Blood Transfusion- Components

Question 1

Packed red cells:
shelf life and storage?
Use?

Answer 1

shelf life 35 days
storage fridge 4 degrees Celsius
Use: anaemia, haemorrhage

Question 2

Platelets:

shelf life and storage?
Use?

Answer 2

shelf life- 7 days
storage- room temp. Need constant agitation to ensure they are constantly oxygenated.
Use: reduce risk of bleeding. Ensure ABO group match.

Question 3

Fresh frozen plasma
shelf life and storage?
Use?

Answer 3

shelf life- 3 years
storage: -25 degrees Celsius
Use- reduce risk of bleeding/multiple clotting factor deficiencies.
Transfusion: thawed in water bath-> Stored at 4 degrees Celsius, used within 24 hrs.

Question 4

Cryoprecipitate
shelf life and storage?
Use?

Answer 4

shelf life- 3 years
storage: -25 degrees Celsius.
Transfusion: thawed in water bath-> stored at room temperature and use within 4HRS.
Use: reduce risk of bleeding when FIBRINOGEN is low (from major haemorrhage/DIC)

Question 5

How is cryoprecipitate is made?

Answer 5

Slow thawing of FFP overnight until there is precipitate. Precipitate suspended in small volume of plasma and frozen to maintain activity of clotting factors

Question 6

Plasma-derived medicinal products
What are they

Answer 6

Human albumin solution,
Ig solution
Clotting factor concentrates

Question 7

HAS?

Answer 7

Replace plasma volume when it is lost from trauma

Question 8

What does cryoprecipitate have

Answer 8

VWF
Fibrinogen
Factor 8, 13

Question 9

What does FFP Contain

Answer 9

All coagulation factors - to treat prolonged PT/APTT