Fluid Flashcards
How much of our body composed of water
60%
Makes body weight sensitive to fluid status
3 spaces within the ECF
Interstitial (around cell out of vessel)
Intravascular (in BVs)
Transcellular (third spacing)
The proper distribution of water among body compartments is strongly related to what?
The number of osmoles present in the ECF
Osmoles
Drawl water into its direction
Normal concentration of osmoles in the ECF is
275-295
How do we assess fluid and electrolyte status?
Blood sample
Test the liquid components of blood (plasma and serum)
Plasma
Liquid component of blood
Plasma proteins and all other particles dissolved in the blood
Serum
Liquid component of blood
Remains in the blood sample after a blood clot is allowed to form
Does not contain:
The coagulation proteins used to form the clot
Does contain :
-Other plasma proteins (antibodies, hormones)
-Dissolved particles (glucose, electrolytes, O2 & CO2)
Osmolarity vs osmolality
Osmolarity: miliosmoles per liter (IV solutions)
Osmolality: milliosmoles per Kilogram (human body)
Osmosis
Movement of water across a semipermeable membrane
Plasma membranes of cells are:
Freely permeable to water
Relatively impermeable to sodium
When osmolality is off look at what three things
Na
Glucose
BUN
Normal serum sodium
140
Sodium x 2 = osmolality (140x2=280)
Isotonic
Same as normal, healthy plasma
Normal osmolality=275-295
Hypotonic
ECF tonicity too low
Swells cell
Hypertonic
ECF tonicity too high
Cell shrinks