”

17
Q

WHO Guidelines on Postnatal nutrition

A

Exclusive breastfeeding is recommended for the first
6 months (26 weeks) of an infant’s life as it provides
all the nutrients a baby needs
Introduce a variety of complementary foods at
around 6 months alongside continued breastfeeding
(and/or breast milk substitutes, if used)

18
Q

BreastMilk composition

A

Tends to have optimal nutrition condition if mother not deficient.
Contains bioactive factors which help confer immunological protection such as macrophages, neutrophils and lymphocytes. Immunoglobulins such as IgA, IgG, lysozymes, lactoferrin, bifidus factor, complement and interferon.
However iron concentration is low though more bioavailable.

19
Q

Weaning

A

Weaning should begin no eariler than 4 months but no later than 6 months due to low concentrations of Iron in blood.