Fluid Compartment

Question 1

What is the tissue preservation solution for organ transplant?

Answer 1

Machine perfusion with UW (university of Wisconsin) solution

Question 2

What does UW (university of Wisconsin) solution do and how ?

Answer 2

Reduce cell swelling.
Lack of Na+/Cl-
Has extracellular impermeant solutes.
Has macromolecular colloid (starch)
Has antioxidants

Question 3

Name the anti oxidants in UW solution. And what is the highest conc in the solution

Answer 3

Anti oxidant: allopurinol, glutathione.
Highest conc: potassium lactobionate

Question 4

What passes through endothelial cells

Answer 4

Lipid-soluble substances

Question 5

What passes through pores between cells

Answer 5

Small water-soluble substances

Question 6

What passes through by vesicular transport

Answer 6

Exchangeable proteins

Question 7

Types of oedema?

Answer 7

Inflammatory (insect bites)
Hydrostatic (overweight/old age/high BP)

Question 8

Oedema from compromised lymphatic function

Answer 8

Breast cancer - axillary lymph node removed- accumulation of fluid in arm.
Elephantiasis - parasite block note- cannot drain- in leg