FNP Boards Flashcards
What is Chronic bronchitis
a type of COPD that is characterized by inflammation of the bronchi, causing excess mucus
Characteristics of chronic bronchitis (4)
diagnosis after age 35, obesity, copious amounts of purulent sputum, elevated Hct level
Tx chronic bronchitis
Treat with SABA (albuterol), inhaled anticholinergics (ipratropium)
Lung Assessment findings of chronic bronchitis
- Lower lobes vesicular breath sounds (soft and low)
- Upper lobes; Bronchial breath sounds louder
Actinic keratosis: who gets it/ who’s at risk
Older to elderly fair-skinned adults frequent sunburns as child places person at higher risk
Actinic keratosis: what does it look like
numerous dry, round, pink to red-colored, slow-growing lesions that do not heal
Actinic keratosis: where is it
lesions common on sun-exposed areas (cheeks, nose, face, arms, back)
Actinic keratosis: what is it
precancerous precursor of squamous cell carcinoma
Actinic keratosis: diagnosis and tx
- diagnosed with biopsy
- treat with cryotherapy (small number) or 5-FU(5% fluorouracil) cream (large number)
- follow up with derm
Seborrheic keratosis: what is it and what does it look like
- soft, round, wart-like fleshy growths on trunk (mostly on back)
- can range in color from light tan to black
- appear to be pasted on
- asymptomatic
- benign
Fingernail hematoma treatment
Trephination: make hole in nail through drilling or piercing and allow blood to drain
Primary Hypothyroid labs
elevated TSH; low T4; low or normal T3
Subclinical Hypothyroid labs
elevated TSH; normal T4; normal T3
Hypothyroid common cause
Hashimoto’s (autoimmune)
-Remember Hashimoto and Hypo both have O
Hypothyroid tx and follow up
- levothyroxine (Synthroid) daily in AM on empty stomach
- Starting dose of levothyroxine (Synthroid) is 25-50mcg
- Check TSH every 6-8 weeks to monitor treatment response
Primary hyperthyroid labs
low TSH; high T4; normal or high T3
Subclinical Hyperthyroid labs
low TSH; normal T4; normal T3
Hyperthyroid most common cause
Grave’s Disease (autoimmune)
-Remember Grave and Hyper both have R
Hyperthyroid symptoms
rapid weight loss; increased heart rate; tremors; sweating; irritability; anxiety; hyperactivity; insomnia; diarrhea; amenorrhea; hypertension; exophthalmos; heat intolerance; goiter
Hyperthyroid tx
- Propylthiouracil (PTU)
- Methimazole (Tapazole)
- Radioactive iodine (causes hypothyroid for life, contraindicated in pregnancy)
Thyroid Storm (thyrotoxicosis)
acute worsening of symptoms; may be caused by stress or infection; look for LOC, fever, abdominal pain; life-threatening; immediate hospitalization needed
Ectopic pregnancy risk factors
previous ectopic, salpingitis, tubal surgery, current IUD use, previous cervicitis, history of PID
Ectopic pregnancy symptoms
abdominal pain (worsens when supine or with jarring), vaginal bleeding, amenorrhea, low grade fever, pain referred to right shoulder (may indicate rupture)
HTN meds for African-American with or without diabetes
initial choices include thiazide diuretic or CCB
HTN meds for Non-Black with or without diabetes
initial choices include thiazide diuretic, CCB, ACE, or ARB
Thiazide diuretics
“ide”
- excellent synergist
- avoid in sulfa allergy
- favorable in osteopenia/osteoporosis
- lowers BP only 2-8 points
Thiazide diuretics side effects
-hyperglycemia (caution in diabetics), -hyperuricemia (gout attack), -hypertriglyceridemia and hypercholesteremia (check lipid profile), -hypokalemia (potentiates digoxin toxicity and increases risk for arrhythmia), -hyponatremia (hold diuretic, restrict fluid, replace K+)
Ace inhibitors and ARBs
- ACE: “pril”
- ARB – “sartan”
- use in high renin states
- drug of choice in diabetics (protects kidneys)
- pregnancy category C/D
Ace inhibitors and ARBs side effects
dry/hacking cough (more with ACE), hyperkalemia, angioedema (rare, life-threatening); contraindicated in moderate to severe kidney disease; do not use ACE and ARB together
Beta blocker
“lol”
- good as add-on medication, not uncomplicated HTN
- avoid abrupt discontinuation, wean slowly to avoid rebound HTN
Beta blocker contraindication
asthma, COPD, chronic bronchitis, emphysema, second and third-degree heart block (okay with 1st degree), sinus bradycardia; do not use Propranolol for HTN
Calcium channel blocker
“pine”
-first choice for ISH (isolated systolic HTN);
Calcium channel blocker side effects
-headaches (vasodilation), ankle edema (vasodilation, benign), heart block/bradycardia (depresses cardiac muscle and AV node), reflex tachycardia (nifedipine)
Calcium channel blocker Contraindications
2nd and 3rd degree heart block, bradycardia, CHF
HTN tx for heart failure
ACEI or ARB as first line, plus BB, plus diuretic
HTN tx for diabetes
ACE/ARB first line,
*IF AA can start with CCB or Thiazide
HTN tx for CKD
ACE/ARB first line, can add CCB or Thiazide
HTN tx for stroke hx
ACE/ARB first line, add CCb or Thiazide as second line drugs
HTN tx for Bilateral Renal artery stenosis
ACE AND ARB will WORSEN or cause acute renal failure. CONTRAINdicated!!
Risk factors for post-menopausal osteoporosis
older women; white/Asian descent; thin; small body frame; chronic steroids; androgen deficiency; hypogonadism; anorexia; bulimia; gastric bypass; celiac disease; hyperthyroidism; ankylosing spondylitis; RA; low calcium intake; vitamin D deficiency; inadequate physical activity; alcohol/caffeine intake; smoking
Legg-Calves-Perthes: what is it
Osteonecrosis of the capital femoral epiphysis due to interrupted vascular supply
Legg-Calves-Perthes: who does it affect
- Common in ages 3-12 (pre-pubescent)
- More common in males
Legg-Calves-Perthes symptoms
- Pain in hip or referred to medial aspect of knee (may be present for 2-3 weeks before complaints)
- Limp
Legg-Calves-Perthes testing
Positive Trendelenburg’s Test (asking child to stand on affected side causes pelvic tilt – affected side lower)
Cranial Nerves III, IV, VI to assess EOM
- III – oculomotor – eye movements, pupillary constriction, accommodation
- IV – trochlear – movement of superior oblique muscle
- VI – abducens – movement of lateral rectus muscle
- Mnemonic – LR6SO4 (lateral rectus – VI, superior oblique – IV)
How do you check executive function in dementia
ability to manage a calendar
How to treat chlamydia in pregnant woman
- Azithromycin 1g PO single dose or Amoxicillin 500mg PO TID x 7 days
- Test of cure 3 weeks after completion of treatment
Untreated gonorrhea consequences
- Women – PID, abscess, ectopic pregnancy, infertility, can pass to baby during delivery
- Men – epididymitis, infertility
- Both – can spread to blood and cause disseminated gonococcal infection (DGI) which is characterized by arthritis, tenosynovitis, and/or dermatitis and may be life-threatening; increases risk for HIV
Dacrocystitis: what is it
infection of lacrimal sac/tear duct usually caused by blockage
Dacrocystitis: who does it affect
common in infants, adults over 40 also have higher risk of developing
Dacrocystitis: symptoms
thick eye discharge, pain, redness/swelling/warmth of lower eyelid, watery eye/excess tears
Dacrocystitis: tx
lacrimal sac massage (downward toward mouth) 2-3 times daily; systemic antibiotics 7-10 days
Erysipelas: what is it/what causes is
- subtype of cellulitis involving upper dermis and superficial lymphatics
- usually caused by Group A Strep
Erysipelas symptoms
single large lesion, hot, indurated, red, clear demarcated margins, usually found on lower legs (shins) or cheeks, fever, chills
Retinoblastoma: what is it/ how is it diagnosed
- rare type of cancer
- diagnosed by noting white pupil or pupil with white spots on it (leukocoria) – hallmark sign
- may affect one or both eyes
Carotid bruit cause
caused by carotid stenosis (cholesterol plaque accumulation)
What murmur that radiates to the neck
Aortic stenosis
Systolic murmurs
-MR. ASS: Mitral Regurg, Aortic Stenosis
OR
-MR Peyton Manning AS MVP: Mitral Regurg, Physiologic Murmur, Aortic Stenosis, Mitral Valve Prolapse
Diastolic murmurs
MS ARD: Mitral Stenosis, Aortic Regurg
Where to hear murmurs
- rIght-sided – louder on Inspiration
- lEft-sided – louder on Expiration
- aoRtic – Right side
- puLmonic – Left side
Mitral Regurg: where is it heard, symptoms, test results
- pansystolic/holosystolic; heard best at apex; radiates to left axilla; loud blowing/high-pitched; usually result of congenital condition, rheumatic heart disease, acute endocarditis, MVP, calcified annulus;
- symptoms include CHF, fatigue, dyspnea, bacterial endocarditis; LV/LA enlarged on XR; Afib common on EKG
Aortic Stenosis: where is it heard, complications, test results
- midsystolic; best heart at 2nd ICS on right side; radiates to neck; harsh/noisy; patients should avoid physical overexertion (increased risk of sudden death);
- complications include angina, syncope, CHF; cardiomegaly occurs late; EKG usually normal; usually audible S4; usually congenital; rheumatic fever 2nd most common cause; monitor with echo; surgical valve replacement if worsens
Mitral Valve Prolapse: where is it heard, symptoms, complications, test results
- systolic; heard best at apex; more common in women ages 14-20
- symptoms include palpitations, chest pain, dyspnea, dizziness, numbness; first finding is midsystolic “click”;
- EKG usually normal. Rule out marfans syndrome in tall thin female with hypermobile joints. Arm span greater than height etc.
Mitral Stenosis: where is it heard, etiology, stages, syptoms
- low-pitched diastolic; rumbling; heard best at apex; “opening snap”;
- etiology is rheumatic fever;
- 4 stages (1 – long asymptomatic period followed by gradual reduction in exercise tolerance, 2 – pulmonary congestion, 3 – pulmonary HTN, 4 – severe low CO); -symptoms include dyspnea, Afib, hemoptysis, RV hypertrophy; loud S1; may radiate toward axilla
Aortic Regurg: where is it heard, symptoms, etiology
- diastolic; high-pitched; blowing; best heard at 2d ICS on right side of sternum; -symptoms include angina, CHF, dizziness, chest pain;
- etiology includes rheumatic heart disease, congenital deformity, aortic root abnormalities, syphilis; PMI displaced downward and left; water-hammer pulse
Patient forgot to start Thanksgiving dinner and husband states she has trouble remembering tasks and trouble with organization. This is indicative of:
- Loss of executive function
- Executive function includes the ability to manage a calendar, organizing, planning (getting things started), multitasking, processing/storing information
Patients with Atopic dermatitis would be at risk for what other conditions?
-asthma, allergic rhinitis, multiple allergies
Atopic dermatitis tx
topical steroids (1st line); systemic oral antihistamines; skin lubricants; hydrating baths
Atopic dermatitis: what is it
atopic dermatitis (eczema) is marked by extremely pruritic rashes on hands, flexural folds (antecubital/popliteal space), and neck; rash is exacerbated by stress and environmental factors; rash appears as multiple small vesicles that rupture and leave painful, bright red, weepy lesions that become lichenified from chronic itching; fissures can form and can be infected with bacteria
Patient with history of PID has increased risk for:
infertility
Main symptom of PID
• cervical motion tenderness indicates PID
PID tx and follow up
- treat symptomatic PID even if GC and chlamydia tests are negative
- follow up with vaginal bimanual exam in 2-3 days to make sure symptoms are improving
Treatment for gonorrhea
- Ceftriaxone (Rocephin) 250mg IM x 1 dose plus
- Azithromycin (Zithromax) 1gm oral or Doxycycline (Vibramycin) 100mg BID x 7 days
Old lady with weakness on 2 HTN meds, 2 DM meds, vitamins: what’s wrong with this?
- polypharmacy
- hypotension
- hypoglycemia
Wilm’s tumor: what is it
- nephroblastoma
- asymptomatic abdominal mass that extends from flank toward midline
- nontender, smooth mass that rarely crosses midline of abdomen
Wilm’s tumor: who does it affect
- higher incidence in black, female children
- peak age 2-3
- most common renal malignancy in children
Wilm’s tumor: careful when performing physical exam
palpate gently to avoid rupturing renal capsule
Wilm’s tumor: testing
initial test is abdominal ultrasound
Follow up for baby with UTI
-renal and bladder ultrasound (RBUS) for all infants 2-24 months for first febrile UTI
Definitive diagnosis of acute bacterial prostatitis
- UA and culture (treat empirically until results are back)
- Avoid vigorous palpation and massage of prostate – can lead to septicemia
Treatment of acute bacterial prostatitis
- Under age 35, treat like gonorrhea or chlamydia – Rocephin 250mg IM plus doxycycline 100mg PO BID x 10 days
- Over age 35, unlikely STD in nature, treat with Cipro PO BID or Levaquin PO daily x 4-6 weeks
AV nicking
- HTN stiffens vessels
- arteries indent and displace veins
- considered “mild” retinopathy
What causes Cotton wool spots on fundoscopic exam
- can be caused by HTN, DM, or other causes – microinfarct occurs
- considered “moderate” retinopathy
High triglycerides and pancreatitis association and tx
- high risk of acute pancreatitis with triglycerides greater than 500
- normal level is less than 150
- if triglycerides are greater than 500, treat with niacin or fibrate or Niaspan to lower triglycerides; if less than 500, consider lifestyle modifications first
- once triglycerides are under control, switch target to lowering LDL
- recommend low fat diet, weight loss, and increased physical activity
Pancreatitis diagnosing with labs
- diagnosed with amylase and lipase lab draw
- amylase begins increasing 2-12 hours after onset of symptoms
- amylase is most widely used method of diagnosing pancreatitis
- lipase begins to increase 4-8 hours after onset of symptoms
- lipase more specific and sensitive to alcoholic pancreatitis
Osgood Schlatter Disease: what is it
- common cause of knee pain in young athletes, especially if recent growth spurt
- anterior knee pain that increases over time
- osteochondritis of tibial tubercle
- caused by overuse of knee – repetitive stress on patellar tendon by quadriceps causes pain, tenderness, swelling
- usually affects one knee, but can be bilateral
Osgood Schlatter Disease: tx
- treatment – rest/activity as tolerated; ice; analgesics PRN
- rule out avulsion fracture if acute onset of pain post-trauma (lateral x-ray)
When to start patient on high intensity statin
- LDL >190; history of CHD or stroke
- High intensity statins include Atorvastatin (Lipitor) and Rosuvastatin (Crestor)
- Start screeing at 20 then every 5 years until 40 if no issues. At 40 every 2-3 years. IF dx then annually etc
What is a statin
HMG CoA reductase inhibitors
Statin interactions and no nos
- Do not mix with grapefruit juice
- Drug-induced hepatitis or rhabdomyolysis higher if mixed with azole antifungals
- Also interact with fibrates (except fenofibrate), macrolides, amiodarone, and some CCBs
- High-dose Zocor has highest risk of rhabdomyolysis
How much does statin affect LDL
- High intensity statins (atorvastatin/Lipitor, Rosuvastatin/crestor) lower LDL by 35-63%
- Moderate intensity statins (Simvastatin, Pitavastatin, Pravastatin) lower LDL by 22-47%
Starting statin for Secondary Prevention ASCVD
- Patient with any form of ASCVD history of MI, CAD, Angina, stroke/TIA, PAD, coronary revascularization.
- If younger then 75 start on HIGH INTENSITY STATIN.
- if Older than 75 (or not a candidate for high intensity) MODERATE INTENSITY statin.
Starting statin for primary prevention
- NO ASCVD hx, LDL at 190 or greater: give HIGH
- DM aged 40-75 with LDL 70-189 MODERATE
- Without DM or ASCVD age 40-75 with an estimated 10 yr ascvd risk of 7.5% or higher MOD to HIGH
- Lack of any ASCVD but 10year is 5- <7.5% FIRST LINE is heart healthy lifestyle changes
Pap Smear recommendations
- Begin Pap at age 21 and repeat every 3 years until age 29
- Age 30 – Pap and HPV (primary screening); repeat every 5 years if negative
- Beginning age 65, may stop Pap if negative history x 10 years
- Discontinue in patients who have had hysterectomy with removal of cervix and no history of cervical cancer or high-grade lesion
- Satisfactory specimen only if both squamous epithelial cells and endocervical cells are present; if endocervical cells are missing, repeat Pap
MRSA treatment in patient with allergies
- If patient has sulfa allergy, treat MRSA with a tetracycline (doxycycline, minocycline)
- If no sulfa allergy, use Bactrim
Patient has acute otitis media; gets hives with amoxicillin and n/v with erythromycin; treatment
- Trimethoprim sulfamethazole (Bactrim DS) PO BID
- Levofloxacin (Levaquin) or moxifloxacin (Avelox) – only if patient is 18 years or older – increases risk for tendonitis/Achilles tendon rupture
- If only Penicillin allergy, use azithromycin x 5 days or clarithromycin PO BID
McMurray Sign
- Knee pain and a “click” sound upon manipulation of the knee equals positive sign
- Suggests injury to medical meniscus
- Gold standard test for joint damage is MRI
Medial Pain in knee (Valgus/Varus)
- Valgus stress test – medial collateral ligament (MCL)
- Varus stress test – lateral collateral ligament (LCL) – Varus and Lateral both have R
- Positive finding is an increase in laxity of the damaged knee (ligament tear)
Sickle Cell Teaching
- Diagnosis confirmed with hemoglobin electrophoresis (gold standard)
- suggest genetic counseling
- increased risk for death from infection with encapsulated bacteria due to hyposplenia
- recommend all required vaccinations
Bumps start on face or trunk and spread to rest of body: what disease is it
- Varicella
- Classic presentation – pruritic vesicular lesions in different stages of development and healing
Adolescent with mild persistent asthma – treatment?
- low dose ICS plus SABA (albuterol) PRN (preferred treatment)
- Montelukast, nedocromil, or theophylline
- Remember all asthma patients must have SABA as rescue med (safety issue)
Infant had 2 episodes of RSV/bronchiolitis; now presents with fever, cough, wheezing; differentials do not include:
-foreign body
Female with yellow/green vaginal discharge and itching?
- trichomoniasis
- symptoms – frothy, yellow/green discharge; strawberry cervix; dysuria; vulvar irritation; pruritis; pH>5.0
- treatment – metronidazole (Flagyl) 2g x 1 dose or 500mg BID x 7 days; treat partner
Most common bug for otitis media
- streptococcus pneumoniae
- treatment – amoxicillin is gold standard for all ages; if recent amoxicillin use or failed amoxicillin therapy, consider augmentin
Most common cause of death in women
- heart disease
- heart disease is also the most common cause of death in men
- cancer is second most common
Lab test for Fifth Disease (erythema infectiosum)
- Parvovirus B19
- Diagnosis is usually made based on clinical presentation – “slapped cheek” – instead of lab test
- more common in children
- contagious through respiratory secretions
Fifth Disease (erythema infectiosum) symptoms
fever, headache, runny nose, rash
Person eating and notices a painful lump in jaw that comes and goes
- sialolithiasis
- can also cause painful lump under the tongue, pain/swelling near ear or under jaw, dry mouth, gritty/strange tasting saliva, difficulty opening mouth, difficulty swallowing
- caused by salivary duct obstruction – worse when eating due to increased saliva production
ADHD symptoms
hyperactivity, impulsivity, inattention (behavior disorder)
ADHD diagnostic criteria
- symptoms present prior to age 12; -symptoms last > 6 months;
- symptoms should be evident in 2 different settings (school and home – get feedback from caregiver/parent and teacher/coach)
ADHD tx
Schedule II medications – high potential for abuse
Patient complains about upper arm tremor that seems to be hereditary; treatment?
- likely essential tremor
- treated with beta-blocker (Propranolol 60-320mg per day)
- alternative treatment is primidone (50-1000mg per day)
Highest suicide rates
- Age: 45-54 and >80
- Race: white
- Sex: male (females attempt more often, but males have a higher success rate)
Suicide risk factors
loss of spouse; history of attempted suicide; family history of suicide; mental illness; bipolar; depression; history of abuse; terminal or chronic illness; chronic pain; substance/alcohol abuse; significant loss (job, friend, divorce, death of someone close); plan to use gun
Fructosamine Test
- similar to hemoglobin A1c
- indicate the average level of blood glucose control over the past 2-3 weeks
- increased level associated with prolonged hyperglycemia for 2-3 weeks prior to testing
- higher the level, poorer the degree of the glycemic control
- trend from high to normal may indicate treatment regimen is effective
- not used for screening
Treatment to prevent fracture in patient with low vitamin D, high TSH, low Hct
- Vitamin D 600-800 IU/day
- Calcium 1000-1200mg/day
Temporal Arteritis: diagnosis
• gold standard for diagnosis – temporal artery biopsy done by ophthalmologist
Temporal Arteritis: screening
erythrocyte sedimentation rate (ESR)
Temporal Arteritis:symptoms
acute onset of unilateral headache located on the temple; jaw claudication (with chewing); fever; visual loss; pain in temple area