Flaccid Dysarthria Flashcards
What are speech characteristics of flaccid dysarthria?
monopitch; monoloudness; audible inspiration; nasal emission; imprecise consonant production; breathiness; hypernasality; harsh voice; short phrases
What causes flaccid dysarthriaS?
LMN damage
What are LMNs?
motor neurons that send information from the UMN to the muscles; they originate in the brain stem and spinal cord
What are the main clinical characteristics of LMN damage?
hypotonia; weakness of movements; diminished reflexes
What is the most common etiology of flaccid dysarthrias?
Degenerative diseases (e.g., ALS, MS)
What are causes of motor neuron disorders that affect the cell body?
stroke; tumor; degenerative disease; viral infection (poliomyelitis)
Which degenerative disease affects the spinal lower motor neurons?
progressive (spinal) muscular atrophy
Which degenerative disease affects the cranial lower motor neurons?
progressive bulbar palsy
Which degenerative disease affects both UMNs and LMNs?
ALS (Amylotropic Lateral Sclerosis)
What are the symptoms of a nerve cell body disorder?
fasciculations, atrophy, weakness, reduced or lost reflexes, reduced muscle tone
What is a peripheral nerve disorder?
disorder affecting the axons and myelin of the peripheral nerve
What are causes of a peripheral nerve disorder?
nutritional issues (e.g., alcoholism and vitamin deficiency); carcinomas; trauma; immunologic diseases (e.g., HIV, lyme, and leprosy); genetic disease; metabolic diseases (e.g., diabetes and hypothyroidism) ; toxins (e.g., lead and mercury) ; drugs (nitrous oxide)
What are clinical symptoms of a peripheral nerve disorder?
sensory loss and no fasciculations
What are clinical symptoms of a muscle disorder?
weakness, atrophy, and myotonia (cannot relax a muscle after contracting it)
What type of disorder is myasthenia gravis?
a neuromuscular junction disorder that affects postsynaptic processes
What is a neuromuscular junction disorder?
a disorder that affects pre or post-synaptic processes
What are causes of a neuromuscular junction disorder?
autoimmune disorders and toxins
An autoimmune disorder that disrupts presynaptic processes and causes NMJ disorder is
Eaton-Lambert disease
A toxin that affects presynaptic processes and causes NMJ disorder is
botulinum
A toxin that affects postsynaptic processes and causes NMJ disorder is
snake venom
What is myasthenia gravis?
an autoimmune disorder which destroys Ach receptors; thus muscles contract less because they do not have enough receptors for Ach to bind to