final exam drugs

Question 1

Cosyntropin

Answer 1

Hyperadrenocorticism diagnosis (ACTH stim test)

Question 2

Dexamethasone

Answer 2

Hyperadrenocorticism diagnosis - suppresses ACTH and CRH, should decrease cortisol

Question 3

Trilostane

Answer 3

• DOC for small animals in neoplastic hyperadrenocorticism treatment
• competitive inhibitor of 3B-hydroxysteroid dehydrogenase

Question 4

Mitotane

Answer 4

• neoplastic hyperadrenocorticism treatment
• destroys zona reticularis & zona fasciculata

Question 5

pergolide mesylate

Answer 5

treats equine cushings (PPID)
dopamine receptor agonist

Question 6

dexamethasone

Answer 6

• treatment of bovine ketosis (induces gluconeogenesis)
• abortant

Question 7

isoflupredone

Answer 7

• treatment of bovine ketosis (induces gluconeogenesis)
• less risk for abortion
• may cause hypokalemia

Question 8

Glucocorticoid replacement drugs (HPMTDFDA)

Answer 8

• hydrocortisone (cortisol)
• predisone
• methyprednisolone
• triamcinolone
• dexamethasone
• fludrocortisone
• deoxycorticosterone
• aldosterone

Question 9

Glucocorticoids for inflammatory conditions (BBFI)

Answer 9

• Butamethasone
• Budenosine
• Fluticasone
• Isoflupredone

Question 10

triamcinolone

Answer 10

• musculoskeletal / joint injection in horses
• systemic and local treatment of integument conitions

Question 11

isoflupredone

Answer 11

• musculoskeletal / joint injection in swine and cows

Question 12

flumethasone

Answer 12

• musculoskeletal / joint injection in horse and dogs

Question 13

methylprednisone & betamethasone

Answer 13

• ELU in musculoskeletal / joint injections

Question 14

glucocorticoids used in systemic treatment of integument conditison

Answer 14

• Dexamethasone
• Prednisone
• Triamcinolone

Question 15

glucocorticoids used in topical/local treatment of integument conditison

Answer 15

• hydrocortisone
• isoflupredone
• triamcinolone

Question 16

what drugs are mineralcorticoids (regulate Na and water balance; Aldosterone)

Answer 16

• Fludrocortisone
• Desoxycorticosterone pivilate

Question 17

Fludrocortisone

Answer 17

glucocorticoid AND mineralcorticoid (aldosterone) replacement

Question 18

Desoxycorticosterone pivilate

Answer 18

mineralcorticoid (aldosterone) replacement
slow release

Question 19

finasteride

Answer 19

• treatment for benign prostatic hyperplasia
• LONG ACTING 16 WKS
• inhibits conversion of testosterone (inactive) into 5α-dihydrotestosterone (alpha) by inhibitng 5α-reductase

Question 20

Medroxyprogesterone (progestin)

Answer 20

• treatment for benign prostatic hyperplasia
• directly competes w/ active testosterone
• not safe around pregnant women
• temporary inhibition of spermatogenesis

Question 21

GnRH (males)

Answer 21

• correct cryptorchidism
• determine if testicular remnants

Question 22

hCG (males)

Answer 22

• correct cryptorchidism
• determine if testicular remnants
• hypersensitivity b/c large protein

Question 23

GnRH (females)

Answer 23

• treatment of follicular cysts in cows (LU)
• synchronize estrus in cows (LU)
• detect ovarian remnants in cats (ELU)

Question 24

hCG (females)

Answer 24

• treatment of follicular cysts in cows (LU)
• detect ovarian remnants in dogs
• induce estrus in prepuberal gilts + noncyling sows (LU)