final exam drugs Flashcards
Cosyntropin
Hyperadrenocorticism diagnosis (ACTH stim test)
Dexamethasone
Hyperadrenocorticism diagnosis - suppresses ACTH and CRH, should decrease cortisol
Trilostane
- DOC for small animals in neoplastic hyperadrenocorticism treatment
- competitive inhibitor of 3B-hydroxysteroid dehydrogenase
Mitotane
- neoplastic hyperadrenocorticism treatment
- destroys zona reticularis & zona fasciculata
pergolide mesylate
treats equine cushings (PPID)
dopamine receptor agonist
dexamethasone
- treatment of bovine ketosis (induces gluconeogenesis)
- abortant
isoflupredone
- treatment of bovine ketosis (induces gluconeogenesis)
- less risk for abortion
- may cause hypokalemia
Glucocorticoid replacement drugs (HPMTDFDA)
- hydrocortisone (cortisol)
- predisone
- methyprednisolone
- triamcinolone
- dexamethasone
- fludrocortisone
- deoxycorticosterone
- aldosterone
Glucocorticoids for inflammatory conditions (BBFI)
- Butamethasone
- Budenosine
- Fluticasone
- Isoflupredone
triamcinolone
- musculoskeletal / joint injection in horses
- systemic and local treatment of integument conitions
isoflupredone
- musculoskeletal / joint injection in swine and cows
flumethasone
- musculoskeletal / joint injection in horse and dogs
methylprednisone & betamethasone
- ELU in musculoskeletal / joint injections
glucocorticoids used in systemic treatment of integument conditison
- Dexamethasone
- Prednisone
- Triamcinolone
glucocorticoids used in topical/local treatment of integument conditison
- hydrocortisone
- isoflupredone
- triamcinolone
what drugs are mineralcorticoids (regulate Na and water balance; Aldosterone)
- Fludrocortisone
- Desoxycorticosterone pivilate
Fludrocortisone
glucocorticoid AND mineralcorticoid (aldosterone) replacement
Desoxycorticosterone pivilate
mineralcorticoid (aldosterone) replacement
slow release
finasteride
- treatment for benign prostatic hyperplasia
- LONG ACTING 16 WKS
- inhibits conversion of testosterone (inactive) into 5α-dihydrotestosterone (alpha) by inhibitng 5α-reductase
Medroxyprogesterone (progestin)
- treatment for benign prostatic hyperplasia
- directly competes w/ active testosterone
- not safe around pregnant women
- temporary inhibition of spermatogenesis
GnRH (males)
- correct cryptorchidism
- determine if testicular remnants
hCG (males)
- correct cryptorchidism
- determine if testicular remnants
- hypersensitivity b/c large protein
GnRH (females)
- treatment of follicular cysts in cows (LU)
- synchronize estrus in cows (LU)
- detect ovarian remnants in cats (ELU)
hCG (females)
- treatment of follicular cysts in cows (LU)
- detect ovarian remnants in dogs
- induce estrus in prepuberal gilts + noncyling sows (LU)
