Flukes Flashcards
Describe the life cycle of Schistosoma mansonii
Free-swimming larvae in fresh water penetrate skin and enter circulation
Migrates to portal blood in liver, matures
Migrate to mesenteric venules of bowel/rectum and venous plexus of bladder
Shed in faeces
Infects freshwater snails
What are some of the possible long term sequelae of infection with Schistosoma?
Dermatitis or asymptomatic in light infections
Heavy infections can cause hepatosplenomegaly and portal hypertension
How is infection with Schistosoma diagnosed?
Eggs in faeces on wet mount
Serology
How is infection with Schistosoma treated?
Anti-helminthic
How is Schistosoma prevented?
Molluscacides
Sanitary disposal of sewage
Treatment of carriers
What kind of immune response is mounted to Schistosoma?
Weak (chronic and repeated infections are common)
Where is Schistosoma found?
Africa, South America, Caribbean