Final Exam Flashcards
What are the generic parts of a spinal nerve?
- ventral and dorsal nerve rootlets
- ventral and dorsal nerve roots
- dorsal nerve root ganglion
- mixed spinal nerve
- ventral and dorsal primary nerve rami or divisions
What is the name given to the dendrite of a primary sensory neuron?
peripheral sensory process
What parts of the peripheral nerve system will contain peripheral sensory proceses?
- mixed spinal nerve
- ventral primary ramus/division
- dorsal primary ramus/division
What parts of the peripheral nerve system will contain central sensory processes?
- dorsal nerve root
- dorsal nerve rootlets
What are the ultimate target cells of the somatic efferent pathways?
skeletal muscle
What are the ultimate target cells of the visceral efferent pathways?
- smooth muscle
- cardiac muscle
- glandular tissue
- some unique specialized cell types
What cord levels will contain somatic efferent neurons?
cord levels C1-Co1
What skeletal muscles are specifically innervated via dorsal primary rami/divisions?
- splenius
- erector spinae
- transversospinalis
- suboccipital
- interspinalis
- intertransversarii
- levator costarum
What skeletal muscle is innervated via both ventral primary rami/divisions and dorsal primary rami/divisions?
the intertransversarii
Skeletal muscle located on the dorsal side of the extremities will be innervated by which spinal ramus or division branches?
ventral primary ramus/division branches
What are the subdivisions of the visceral division of the peripheral nerve system?
- sympathetic
- parasympathetic
- enteric
What is the location for the enteric nerve system?
along the gastrointestinal tract and organ system
What is the location of the myenteric plexus of Auerbach?
between the longitudinal and circular muscle layers along the entire gut
What function is primarily emphasized for the myenteric plexus of Auerbach?
peristaltic activity along the gastrointestinal tract
What is the location of the submucosal plexus of Meissner?
between the circular muscle layer and the muscularis mucosa layer of the gut
Which enteric plexus lies between the circular muscle layer and the muscularis mucosa layer of the gut?
submucosal plexus of Meissner
What function is primarily emphasized for the submucosal plexus of Meissner?
influence on the process of secretion/absorption of the gut
What locations of the gastrointestinal tract are most influenced by parasympathetics?
the most proximal and distal parts of the gastrointestinal tract
The superior cervical ganglion is the result of fusion of which paravertebral ganglia?
C1-C4 paravertebral ganglia
The middle cervical ganglion is the result of fusion of which paravertebral ganglia?
C5, C6 paravertebral ganglia
The inferior cervical ganglion is the result of fusion of which paravertebral ganglia?
C7-C8 paravertebral ganglia
The stellate ganglion is the result of fusion of which paravertebral ganglia?
C7, C8, T1 paravertebral ganglia
The stellate ganglion will communicate with which spinal nerves?
ventral primary rami of C7, C8, and T1 spinal nerves
Which sympathetic ganglia are located in front of the vertebral body?
prevertebral sympathetic ganglia
What are the names of the most consistent prevertebral ganglia?
- celiac ganglion
- superior mesenteric ganglion
- inferior mesenteric ganglion
Which of the prevertebral nerve plexuses are more likely to contain secondary sympathetic neuron cell bodies?
- cardiac plexus
- pulmonary plexus
- celiac plexus
- inferior hypogastric (pelvic) plexus
How are the remaining nerve plexuses named?
according to the name of the blood vessel they accompany
Based on the target cell innervated, what are the classifications given to postganglionic sympathetic efferent fibers?
- vasomotor fiber
- pilomotor fiber
- sudomotor fiber
- secretomotor fiber
What is the target of postganglionic sympathetic pilomotor fibers?
smooth muscle of hair follicles; the erector pili muscle
What is the target of postganglionic sympathetic sudomotor fibers?
specialized cells of sudorific glands or sweat glands
How are white fibers classified and to what is their color due?
preganglionic sympathetic efferent fibers which are myelinated
Preganglionic sympathetic efferent fibers will bundle together to form what structure which attaches to the paravertebral sympathetic ganglion?
white ramus communicans
Postganglionic sympathetic efferent fibers will bundle together to form what structure which attaches to the paravertebral sympathetic ganglion?
gray ramus communicans
What forms the sympathetic trunk or sympathetic chain?
- interganglionic rami communicans
- paravertebral sympathetic ganglia
What does the splanchnic nerve unite?
paravertebral sympathetic ganglia to the prevertebral sympathetic ganglion
What rami will communicate with the paravertebral ganglia?
- white rami communicans
- gray rami communicans
- interganglionic rami communicans
- splanchnic nerves
What rami or nerves will communicate with prevertebral ganglia?
- splanchnic nerves
- nerves to the target organs (gastric nerve)
Preganglionic sympathetic efferent fibers will pass through what neuronal structures to enter a paravertebral ganglion?
- lateral horn
- ventral horn
- white matter of the cord
- ventral nerve rootlet
- ventral nerve root
- mixed spinal nerve
- ventral primary ramus
- white ramus communicans
- paravertebral ganglion of origin
What is the termination of the horizontal sympathetic neuronal pathway?
- smooth muscle or glandular tissue in the parietal wall of the thorax and upper abdomen
- territory roughly corresponding to the T1-T12, L1-L2 dermatomes
What is the termination of the ascending sympathetic neuronal pathway?
smooth muscle or glandular tissue in the head, neck, and upper extremity
In the ascending pathway, what is the location of synapse of the preganglionic sympathetic efferent fiber?
in a paravertebral ganglion higher than the paravertebral ganglion of origin
List, in order, the pathway of the postganglionic sympathetic efferent fiber of the ascending pathway which synapses on an erector pili muscle on the back of the upper extremity.
- paravertebral ganglion of synapse
- gray ramus communicans
- ventral primary ramus
- synapse on erector pili muscle
What is the termination of the descending sympathetic neuronal pathway?
smooth muscle or glandular tissue in the parietal wall of the lower abdomen, pelvis and lower extremity
In the descending pathway, what is the location of the preganglionic sympathetic efferent fiber?
in a paravertebral ganglion lower than the paravertebral ganglion of origin
Upper and lower extremities are innervated with sympathetics exclusively derived from which ramus or division?
ventral primary ramus
In the splanchnic pathway, what is the location of synapse of the preganglionic sympathetic efferent fiber?
in a prevertebral ganglion or prevertebral plexus
What is the cord level origin of the sympathetic neuronal pathway to the vertebral artery?
upper thoracic spinal cord levels
Where will preganglionic sympathetic efferent fibers synapse in the pathway to the vertebral artery?
inferior cervical ganglion
What is the cord level origin of the sympathetic neuronal pathway to the head?
upper thoracic spinal cord levels T1-T2 typically
Where will preganglionic sympathetic efferent fibers synapse in the pathway to the head?
superior cervical ganglion
What is the cord level origin of the sympathetic neuronal pathway to the heart?
thoracic spinal cord levels T1-T4, T5
Where will preganglionic sympathetic efferent fibers synapse in the pathway to the heart?
1) paravertebral ganglia of origin from T1-T4, T5
2) any cervical paravertebral ganglion
3) the cardiac plexus
Postganglionic sympathetic efferent fibers may become incorporated in what neuronal structures after the paravertebral ganglion of origin in the pathway to the heart?
cardiac splanchnic nerves
What is the embryonic derivative of the adrenal gland?
- the adrenal cortex is derived from mesoderm
- the adrenal medulla is derived from neural ectoderm
What cell population of the adrenal medulla represents neural ectoderm?
chromaffin cells
Preganglionic sympathetic efferent fibers in the pathway to the adrenal gland will be incorporated in what neuronal structures?
- the sympathetic pathway to the paravertebral ganglion of origin
- then into lesser splanchnic
- least splanchnic
- lumbar splanchnic nerves
- finally in the adrenal nerve to the adrenal gland
Where will preganglionic sympathetic efferent fibers synapse in the adrenal gland pathway?
chromaffin cells of the adrenal medulla
Primary parasympathetic efferent neurons will be associated with which spinal nerves?
spinal nerves S2-S4
What is the location for a spinal nerve secondary parasympathetic efferent neuron?
typically an intramural ganglion or neural plexus
Which splanchnic nerves contain preganglionic parasympathetic efferent fibers?
nervi erigentes or pelvic splanchnic nerves
What is the location of the intramural parasympathetic ganglion?
on or in the wall of the target organ
Do spinal nerves typically contain postganglionic parasympathetic efferent fibers?
no
What is the name of the largest medullary feeder artery?
the artery of Adamkiewicz or the arteria radicalis magna anterior
What are the characteristics of the Artery of Adamkiewicz?
- it is predominantly found on the left side
- anterior medullary feeder
- located in the T9/T10 intervertebral foramen
- primary vascular supply to the lumbar enlargement
What will the intervertebral veins drain into?
the external vertebral venous plexus or Batson’s plexus
What is a unique histological feature of the veins of the vertebral column?
they appear to lack valves
What are the specific attachment sites for a cervical spinal nerve?
- sulcus for the ventral primary ramus on the costotransverse bar
- vertebral artery
What forms the lumbosacral tunnel?
- lumbosacral ligament
- transverse process of L5
- sacral ala
What condition is the result of encroahment on the L5 spinal nerve?
the far out syndrome
What ligament may contribute to the loss of size in the lumbar intervertebral foramen?
the transforaminal ligament
What is more likely the cause of nerve irritation at the sacral intervertebral foramen?
the tilt or position of the entire sacrum relative to the pelvis
What are some examples of destructive lesions of the vertebral body?
- tuberculosis
- hemangiomas
- osteoporosis
What may reduce the impact of intervertebral disc loss of integrity on the intervertebral foramen in the cervical and thoracic spine?
- the joint of Luschka in the cervicals
- the costocentral joint in the thoracics
What are examples of acquired alterations of the spinal curves identified in class?
- obesity
- pregnancy
- use of backpacks
What specific types of nerve fibers may be associated with spinal nerves?
- somatic efferent fibers
- preganglionic visceral, involuntary or autonomic efferent fibers
- postganglionic visceral, involuntary or autonomic efferent fibers
Identify the common ligaments of the vertebral column.
- anterior longitudinal ligament
- intervertebral disc
- posterior longitudinal ligament
- ligamentum flavum
- capsular ligament
- interspinous ligament
- ligamentum nuchae
- supraspinous ligament
- intertransverse ligament
What is the reason that nine common ligaments are identified but only eight will be attached at any specific vertebral couple?
the ligamentum nuchae and supraspinous ligaments attach to the spinous tubercles, but only one of these will be identified at a single vertebral couple
What is the cervical nucleus pulposus composed of?
fibrocartilage
What is the consequence of non-aggregated glycosaminoglycans in the lumbar nucleus pulposus?
the nucleus pulposus will loose water under deformation conditions
What cell is associated with the nucleus pulposus until about age eleven?
notochord cells
Which type of collagen is dominant in the nucleus pulposus?
collagen type II
What is unusual about the cervical annulus fibrosus?
it lacks any lamellar or layered organization
What is the organization of the lumbar annulus fibrosus?
it has 12-14 concentric cylindrical lamellae
Which type of collagen is dominant in the annulus fibrosus?
collagen type I
What is the organizational pattern for collagen fibers in the annulus fibrosus?
they are parallel with one another in a single lamellus and angled
What is the organization of collagen fibers between lamellae?
collagen fibers will be angle in the opposite direction such that a spiral - counterspiral organization is observed
What is the cartilage end plate derived from?
the epiphyseal plate
What is the principal type of collagen fiber within the cartilage end plate?
the type II collagen fiber
What is the direction of collagen fibers within the cartilage end plate?
collagen fibers are aligned anterior to posterior
What are the types of receptor endings in the intervertebral disc?
nociceptors and proprioceptors
What is the relationship between size of the intervertebral disc and receptor endings?
the larger the disc, the greater the variety of receptor endings
What are the sources of innervation of the intervertebral disc?
- sinu-vertebral nerve (sinus vertebral nerve, recurrent meningeal nerve)
- fibers from the ventral primary ramus
- fibers from the white ramus communicans
- fibers from the paradiscal ramus communicans
- fibers from the gray ramus communicans
What is the name given to the white ramus communicans which becomes embedded within the annulus fibrosus of the intervertebral disc?
the paradiscal ramus communicans
What neural plexus is formed, in part, by fibers from the paradiscal ramus communicans?
the lateral neural plexus of the vertebral column