final study guide Flashcards
Definition of biocultural environmental approach
interrelationship/interaction between human biology (genetics),
culture, and natural environment
e.g. Agricultural Revolution—approx. 12,000 yrs.
interactions between genetics, culture, and natural environment
Scientific Method
Question, Research, Hypothesis, Experiment, Data Analysis, Conclusion, and Communication.
define biocultural/environmental interaction
Recognize the pervasiveness and dynamism of interactions between biological and cultural phenomena
EX. sickle cell anemia
Physical Anthropology
The branch of anthropology concerned with the study of human biological and physiological characteristics and their development.
EX> study of the human body
Catastrophism (Cuvier)
Belief in sudden event that wiped out all prehistoric animals
Carolus Linnaeus
Father of taxonomy- classifying animals according to morphological similarities & differences.
Thomas Malthus
-believed in struggle for survival
-population increases faster than food supply
-helped Darwin develop his theory of natural selection
Jean Baptiste Lamarck
environment is important to adaptation, evolving into complexity
-spontaneous generation
-supported evolution by law of inheritance of acquired characteristics
Uniformitarianism (Lyell)
Natural forces that occur in the past are still occurring today
DNA(Watson, Crick, Franklin)
They discovered the structure of nuclear DNA (nDMNA) discovery (20th century)
1962 Nobel Prize- James Watson, Francis Crick & Maurice Wilkins
they realized that DNA was made up of two chains of nucleotide pairs that encode the genetic information for all living things.
Darwin & Natural Selection; Wallace
if an animal has some trait that helps it to withstand the elements or to breed more successfully, it may leave more offspring behind than others.
Reproductive Fitness
The reproductive fitness reflects the potential of an individual to pass on its genes to the subsequent generations.
Mendelian genetics
explains the underlying mechanism
of how simple traits (at a single locus) are inherited
Mendel
discovered the basic principles of heredity and laid the mathematical foundation of the science of genetics. (genes do not blend)
Recessive
Recessive is a trait that is expressed only when genotype is homozygous. (both parents have the same trait but is recessive.
Dominance
Trait is always expressed
Homozygotes Dominant
a genotype where an individual inherits two copies of a dominant gene.
Alleles
Alternate forms of a gene
Mendelian Laws
the Law of Dominance and Uniformity, the Law of Segregation, and the Law of Independent Assortment
Law of segregation
every trait has two discrete particles one
inherited from the mother and one from the father
law of independent assortment
the inheritance of one trait does not affect the
inheritance of other traits
DNA discovery
Adenine and Guanine
are purines
*Thymine and Cytosine
are pyrimidines
Adenine always pairs with thymine
cytosine pairs with guanine
Heterozygotes Dominant
the dominant allele overrules the recessive one.
Homozygous Recessive
homozygous recessive, if it carries two copies of the same recessive allele.
Mitochondria DNA mtDNA (bones)
Circular DNA molecule: 16,569 base pairs in length (37 coding genes) small genome. found inside cellular organelles called mitochondria
Chromosomes
Strands of DNA containing thousands of genes
Explanation: They pass down the DNA from parents to offspring.
Somatic Cells (diploid)
The somatic cells are any cells besides the sex cells
Gametes (haploid)
Sex cells
Mitosis
production of identical body cells (adult cells) for example. Skin, kidney, heart, muscle, etc. the repair after surgery.
Explanation: mitosis is the repair of body cells after surgery or accident
Meiosis
meiosis is the cell division that produces sex cells (gametes)
ABO Blood System
Antigens: proteins on surface of cell—identifies the cell; foreign antigens can cause an immune reaction
Antibodies (immunoglobulins): important cells in the immune system—they bind to foreign antigens
Locus
Location of a gene on the chromosome
(loci [plural] several genes on a chromosome)
Genetics and Heredity
Disease history
Distribution of blood type may be related to disease,
natural selection and survival in human history
EX.
South America: Indigenous populations—100% ‘O’
blood type. WHY?
syphilis The bacteria that cause syphilis is
biochemically similar to ‘A’ molecules (A blood type)
(‘O’ has anti-A antibodies)
Euroasia—high frequency of ‘B’ blood type (lower
frequencies of ‘A’ and ‘O’. WHY?
History: smallpox and bubonic plague in Euroasia
Blood type ‘A’ individuals susceptible to smallpox
Blood type ‘O’ individuals susceptible to bubonic
plague
*While the ‘A’ and ‘O’ individuals are dying, the
individuals with ‘B’ blood type are thriving
Rhesus Blood Group
Rh-induced hemolytic disease: and Selection Against the Heterozygote
Rh-positive (DD Dd) *protein (antigen) is present on RBC
Rh-negative (dd) *protein (antigen) is not present on RBC
Rh factor: a protein on the surface of RBCs.
If mother is Rh-negative (dd) and father is Rh-positive
(DD), the infant will be Rh-positive (Dd). This leads to
Rhesus incompatibility where the mother’s immune
system will view the fetal RBCs as foreign material and
subsequently generate anti-D antibodies to destroy them.
severe anemia & jaundice in offspring
Polygenic
a characteristic, such as height or skin color, that is influenced by two or more genes.
Pleiotropic
a single gene affects two or more characters.
Regulatory Gene
a gene that regulates the expression of one or more structural genes by controlling the production of a protein (as a genetic repressor) which regulates their rate of transcription
Population genetic
the study of genetic variation within and among populations and the evolutionary factors that explain this variation.
Gene pool
the combination of all the genes (including alleles) present in a reproducing population or species
Point Mutation
Random change of one of the nucleotide base to another
*thymine becomes uracil during protein synthesis
Genetic drift
Random change in allele frequency from one generation
to the next
*Variation in the relative frequency of different genotypes in a small population, owing to the chance disappearance of particular genes as individuals die or do not reproduce.
one population
Founder effect
a few individuals from a population start a new population with a different allele frequency than the original population
Malaria
An intermittent and remittent fever caused by a protozoan parasite that invades the red blood cells. The parasite is transmitted by mosquitoes in many tropical and subtropical regions.
Sickle cell gene
A genetic disorder caused by a mutation in both copies of a person’s HBB gene.
Tuberculosis
an infectious bacterial disease characterized by the growth of nodules (tubercles) in the tissues, especially the lungs.
Typhoid
an infectious bacterial fever with an eruption of red spots on the chest and abdomen and severe intestinal irritation
*Heterozygotes have higher survival rates in tuberculosis and
typhoid environments