First Aid Pediatrics p390 - 399

Question 1

How is Bruton agammablobulinemia diff from Common variable immunodeficiency?

Answer 1

1. Onset of symptoms
   Bruton usually start have symptoms after 6 month of age, whereas in CVID symptoms usually present later in life 15-35 yrs.
2. In Bruton, on B cells are affected, whereas in CVID T cells are affected too.

Question 2

What kinds of infections should you especially worry about in Bruton agammaglobulinemia?

Answer 2

Encapsulated Pseudomonas, Strep pneumoniae, Haemophilus infection after 6 months

Question 3

What kinds of infections should you especially worry about in CVID?

Answer 3

Pyogenic upper and lower reps infections