Final Exam Flashcards
what does the the spinal cord run between
medulla oblongata to L1 or L2
what is the main function of the spinal cord
connects lower PNS with the brain
what pathways in the spinal cord are made of white matter
sensory/motor pathways up to and from the brain
what center in the spinal cord is made of gray matter
reflex center
what are the meningeal layers of the spinal cord
dura mater
arachnoid mater
pia mater
what is the epidural space of the spinal cord
fat-filled space around the dura mater
what is the subarachnoid space of the spinal cord
the space that contains CSF
what is the purpose of a lumbar puncture
to look at the CSF in subarachnoid space
what do bulges of the spinal cord indicate
regions where a larger number of neurons are entering/leaving the spinal cord
what does the myelinated (white matter) in the spinal cord create
columns
what does white matter in the spinal cord transport to the brain
sensory info
what does white matter in the spinal cord transport away from the brain
motor info
what are the ascending tracts of the spinal cord
exclusively sensory neuron axons
what are the descending tracts of the spinal cord
exclusively motor neuron axons
what are the commissural tracts of the spinal cord
interneurons that carry information from one side of the spinal cord to the other side
what are the three major columns on each side of the spinal cord
dorsal funiculus, lateral funiculus, ventral funiculus
what are the major columns on the sides of the spinal cord called
funiculi
what is grey matter of the spinal cord made of
neuronal cell bodies, dendrites, glia, nonmyelinated axons
what leaves the spinal cord at ventral horns
neurons associated with motor functions
where are visceral motor neurons (ANS) located
lateral horns of spinal cord
what regions of the spinal cord are lateral horns found in
thoracic and upper lumbar regions of the spinal cord
where do sensory neurons enter the spinal cord
dorsal horns
where are somatic sensory and visceral sensory cell bodies located in spinal cord
dorsal root ganglia
where are somatic motor cell bodies in spinal cord
ventral horns
where do axons of somatic motor neurons in the spinal cord exit
ventral root
where are visceral motor cell bodies located in the spinal cord
lateral horns
where do visceral motor neurons exit the spinal cord
through the ventral root
what do dorsal roots do
transport sensory info into spinal cord
what do ventral roots do
transport motor info away from spinal cord
what are spinal nerves made of
both ventral and dorsal roots
what is an example of an ascending sensory pathway
- sensory receptors activated
- sensory neurons synapse with interneurons within the dorsal horn of spinal cord gray matter
- interneurons transport signal via ascending tracts to thalamus
- ascending tracts to somatosensory cortex
what is decussation
axons from one side to the other
what is an example of a descending motor pathway
- primary motor cortex initiates a response
- interneurons transport signal to appropriate region of spinal cord
- interneurons synapse within ventral horns with motor neuron
- motor neuron transports signal to cells of action
what is the reflex arc
an automatic and rapid motor response
does the reflex arc require input from the brain
no
what are the two types of reflex arcs
monosynaptic
polysynaptic
what is a monosynaptic reflex
axon terminals of sensory neurons directly synapse on motor neuron within the spinal cord
how many neurons are involved in a monosynaptic reflex
two
how many synapses are involved in a monosynaptic reflex
one
are interneurons involved in monosynaptic reflexes
no
what is a polysynaptic reflex
axon terminals of sensory neurons connected via one or more interneurons to a motor neuron
how many neurons are involved in a polysynaptic reflex
3 or more
how many synapses are involved in a polysynaptic reflex
2 or more
are interneurons involved in a polysynaptic reflex
yes (creates multiple synapses)
what is the autonomic nervous system a part of
the peripheral nervous system
is the ANS under voluntary or involuntary control
involuntary
what three things does the ANS innervate
smooth muscle
cardiac muscle
glands
what is the ANS also called
visceral motor
how many neurons are involved in somatic motor
one motor neuron runs between the spinal cord and skeletal muscle
how many neurons are involved in the visceral motor (ANS)
two motor neurons run between spinal cord and target tissue
what are the two motor neurons involved in the ANS
preganglionic neuron
postganglionic neuron
within what do the preganglionic and postganglionic neurons synapse
within an autonomic ganglion
what are the general functions of the ANS
works in conjunction with the visceral sensory division
self-governing and involuntary motor responses
what are the two divisions of the ANS
parasympathetic
sympathetic
what are the characteristics of the parasympathetic division
rest and digest
conserves energy and oversees standard bodily functions
what are the characteristics of the sympathetic division
fight, fright, flight
mobilizes body in extreme situations
is the parasympathetic or sympathetic division a short term response that requires a lot of energy
sympathetic
does the parasympathetic or sympathetic division have more organs involved
sympathetic division
what is homeostasis
a balance between the two autonomic branches
where does the parasympathetic exit from
brainstem and sacral spinal nerves
where does the sympathetic exit from
thoracic and lumbar regions
in the parasympathetic pathway, which axon is long and which is short
preganglionic axon: long
postganglionic axon: short
in the parasympathetic pathway, where is the autonomic ganglion located
near or within target tissue
in the parasympathetic pathway, what is released within the autonomic ganglion
ACh
in the parasympathetic pathway, what is released between the postganglionic axon and the tissue
ACh
what is the vagus nerve
cranial nerve that contains 90% of the preganglionic parasympathetic fibers in the body
what is the purpose of the vagus nerve
to bring typical rest and digest activities in visceral muscle and glands
in the sympathetic pathway, which axon is short and which is long
preganglionic axon: short
postganglionic axon: long
where is the autonomic ganglion in the sympathetic pathway
near the spinal cord
in the sympathetic pathway, what is released within the autonomic ganglion
ACh
in the sympathetic pathway, what is released in between the postganglionic axon and tissue
norepinephrine
what is the sympathetic trunk ganglia
expansions of sympathetic trunk where pre and post ganglionic neurons synapse
what is the sympathetic trunk
a pathway for neurons of the sympathetic division
how does the sympathetic trunk run in relation to the spinal cord
parallel
where does the adrenal (suprarenal) gland sit
on top of both kidneys
what is the internal adrenal medulla a major organ of
the sympathetic nervous system
what is the adrenal gland
a specialized sympathetic ganglion that releases two excitatory hormones into the blood during fight or flight response
what are the two hormones that the adrenal gland releases
norepinephrine and epinephrine
how many pairs of cranial nerves are there
twelve
how many pairs of spinal nerves are there
31
how many cervical spinal nerves
8
how many thoracic spinal nerves
12
how many lumbar spinal nerves
5
how many sacral spinal nerves
5
how many coccygeal spinal nerves
1
what is a dermatome
a map showing the relationship between sensory receptors of the skin and the spinal nerves
what is paraplegia
loss of feeling/motor functions of legs
where is the damage in the spinal cord with paraplegia
between T1 and L2
what is quadriplegia
loss of feeling/motor functions of all 4 limbs
where is the damage of the spinal cord with quadriplegia
above T1
where is the damage if the diaphragm is impacted
above C4
what is shingles
a virus that resides in a single dorsal root ganglion from a previous chicken pox infection
with shingles, what happens if the immune system is weakened
the virus can multiply, travel along peripheral sensory nerves, and cause painful skin lesions
where are shingles lesions located
within a dermatome
what are two different types of sensory receptors in the PNS
simple: free nerve ending (dendrite or sensory neuron)
complex: specialized cell
what are the five classifications of receptors
mechanoreceptors
thermoreceptors
chemoreceptors
photoreceptors
nociceptors
what is echolocation
using echos to help with navigation without sight
what kind of pressure does a pacinian corpuscle respond to
deep pressure
what is a proprioceptor
encapsulated nerve endings that monitor stretch in locomotory organs (muscles, tendons)
what do proprioceptors give awareness of
movement
what does the cerebellum do with information from proprioceptors
uses the information to determine where our body parts are in space
what is the root hair plexus
free nerve ending wrapped around hair follicle
what does the root hair plexus respond to
movement of the hair
what are three different types of mechanoreceptors
pacinian corpuscle
proprioceptors
root hair plexus
what are thermoreceptors
free nerve endings that respond to temperature changes
where are thermoreceptors located
throughout the body
what are nociceptors
free nerve endings that respond to mechanical, thermal, or chemical stimuli
what is pain
the emotional way that our brain interprets stimulus from nociceptors
what are itch receptors
recently discovered free nerve endings
what do itch receptors respond to
inflammatory chemicals
what is the major difference between nociception and itch
pain elicits a withdraw reflex and itch elicits a scratch reflex
what do chemoreceptors respond to
certain chemicals
what has chemoreceptors that respond to chemicals of food
taste buds
what is the gustatory pathway
chemoreceptor of taste bud –> spinal cord –> thalamus –> gustatory cortex in insula
what do photoreceptors respond to
light
where are photoreceptors found
retina of the eye
what are the peripheral nerves
cranial nerves and spinal nerves
what do the spinal nerves split into
the dorsal ramus and the ventral ramus
what forms the nerve plexuses
the ventral rami
what is the exception to the rule that the ventral rami form the nerve plexuses
the thoracic region
- ventral rami innervate the thoracic cage
what does the dorsal ramus do
innervate muscles of the back
what is a nerve plexus
a network of nerves that supply specific regions of the body
what are the four nerve plexuses
cervical, brachial, lumbar, sacral
what is the cervical plexus formed from
ventral rami C1-C5
what does the cervical plexus innervate
back of the neck and diaphragm
what will happen with damage to the phrenic nerve
impaired breathing because the phrenic nerve stimulates the diaphragm
what is the brachial plexus formed from
ventral rami C5-T1
what does the brachial plexus innervate
upper limbs
what is the lumbar plexus formed from
ventral rami L1-L4
what does the lumbar plexus innervate
anterior region of the lower limbs
what is the sacral plexus formed from
ventral rami L4-S4
what does the sacral plexus innervate
posterior region of the lower limbs
what is the sciatic nerve formed from
the sacral plexus
what is polio
virus that can target motor neurons
what determines the level of paralysis in polio patients
which motor neurons are infected
what are iron lungs
machines that helped those whose respiratory muscles were paralyzed
what is postpolio syndrome
the lose of function of motor neurons after having polio
what causes postpolio syndrome
during infection with polio, motor neuron is destroyed but the neighboring neuron is not
-after recovery, the surviving neurons will extend axonal branches to muscles missing innervation and will then over-exert and lose function
what are the three special senses receptor types
chemoreceptors
mechanoreceptors
photoreceptors
what must be present to receive the information in order to detect a stimulus
a receptor
what are the two types of receptors
sensory nerve endings
specialized cells adjacent to sensory nerves
what does a stimulus generate
receptor potential
what does a receptor potential trigger
an action potential
what is a main difference between receptor potentials and action potentials
receptor potentials can be weak or strong
where does the action potential travel to
the brain to be “sensed”
what do mechanoreceptors detect
changes in pressure or movement
what do thermoreceptors detect
temperature change
what do nociceptors detect
pain
what do chemoreceptors detect
changes in chemical concentrations
what do photoreceptors detect
light energy
where are special senses localized and confined to
the head region
where are taste receptors found
taste buds in the mucosa of the mouth and pharynx
what are the three papillae that contain taste buds
circumvallate
fungiform
foliate
what papillae do not have taste buds
filiform
what do gustatory epithelial cells have
long microvilli called gustatory hairs that extend through taste pore
what do basal epithelial cells do
replace old and damaged cells
what do dissolved molecules in saliva enter
taste pore
what happens when molecules bind to receptors on gustatory hair cells
action potentials are generated, sensory neurons are stimulated, signals are sent to the CNS
what are the 5 taste types
sweet, sour, salty, bitter, umami
what is flavor
a combination of taste, smell, and texture
what is the gustatory pathway
taste receptors –> sensory nerve fibers in cranial nerves –> brainstem –> thalamus –> gustatory cortex (insula)
which special sense does not go through the thalamus
smell
where are olfactory receptors located
olfactory epithelium that covers superior nasal concha and superior nasal septum
what kind of neurons are olfactory sensory cells
bipolar neurons
what is the purpose of olfactory stem cells
continually form new olfactory sensory neurons
what does each bipolar olfactory neuron have
apical dendrite that is near the surface of the epithelium and olfactory cilia
where are chemoreceptors located
on olfactory cilia
what is the purpose of mucus
trap and dissolve molecules from inhaled air
what are the extensions of sensory neurons in the olfactory system
filaments of olfactory nerve
where do the filaments of olfactory nerve enter the CNS
through the cribriform plate of ethmoid bone
what do the filaments of the olfactory nerve synapse with in the olfactory bulb
mitral cells
what is the glomerulus
where the filaments of olfactory nerve synapse with mitral cells
where do the extensions from mitral cells relay olfactory information to via the olfactory tract
limbic system
primary olfactory cortex of the temporal lobe
what is anosmia
absence of smell
what are three causes of anosmia
blow to head/whiplash
colds/allergies
zinc deficiency
what are uncinate fits
olfactory hallucinations
what is the cause of uncinate fits
brain disorders
what is the dominant sense in humans
vision
what is the function of eyebrows
shade
prevent sweat from running into eyes