FM 3 Flashcards
increased TLC, RV, FRC
obstructive— COPD, asthma
***hyperinflation
Decreased TLC, RV, FVC
restrictive
Asthma
-diagnosis, how to confirm, best way to assess exacerbation
H&P, PE findings
CONFIRM diagnosis is w/ PFT– need to stop bronchodilators before test—will show obstructive pattern– decreased FEV1/FVC
best way to assess exacerbation is peak expiratory flow rate
samters triad
ASA allg
nasal polyps
asthma
atopic triad
eczema
allergic rhinitis
asthma
symptoms <2 times per week, nightitme symptoms 1-2x/month. use of SABA <2days / week
intermittent asthma
symps >2x/week, nightime symptoms 3-4x/month, use of SABA >2 days/week
mild persistent asthma
daily symptoms, nightime symptoms > or eqaul to 5 times per month, daily use of SABA
mod persistnet asthma
continous symptoms with daily night-time awakenings, SABA several times per day
severe persistent asthma
asthma diagnosis: Greater than ____% increase in FEV1 after bronchodilator therapy
12
tx for:
-mild intermittent
SABA PRN
tx mild persistnet asthma
low dose ICS daily and SABA PRN
moderate persistent asthma tx
low-dose ICS + LABA daily
OR if that doesnt work
medium dose ICS + LABA daily
severe persistent asthma tx
high dose ICS + LABA daily
then if that doesnt work
High dose ICS + LABA + PO steroids daily
list the step wise appraoch for asthma tx
- SABA prn
- low dose ICS daily
- low dose ICS + LABA
- medium dose ICS + LABA
- high dose ICS + LABA
- high dose ICS + LABA + PO steroids daily
list short acting beta agonists
albuterol
levalbuterol
define bronchitis
-etiologies
cough >5 days with (MC) or w/o sputum production lasting 2-3 weeks
+/- HA, low grade fever, sore throat
etiologies
MC=viral— adenovirus MC, rhinovirus, RSV, influenza, corona,
bacterial causes= mycoplasma, bordetella pertusis
**if there is HIGH FEVER AND LOTS OF SPUTUM, TACHYCARDIC, TACHYPNIC— consider pnemonia and get CXR
tx=supportive–
COPD
- define
- diagnosis–gold standard
- labs and why
- tx—- WHATS THE ONLY TX TO REDCE MORTALITY
chronic cough that is productive occuring on most days of 3 months of the year for at least 2 or more consecutive yrs w/o defined acute cause
DX
- GS—- PFTs—–> show V/Q mismatch and FEV1/FVC ration less than 0.7
- CXR— only used to r/o pneumonia or pneumothorax… can also be useful in exacerbation
LABS
-incr hgb and hematocrit bc of the chronic hypoxic state
TX
1st step: quit smoking and give pneumococcal vaccine
2. bronchodilators—- anticholinergics, beta ags, corticosteroids
3. OXYGEN IS THE ONLY THERAPY TO REDUCE MORTALITY and quiting smoking
4. alpha 1 anti tyrpsin def— lung transplant only tx
5. azithromycin can be helpful in exacerbations/inflammation
lung cancer screening gudielines
low dose CT in those aged 50-80 with a 20+ pack year hx and currently smoking OR have quit in the last 15 yrs
minimal cough, thin, barrel chest, quiet lungs
emphysema
criteria for home oxygen for COPD pt
- Pa02 55 mm hg
- 02 sat <88% at rest or exercise
- pa02 55-59 + polycythemia or cor pulmonale
- nocturnal hypoxemia—– CPAP
mc type of lung CA
non small cell— 85%
how does small cell lung CA present
recurrent pnma
-anorexia, wt loss, wekeanss, cough
list pe finding for horner syndrome
unilateral facial anhidrosis, ptosis, miosis
where is small cell located
central
*** smokers
non small cell lung CA
-types
squamous cell— central mass
-can lead to hypercalcemia thru paraneoplastic syndrome
adenocarcinoma— MC—peripheral mass— assoc with smoking + asbestos
which lung CA cannot be tx with surgery
small cell
tx for croup
antipyretics, hydration, humidified air (or oxygen), nebulized racemic epinephrine (only if signs of distress), and corticosteroids (dexamethasone
diagnosis for sleep apnea
polysomnography= GS
>15 events/hr + apena are + findings
tx for OSA
- LFM– lose weight**,exervise, decr ETOH, etc
- cpap
- very severe or refractory— uvulopalatopharyngoplasty— UPPP
MCC for CAP
- young adults
- COPD
- overall
- infants
- mc viral in adults
others
strep pneumoniae overall
young adults= mycoplasma
OTHERS -haemophlus--- 2nd mc and assoc with COPD -influenzae -mycoplasma pneumoniae -staph aureus -n. meningitiis - m. catarrhalis -
INFANTS– RSV.. virla
viral adults— influenza
GI s/s + high fever + produtive cough + malaise
legionella pneumoina
pnma prevention
Pneumovax 23– all adults 65+, adults 18-64 who are smokers or have o ther condiitons that make them high risk
PCV or prevnar 13— vaccine for all kids <2 YO and high risk aduls >65
tx for CAP outpatient
- w/o and w/ comorbids
- smoker
with no comorbidities
amox PO or Doxy or Macrolide (clarithromcin or azithromycin) PO*** 5 days or until afebrile
with comorbidities or >65
- beta lactam (amox HD or augmentin) + macrolide PO
- respiratory fluoro– moxifloxacin or levofloxacin
Smokers
-cefdinir
smoking causes what in bladder
transitional cell carcinoma
smoking cessation
-tx— first line.. which is most efficacious
second line
- Varenicline (chantix)– best efficacy bc reduces reward aspect of smoking–quit smoking 1 wk after start
- Bupropion— wellbutrin, Zyban—- YES USE IN PREGNANCY
- Nicotine replacement therapy (NRT)— rec for inpatient
SECOND LINE
1. Nortriptyline and Clonidine
- **every pt gets CBT
- ***f/u appointment 1-2 wks after treatment start
Mantoux test results POS test:
>5 mm
>10 mm
>15 mm
> 5
*high risk, immunocomp, steroids/TNF agents, close contact with pt infected
> 10
- HOSPITALS AND OTHER HEALTHCARE WORKERS
- IVDU
- recent immigrant
- homeless
- DM
- head/neck CA
> 15
*no risk factors
PPD + and CXR negative– type of TB and tx
Latent TB
Isoniazid for 9 MO + B6 to prevent neuropathy
PPD+ and CXR+
type of TB and tx
Active TB
QUAD TX–RIPE x8 weeks and then RI for 16 weeks
Rifampin Isoniazid Pyrazinamide Ethambutol ****all are hepatoxic
SE of the RIPE drugs
Rifampin— red-organe urine, hepatitis
Isoniazid— peripheral neuropathy– B6 or pyridoxine given to prevent
Pyraziamide—hyperurecemia–gout
Ethambutol– optic neuritis, red-green blindness
prophylaxis for household members around a TB+ patient
isoniazid for 1 yr
acute sinusitis
- mcc
- how to tel b/w bacterial and viral
- chronic define timing
VIRAL
s/s < 7 days
-over 7 days + bilateral purulent discharge from nose=bacterial— strep pneumo, h. influ, m. cata
chronic= > 12 weeks
dx for chronic sinusitis
-GS?
XR— plainview— waters view
GS= CT
tx for acute bacterial sinusitis
**only given is s/s dont improve >10 days
tx=5-7 days long
*amox or augmentin
PCN allergic= Doxycycline
MACROLIDES AND BACTRIM NOT RECCOMENDED FOR EMPIRIC TX BC HIGH RATES OF RESISTANCE FOR STREP PNEUMO
kids= amox 10-14 days
tx for chronic sinusitis
3 weeks long duration tx
-augmentin
pcn allergic= clindamycin
single or multiple small shallow ulcers with yellow-gray fibrinoid center with red halo
- what is it
- dx
- tx
apthos ulcer
**only do biopsy if lasting > 3 wks
tx=viscous lido
chronic inflammation of eyelid margins
blepharitis
blepharitis
-causes
seborrhea, staph or strep
**dysfunction of meibomian glands
anterior blepharitis
-affect?
eyelid skin
eyelashes
**staph, or seborhhea
posterior blepharitis
inflamm of meibomian glands— can be infectious or caused by glandular dysfunction
crusting, scaling, red-rimming of eyelide and eyelast flaking, adherent eyelashes, hyperemic lid margins, dandruff-like deposits (scurf) and fibrous scales (collarettes); clear or slightly injected conjunctiva; thick cloudy discharge visible when Meibomian glands obstructed
blepharitis
tx for blepharitis
warm compress
daily lid wash with baby shampoo
lid massge to express gland
refractory:
topical abx—Azithromcin, Erythromycin, Bacitrain
painless otorrhea, brown/yellow discharge with a strong odor
*hearing loss
cholesteatoma
**hearing loss is on affected side— conductive
tx for cholesteatoma in office
remove with silver nitrate sticks
topical Ciprofloxacin and Dexamethasoe drops or PO cipro or Bactrim
MC virus causing conjucntiitis
adenovirus
mc bacteria conjuncitivits
staph aureus
s/s for viral conjunctivitis
BILATERAL
FB sensation
clear watery dsx
enlarged preauricular lymph node
s/s for bacterial conjunctiitis
unilateral at first– but then can spread
eye glued shut
opthalmia neonatorum
gonococcal infection of neonate within 2-5 days delivery
** mc chlamydia if > days s/s develop
tx for bacterial conjuncitiits
topical gentamycin/tobramycin (Tobrex) **
contact wearer: topical ciprofloxacin to cover pseudo
Erythromycin oinemnt for chlamydia newborns
*systemic tetracycline or erythromycin
Gonorrhea— prompt referral + systemic ABX
tx for allergic conjuncitivitis
epinastine (Elestat)
azelastine (Optivar)
Emedastine difumarate (Emadine)
Levocabastine (Livostin)
Sudden onset of eye pain, photophobia, tearing, foreign body sensation, blurring of vision, and/or conjunctival injection
corneal abrasion
corneal abrasion
- RF
- diagnosis
RF= contacts, occupations where small things fly around
DX
- prior to lid eversion and staining– use Proparacaine drops for anesthetic
- Flurescein stain— Abrasion will GLOW green/yellow with slit lamp—- see a +Seidel sign– leakage of aqueous fluid showing corneal perforation
- *NO eye patching
tear drop shape pupil— what to order next
CT and emergent optho consult
corneal ulcer aka?
ulcerative keratitis
corneal ulcer
-causes
inflammatory or infective dz of cornea—->disruption of epithelial layer and corneal stroma
FB sensation with increased tear production, sensitivity to light,
+ PAIN and eye redness
corneal ulcer
dendritic lesions seen on slit lamp and fluro staining
herpes simplex keratitis
corneal ulcer tx
- small ulcer
- herpes
- fungal
- pain
- avoid what drug?
immediate referrral
small= Moxifloxacin, tobramycin, Cefazolin, drops
HSV–Trifluridine***, ganciclovir, Valacyclovir, Acyclovir drops,
Fungal–Natamycin**, amphotericin B, Voriconazole drops
PAIN= Atropine or Scopolamine
AVOID CORTICOSTEROIDS bc they prolong healing time
white spot on the surface of the cornea that stains with fluoscene
corneal ulcer
which vit deficiency can be assoc with corneal ulcer
A
inflammation of the nasolacrimal duct or nasolacrimal gland
dacroadenitis
dacroadenitis
rapid onset
unilateral severe pain, redness and pressure
in the SUPRATEMPORAL region—- above the top eyelid
Dacrocystitis
infectious obstruction of nasolacrimal duct
rapid onset
unilateral, severe pain, redness and EPIPHORA– overflow of tears
INFRAMEDIAL REGION
MC staph aureus
excessive tears, blurry vision, inflammation to medial canthal of lower lid
dacrocystitis
dacrocystitis
- dx
- tx
DX
- Schirmer basic secretor test– tear draininage test
- Irrigation and probing–help relieve blockage (diagnostic and therapeutic)
- jones dye test– looks for anatomical obstruction
- CT ONLY if orbital cellulitis is suspected
***lacrical massage, dilation, probing, flushing
infectious= Topical abx
- purulent laacrimal sac— augmentin PO
- if orbital cellulitis–> IV abx and hosp admission—– Ampicillin-Sulbactam, Cefrtri, Moxifloxacin
Eversion of eyelid— turning outward
- define
- tx
ectropion
tx— tear supplements, ocular lurbicants– surgery=definitive
Inversion of eyelid—- eyelid turning inward
- define
- tx
entropion
tx— tear supplements, ocular lurbicants– surgery=definitive
palsy of which CN can cause ectropion
CN VII— facial nerve
what can you use to help vasoconstrict nares during epistaxis
Oxymetazoline aka Afrin +/- lidocaine
can also try topical sympathomimetics like Phenylephrine
packing the nose for >72 hrs and/or pt is immunocomp, what else do we give
Augmentin or Cefuroxime prophylaxis
severe eye pain, HA, N/V
acute narrow angle closure glaucoma
gradual peripheral vision loss
GLAUCOMA
central vision loss
MAC DEGEN
injected conjunctiva, steamy cornea, and fixed dilated pupil,
acute glaucoma
tx for acute glaucoma
GOAL IS TO DECR IOP IMMEDIATELY
- Acetazolamide IV first line followed by mannitol or Isosorbide
- Pilocarpine or timolol
- Carbonic anhydrase— Diamox
DEFINITIVE= laser peripheral iridotommy
tx for chronic glaucoma
- Lanatoprost, Tafluprost or Timolol drops
painful, warm, swollen red lump on eyelid
hordeolum
hard non-tender mass on eyelid
chalazion
blood in anterior chamber seen with penlight
hyphema
tx for hyphema
**blood is reasbored within days-weeks
1 metal eye shield to prevent incr IOP 2. elevate head of bed to 30-40 degrees 3. emergent optho ref 4 ,timolol or brimonidine to decr IOP 5. Atropine or Scopolamine to dilate eyes