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Therapeutics P3 Semester 1 > Final Exam - Cancer Drugs MOA > Flashcards

Final Exam - Cancer Drugs MOA Flashcards

1
Q

6-mercaptopurine

A

inhibits purine ring biosynthesis

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2
Q

methotrexate

A

inhibits dihydrofolate reductase
-inhibits thymidine synthesis, biosynthesis of purines and pyrimidines, and protein synthesis

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3
Q

5-flourouracil

A

inhibits thymidylate synthase

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4
Q

cytarabine

A

inihibits DNA synthesis

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5
Q

irinotecan

A

inhibits topo1

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6
Q

doxorubicin

A

inhibits topo2
causes DNA damage

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7
Q

bleomycin

A

inhibits topo2
causes DNA damage

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8
Q

etoposide

A

inhibits topo2

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9
Q

vincristine

A

inhibits microtubules (destabilizer)

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10
Q

paclitaxel

A

inhibits microtubules (stabilizing)

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11
Q

docetaxel

A

inhibits microtubules (stabilizing)

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Therapeutics P3 Semester 1 (22 decks)

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