final on selenium Flashcards
1
Q
content of selenium varies in?
A
soil concentration
- certain part of china , denmark and new zealand
2
Q
sources
A
tends to follow Se content in soil cereals and grains dairy fruits veggies organ meat oysters
3
Q
enzymes containing Se?
A
glutathione peroxidase (antioxidant system) thyronine deiodinase (activate T3 & T4) thioredoxin reducase (transport system for Se)
4
Q
2 functions?
A
part of antioxidant enzyme
&
thyroid metabolism, immune function
5
Q
how is it apart of antioxidant enzymes?
A
part of GPx - it removes H2O2, LOOH and ROOH - uses GSH as substrate - regeneration of GSH from GSSG overlaps with vitamin E and reacts with it to protect cells
6
Q
deficiency disease?
A
regional disease in china keshan disease = cardiomyopathy (heart failure) kashin beck's disease = osteoarthropathy with degeneration of joints
7
Q
people on total parenteral nutrition deficiency?
A
poor growth
muscle pain and weakness
8
Q
RDA?
UL?
A
55 ug
400 ug
9
Q
toxicity symptoms?
A
nausea vomiting fatigue diarrhea hair and nail brittleness lethal with acute poisoning
10
Q
food sources?
A
brazil nuts
shrimp
crab meat
salmon
11
Q
cancer prevention?
A
prevents prostate cancer
