Fluid and electrolytes, Kidney Disease and Dialysis Flashcards
Hypovolemia and how to treat it
> 5% weight loss, decreased skin turgor, dry mucous membranes, low BP, increased Hg/HCT, decreased UOP, Elevated Na, Increased SG
Treatment includes IV fluids + NSS
Hypervolemia and how to treat it
> 5% weight gain, edema, crackles, SOB, JVD, decreased Hg/HCT, Decreased Na, Decreased SG
Treatment includes diuretics, fluid restriction, salt restriction, dialysis
Hyponatremia and how to treat it
nausea, lethargy, change in mental status, headache, seizures
Treat with NSS/ Hypertonic saline (fluid overload- diuretics)
Hypernatremia and how to treat it
Thirst, dry mucous membranes, weakness, change in mental status
Treatment includes sodium restriction, increasing fluids, change in mental status
Hypokalemia and how to treat it
muscle weakness/ cramping, EKG changes, lethargy
Treatment includes oral/ IV replacement, dietary supplementation
Hyperkalemia and how to treat it
Nausea and diarrhea, muscle weakness, EKG changes
Treatment includes Kayexalate, diuretics, IV insulin and glucose, calcium chloride, sodium bicarb, dialysis
AKI
sudden and rapid loss of renal function (decreased blood flow, nephrotoxicity, obstruction)
AKI characteristics + goals of treatment
increased creatine, decreased GFR, azotemia, oliguria
Goals of treatment include minimizing risk of lethal and long-term complications
Azotemia
increased BUN
Prerenal- definition and causes
decreased blood flow, caused by hypoperfusion, hypovolemia, dehydration, GI losses, hemorrhage, hypotension, low CO, sepsis, burns, thrombosis
Intrarenal- definition and causes
damage to nephrons, caused by ATN, rhabdomyolysis, nephrotoxic meds, IV contrast, autoimmunes, infection
Postrenal- definition and causes
obstruction of urine flow, caused by renal calculi, strictures, thrombus, BPH, prostate cancer, bladder cancer, trauma to strictures
4 Phases of AKI
Initiation, oliguria, diuresis, recovery
Symptoms of AKI
Lethargy, Weakness, Headache, Muscle twitching, Tremor, possible seizures, Nausea, vomiting, anorexia, SOB, pulmonary edema, HTN, Dysrhythmia
Assessment of AKI
elevated BUN and crea, decreased GFR, hematuria, low SG, hyperkalemia, hyperphosphatemia, anemia, metabolic acidosis
AKI management
eliminate underlying cause, optimize renal perfusion (fluids and dopamine), maintain fluid balance (fluids and diuretics), correct chemical abnormalities (fluids, diuretics, dialysis), minimize further risk
AKI monitoring
fluid balance, daily weight, I&O, IV fluids, electrolyte balances
AKI assessing
edema, lung sounds, JVD, HR and rhythm, EKG
AKI prevent
infection, hyperkalemia, fluid volume overload, CKD
AKI pt ed
disease process, diagnostic testing, meds and treatments, self-care, follow up
Glomerulonephritis
acute inflammation of glomerular capillaries, 2nd to strep A, Epstein Barr, varicella, Hep B, HIV
AB antigen complexes deposit in glomeruli, may progress to CKD
symptoms of GN
hematuria, edema, decreased UOP, elevated BUN & creat, HTN, flank pain (cola colored urine)
treatment of GN
steroids, control HTN, treatment of infection, dietary protein restriction w/ increase in carbs
CKD definition
decreasd GFR >3 months, decreased quality of life, may progress to ESRD, significantly increases risk of CV disease
CKD risk factors
HTN, diabetes, cv disease, obesity, 60+, family history, use of nephrotoxic drugs, african americans
CKD Causes
Diabetes, HTN, chronic GN, PCKD, hereditary diseases, congenital diseases, renal artery stenosis/ thrombosis, cancer, nephrotoxic agents
Diabetic nephropathy
Glomerular damage & enlargement
Kidney filtration decreased due to
hyperglycemia
Blood proteins leak into urine
Affects afferent & efferent arterioles
Affects 30% of diabetics
Kidney disease is reduced when glucose levels are controlled
People at high risk for diabetic nephropathy
african americans, native americans and hispanics with T2DM
Diabetic nephropathy assessment
proteinuria, anasarca, HTN, acidosis
Diabetic nephropathy treatment
Control HTN
* Ace Inhibitors
* ARB’s
* Calcium channel blockers
* Eat moderate amount of protein
* high quality
* Low sodium & potassium diet
* Control HgAIC
Nephrosclerosis
hardening of renal arteries, secondary to HTN and diabetes (decreased renal blood flow) major cause of CRF