Fluids + Electrolytes Pt 1 Flashcards
Homeostasis
Volume + composition of each space remains constant
What can impact homeostasis?
- vomiting
- diarrhea
- ace inhibitors
- diuretics
Amount of plasma in the body
- Plasma: 3L
- Interstitial fluid (IF): 10L
- Intracellular fluid (ICF): 28L
Composition of body fluids
-Water
- Primary component of body
- Accounts for approx 60% of body wt
- Adequate balance is necessary for
-maintenance of temp
-elimination of waste products
-all transportation within body
Factors that affect body water
Age is a huge factor:
* neonates are made of 80% water
* older adults are made of 45% water
Other factors that influence body water:
* The more adipose tissue the less body water you have.
* The more muscle mass you have the more body water you have.
Composition of body fluids
-Solutes
- Electrolytes: Chemical compounds that develop an ionic charge when dissolved in water
- All body fluids contain electrolytes
Regulation of electrolyte levels is critical for:
- maintenance of body fluid osmolality
- acid balance
- neuromuscular function
- cell metabolism
Composition of body fluids
-Nonelectrolytes
- do not dissociate in solution
- measured by wt
- Glucose - Urea - Creatinine - Bilirubin - Proteins
Body fluid compartment
-Transcellular fluids (not subject to significant gains or losses)
- CSF
- GI tract
- Pleural
- Synovial
- Peritoneal
First spacing?
Normal distribution of fluid
Second spacing?
Abnormal accumulation of interstitial fluid
Third spacing?
- Abnormal accumulation in areas that have no or little amt of fluid
- Fluid unavailable for use
Movement of body fluids
-What is it?
- Fluid constantly moves among intracellular, interstitial and vascular spaces to maintain body fluid balance
- Moves through permeable membranes
-permits movement of water + some solutes - Normally ICF + ECF are isotonic w/ each other
Osmosis?
- Osmosis stops when equilibrium is reached
- Major force in body fluid movement
- Important to consider w/ IV therapy
Movement of body fluids
-Osmotic pressure
- Refers to pulling power of a solution for water
- The higher the osmolality of a solution greater pulling power for water
Movement of body fluids
-Oncotic pressure
Refers to pulling force exerted by colloids
Movement of body fluids
-Diffusion
Solute moves from area of higher concentration to area of lower concentration until equilibrium.
“coasting downhill”