FM 3 Flashcards
increased TLC, RV, FRC
obstructive— COPD, asthma
***hyperinflation
Decreased TLC, RV, FVC
restrictive
Asthma
-diagnosis, how to confirm, best way to assess exacerbation
H&P, PE findings
CONFIRM diagnosis is w/ PFT– need to stop bronchodilators before test—will show obstructive pattern– decreased FEV1/FVC
best way to assess exacerbation is peak expiratory flow rate
samters triad
ASA allg
nasal polyps
asthma
atopic triad
eczema
allergic rhinitis
asthma
symptoms <2 times per week, nightitme symptoms 1-2x/month. use of SABA <2days / week
intermittent asthma
symps >2x/week, nightime symptoms 3-4x/month, use of SABA >2 days/week
mild persistent asthma
daily symptoms, nightime symptoms > or eqaul to 5 times per month, daily use of SABA
mod persistnet asthma
continous symptoms with daily night-time awakenings, SABA several times per day
severe persistent asthma
asthma diagnosis: Greater than ____% increase in FEV1 after bronchodilator therapy
12
tx for:
-mild intermittent
SABA PRN
tx mild persistnet asthma
low dose ICS daily and SABA PRN
moderate persistent asthma tx
low-dose ICS + LABA daily
OR if that doesnt work
medium dose ICS + LABA daily
severe persistent asthma tx
high dose ICS + LABA daily
then if that doesnt work
High dose ICS + LABA + PO steroids daily
list the step wise appraoch for asthma tx
- SABA prn
- low dose ICS daily
- low dose ICS + LABA
- medium dose ICS + LABA
- high dose ICS + LABA
- high dose ICS + LABA + PO steroids daily
list short acting beta agonists
albuterol
levalbuterol
define bronchitis
-etiologies
cough >5 days with (MC) or w/o sputum production lasting 2-3 weeks
+/- HA, low grade fever, sore throat
etiologies
MC=viral— adenovirus MC, rhinovirus, RSV, influenza, corona,
bacterial causes= mycoplasma, bordetella pertusis
**if there is HIGH FEVER AND LOTS OF SPUTUM, TACHYCARDIC, TACHYPNIC— consider pnemonia and get CXR
tx=supportive–
COPD
- define
- diagnosis–gold standard
- labs and why
- tx—- WHATS THE ONLY TX TO REDCE MORTALITY
chronic cough that is productive occuring on most days of 3 months of the year for at least 2 or more consecutive yrs w/o defined acute cause
DX
- GS—- PFTs—–> show V/Q mismatch and FEV1/FVC ration less than 0.7
- CXR— only used to r/o pneumonia or pneumothorax… can also be useful in exacerbation
LABS
-incr hgb and hematocrit bc of the chronic hypoxic state
TX
1st step: quit smoking and give pneumococcal vaccine
2. bronchodilators—- anticholinergics, beta ags, corticosteroids
3. OXYGEN IS THE ONLY THERAPY TO REDUCE MORTALITY and quiting smoking
4. alpha 1 anti tyrpsin def— lung transplant only tx
5. azithromycin can be helpful in exacerbations/inflammation
lung cancer screening gudielines
low dose CT in those aged 50-80 with a 20+ pack year hx and currently smoking OR have quit in the last 15 yrs
minimal cough, thin, barrel chest, quiet lungs
emphysema
criteria for home oxygen for COPD pt
- Pa02 55 mm hg
- 02 sat <88% at rest or exercise
- pa02 55-59 + polycythemia or cor pulmonale
- nocturnal hypoxemia—– CPAP
mc type of lung CA
non small cell— 85%
how does small cell lung CA present
recurrent pnma
-anorexia, wt loss, wekeanss, cough
list pe finding for horner syndrome
unilateral facial anhidrosis, ptosis, miosis
where is small cell located
central
*** smokers
non small cell lung CA
-types
squamous cell— central mass
-can lead to hypercalcemia thru paraneoplastic syndrome
adenocarcinoma— MC—peripheral mass— assoc with smoking + asbestos
which lung CA cannot be tx with surgery
small cell
tx for croup
antipyretics, hydration, humidified air (or oxygen), nebulized racemic epinephrine (only if signs of distress), and corticosteroids (dexamethasone
diagnosis for sleep apnea
polysomnography= GS
>15 events/hr + apena are + findings
tx for OSA
- LFM– lose weight**,exervise, decr ETOH, etc
- cpap
- very severe or refractory— uvulopalatopharyngoplasty— UPPP
MCC for CAP
- young adults
- COPD
- overall
- infants
- mc viral in adults
others
strep pneumoniae overall
young adults= mycoplasma
OTHERS -haemophlus--- 2nd mc and assoc with COPD -influenzae -mycoplasma pneumoniae -staph aureus -n. meningitiis - m. catarrhalis -
INFANTS– RSV.. virla
viral adults— influenza
GI s/s + high fever + produtive cough + malaise
legionella pneumoina
pnma prevention
Pneumovax 23– all adults 65+, adults 18-64 who are smokers or have o ther condiitons that make them high risk
PCV or prevnar 13— vaccine for all kids <2 YO and high risk aduls >65
tx for CAP outpatient
- w/o and w/ comorbids
- smoker
with no comorbidities
amox PO or Doxy or Macrolide (clarithromcin or azithromycin) PO*** 5 days or until afebrile
with comorbidities or >65
- beta lactam (amox HD or augmentin) + macrolide PO
- respiratory fluoro– moxifloxacin or levofloxacin
Smokers
-cefdinir
smoking causes what in bladder
transitional cell carcinoma
smoking cessation
-tx— first line.. which is most efficacious
second line
- Varenicline (chantix)– best efficacy bc reduces reward aspect of smoking–quit smoking 1 wk after start
- Bupropion— wellbutrin, Zyban—- YES USE IN PREGNANCY
- Nicotine replacement therapy (NRT)— rec for inpatient
SECOND LINE
1. Nortriptyline and Clonidine
- **every pt gets CBT
- ***f/u appointment 1-2 wks after treatment start