FM 2 Flashcards
define cardiac chest pain that that occurs at rest and usually happens at night or early morning hours
printzmetal or vasospastic
gold standard to diagnose printzmetal angina
coronary angiography with the injection of provocative agents into the coronary artery.
tx for prinzmetal angina
nitro and CCB***
what medication is contraindicated for printzmetal angina
BB
Early wide “bizarre” QRS, no p wave seen
PVC
NSTEMI
ECG changes such as ST-segment depression, T-wave inversion, or both may be present, cardiac markers will be elevated
pericarditis cp is relieved with?
sitting and/or leaning forward
best initial test for PE
spiral CT
triangular or rounded pleural-based infiltrate usually located adjacent to the hilum
estermark sign or Hampton hump
**PE
gold standard definitive test for diagnosis of PE
Pulmonary angiography
S4 heart sounds
Diastolic HF (ejection fraction is usually normal)
S3 heart sound
Systolic HF (reduced EF) with volume overload - tachycardia, tachypnea. (Rapid ventricular filling during early diastole is the mechanism responsible for the S3)
best test to diagnose CHF
echo
Systolic left heart failure tx
ACEI + loop diuretic + BB
Diastolic heart failure tx
Ace inhibitor + β-blocker or CCB
(**(do not use diuretics in stable chronic diastolic failure)
what murmur do you MC hear with CAD
mitral regurg an S4
BP under what for prevention of CAD
<140/90
want LDL levels under?
<70
ASA allergy.. waht to prescribe for MI Prevention
clopidogrel
dental or medical procedures in the mouth, intestinal tract or urinary tract
want to think?
endocarditis
fever + new onset murmur
endocarditis
MCC of ndocarditis with intravenous drug users
staph aureus
MCC Of Endocarditis with prosthetic valve
staph epidermitis
emperic tx for endocarditis
-what if they have prosthetic vavle?
IV vancomycin or ampicillin/sulbactam PLUS aminoglycoside
prosthetic valve—– add rifampin
High-Risk patients endocarditis prophylaxis for procedures give?
Amoxicillin - 2 g 30-60 minutes before the procedure
SPSTF recommends screening for patients for hyperlipidemia with NO evidence of CVD and NO other risk factors should begin at _______years of age
35
NCEP recommends screening all adults for hyperlipidemia at age _____years regardless of risk factors
20
FOUR GROUPS MOST LIKELY TO BENEFIT FROM STATIN THERAPY
- Patients with any form of clinical atherosclerotic cardiovascular disease (ASCVD)
- Patients with primary LDL-C levels of 190 mg per dL or greater
- Patients WITH diabetes mellitus, 40 to 75 years of age, with LDL-C levels of 70 to 189 mg per dL
- patients WITHOUT diabetes, 40 to 75 years of age, with an estimated 10-year ASCVD risk ≥ 7.5%
HDL level of ___ is protective
> 60
list the high intensitty drugs given for hyperlipidemia
Atorvastatin 40-80 mg
Rosuvastatin 40 mg
Primary hypertension is defined as
resting systolic BP ≥ 130 or diastolic BP ≥ 80
- on at least two readings
- on at least two separate visits
- with no identifiable cause
BP
- normal
- elevated
- stage 1
- stage 2
NORMAL: <120/80 and <80
ELEVATED: 120-129 and <80
STAGE 1: 130-139 OR 8-89
STAGE 2: >140 OR >90
target BP
<130/80
treatment guidelines for BP of:
- normal
- elev
- stage 1
- stage 2
NORMAL: eveal in 1 year, encourge healthy lifestyle
ELEV: Recommend healthy lifestyle changes and reassess in 3-6 months
STAGE 1:
- assess 10 yr risk
- *If risk < 10% start healthy lifestyle management and reassess in 3-6 months
- *If risk > 10% or CVD, DM, CKD - lifestyle mod + 1 medication - reassess in 1 month
- —->If goal met after 1 month - reassess in 3-6 months
- —-> if goal not met after 1 MO— diff med or titrate current med
STAGE 2: healthy lifestyle + 2 BP meds
- *If goal met after 1 month - reassess in 3-6 months
- *If goal not met after 1 month, consider different med or titrate
HTN
For NON-BLACK patients, including those with diabetes: Initial treatment should be with either:
ACEI Or ARB
or
Long-acting calcium channel blockers (most often a dihydropyridine such as amlodipine)
or a thiazide-like diuretic (chlorthalidone or indapamide)
two meds that are most effective for HTN in black pt
thiazides and CCB
HTN MEDS FOR THE DISEASE
1. angina pectoris
- CCB
2.
tx for acute coronary syndrome
M O N A ACEI
what is malignant HTN
-tx? **
Diastolic reading > 140 associated with papilledema (stage iv emergency) and either encephalopathy or nephropathy
TX
1. hydralazine IV
-prils
ACEI
-sartans
ARBs
Nifedipine
Dihydroperidine CCB
Amlodipine
Dihydroperidine CCB
-pines
Dihydroperidine CCB
Diltiazem
non Dihydroperidine CCB
Verapamil
non
Dihydroperidine CCB
-zosins
alpha blockers
A-M BBs are?
cardioselective— act only on B1
- atenolol
- metoprool
- Esmolol
- bismolol
N-Z BBs are?
non cardio selective --act on B1 and B2 *Nadolol *Propranolol *Timolol *Sotalol (pindolol
list alpha and beta BBs
Labetalol
Carvediolol
HTN in pregnancy tx?
Hydralazine*
labetalol
nicardipine
Methyldopa
HTN + AFIB tx?
BB or CCB (non dihydroperidne … verap or diltizame)
Angina + HTN tx
BB or CCB
POST MI + HTN tx
BB or ACEI
Systolic HF + HTN tx
ACEI, BB, ARB, Diuretics
DM/CKD + HTN tx
ACEI, ARB
Osteoporosis + HTN
thiazides
AA + HTN
CCB or diuretics thiazides
first line tx for intermittent claudication aka periph arterial disease
smoking cessation
other lines of tx for intermttent claudication
graduated exerise—walk to the point of claudication, then rest, then continue etc
control HTN DM weight
ASA + clopidogrel
Cilostazol (vasodilator)
tx for asymptomatic PAD
preventative measures:
- ASA
- lipid lowering agents
- bp control
tx for PAD
- prevention of atherosclerosis—control HLD, HTN, weight, DM
- manage hyperlipidemia—statins, diet, exercise
graduated exercise
reduce BP
stop smoking
-
**MEDICAL INTERVENTION MOST IMP
1. ASA + ticlopidine or clopidogrel—- symptomatic relief
2. Cilostazol (PDE inhib aka vasodilator)***
diagnosis for PAD
ABI <0.9
-definitive=arteriography
first line tx for PVD
elevation and use of compression stockings
S4, LVH,
young male who passes out during sports
HOCM
Medium-pitched, mid-systolic murmur that decreases with squatting and increases with straining or valsalva
HOCM
mcc CHF
CAD
HTN
MI
DM
left sided HF s/s
pulmonary symps—- dyspna MC, orthopnea (LATE finding), pulm congestion/rales, pink frothy sputum, transudative effusions**
right sided HF s/s
backs up into periphery *periph edema, pitting edema hepatic congestion, fatigue abd bloating anorexia
cxr findings for chf
kerley b lines–white markings in periphery
butterly or batwing apperance–pulm wedge pressure 12-18 hhmg
pulm edema and or plerual effusion–perihilar congestion
peri bronchial cuffing
cardiomegaly
meds that a pt with CAD need to be on/discharged on from hosptial
ASA
SL nitro prn
dialy BB
high intensity statin
+/- ACEI (if LV function impaired)
what valve is MC invovled in endocarditis
mitral
mc bug causing acute bacterial endocarditis with normal valves
streph aureus
MC valves invovled in bac endocarditis
in order of mc to least mc
mitral–mc
arotic 2nd mc
tricuspid 3rd mc
pulmonic 4th mc
subacute bac endocarditis mc bug
strep viridans— less virulent why its subacute and is an indolent infection
MC from oral infection**
IV drug user endocarditis mc bugs
MRSA
staph aureus
pseudomonas
candidida
prosthetic valvues endocarditis mc bugs
staph epidermidis
mc bug to cause endocarditis after valve surgery
candida
MCC OVERALL of endocarditis
streptococcus viridans
acute endocarditis with native valve and not IVDU
ampicillin + Nafcillin + gentamicin
or
Vancomycin + gentamycin for mRSA
pt with prosthetic valve who have endocarditis tx
vanco + gentamicin + rifampin
IVDU endocarditis
nafcillin or vanco
subacute endocarditis with native valve tx
pencillin or ampicillin + gentamycin
fungal ednocarditis tx
amphotericin B and usually surgery
indications for abx prophylaxis b4 oral procedures
and DOC and alternatives
cardiac
- prosthetic valve or any prosthetic inserts like stents
- prior hx of endocarditis
- congen heart dz
- cardio valvuloplasty in transplanted heart
DOC= 2g amoxicillin 30-60 min b4
Clindamycin is allergic
ACEI and pregnancy
CONTRAINDICATED
SE: cough, angioedema, hyperK
list rate control CCBs
verpamil and diltiazem
hydralazine can cause
lupus like syndrome and pericarditis
tx
- htn emergency
- htn urgency
- malig htn
emergency= sodium nitroprusside DOC
urgency= clonidine DOC
malignant=hydralazine
tx for isolated hypertriglyceridiemia
Fibrates—- Gemfibrozil and Fenofibrate
and
Niacin
***statins not used alone for this
se of niacin
hyperglycemia— caution with DM
flushing
incr in LFTs
SE of fibrates
rhabdo–esp with Gemfibrozil + statin combo
SE of statins
myopathy
rhabdo
incr in LFTs