FINAL DRUGS

Question 1

Example of a Hydantoin

Answer 1

phenytoin (Dilantin)

Question 2

Example of a Iminostillbene drug

Answer 2

carbamazepine (Tegretol)

Question 3

Ending of Iminostillbenes

Answer 3

-azepine

Question 4

Anti-epileptic drug that causes bone marrow suppression, skin rash, liver toxicity, pancreatitis, and may be given with phenytoin or phenobarbital to increase levels of both meds.

Answer 4

Valproic Acid (Depakote)

Question 5

Anti-epileptic drug that causes stevens-johnsons skin rash, bone marrow suppression, auto induction and takes more than 2 months to start therapeutic effects.

Answer 5

carbamazepine (Tegretol)

Question 6

Anti-epileptic drug that can cause gingival hyperplasia, and must be diluted with normal saline in an IV and must be given slow.

Answer 6

phenytoin (Dilantin)

Question 7

Drugs not to give with hemorrhagic stroke. Must be given within 3 hours of CVA.

Answer 7

Thrombolytic drugs

Question 8

Anticholinesterase Drugs:

Answer 8

donepezil (Aricept)
rivastigmine (Exelon)
galantamine (Razadyne)

Question 9

Drugs that treat Alzheimers Disease

Answer 9

Anticholinesterase Drugs

NMDA Receptor Antagonists [memantine (Namenda)]

Question 10

Drugs that prevent cholinesterase (AChE) from breaking down acetylcholine (ACh) causing increased ACh.

Answer 10

Anticholinesterase Drugs

Question 11

Drugs that inhibit the activity at NMDA receptors to slow disease process and decrease or stop cognitive degeneration.

Answer 11

NMDA Receptor Antagonists

Question 12

Drugs that inhibit actions of MAO-B enzymes that break down dopamine resulting in increased dopamine.

Answer 12

Selective MAOI Therapy/ MAO-B Inhibitors

Question 13

Drugs that cause the release of dopamine from storage in basal ganglia

Answer 13

Dopamine Modulators

Question 14

Drugs that stimulates dopamine receptors to = the same effect as if dopamine had been bound.

Answer 14

Dopamine Receptor Agonists

Question 15

The precursor of dopamine that crosses the blood brain barrier before it is broken down into dopamine which increases dopamine in the CNS

Answer 15

Levodopa

Question 16

drugs that inhibit COMT enzymes from breaking down dopamine

Answer 16

COMT Inhibitors

Question 17

Drugs that block the effect of Each at cholinergic receptors

Answer 17

Anticholinergics

Question 18

Example of a NMDA Receptor Antagonists

Answer 18

memantine (Namenda)

Question 19

Example of Selective MAOI Therapy drugs/ MAO-B Inhibitors

Answer 19

selegiline (Eldeprly)

rasagiline (Azilect)

Question 20

Dopamine Modulators

Answer 20

amantadine (Symmetrel)

Question 21

Dopamine Receptor Agonists

Answer 21

pramipexole (Mirapex)

ropinirole (Requip)

Question 22

Used to treat Parkinson’s Disease int he early stages

Answer 22

amantadine (Symmetrel)

Question 23

Drug used to treat Restless Leg Syndrome. Drugs to use alone when treating Parkinsons before need to Levodopa or adjunct w/Levodopa.

Answer 23

Dopamine Receptor Agonists: Mirapex + Requip

Question 24

1 Therapy for Parkinsons Disease

Answer 24

Levodopa

Question 25

Adjunct with levodopa when on/off phenomenon occurs.

Answer 25

COMT Inhibitors : Comatan + Tasmar

Question 26

Contraindications of COMT Inhibitors: Comatan + Tasmar

Answer 26

Liver Dysfunction | Alcoholism

Question 27

Contraindication of Anticholinergics : Cogentin

Answer 27

Glaucoma Kidney Failure Constipation

Question 28

Adverse effects of Anticholinesterase drugs

Answer 28

``` Bradycardia hypotension fainting pupillary constriction Bronchial Constriction Cholinergic Crisis SLUD ```

Question 29

Adverse effects of Selective MAOI Therapy/MAO-B Inhibitors

Answer 29

Hypertensive crisis after consuming tyramine containing foods

Question 30

Adverse effects of Dopamine Modulators

Answer 30

Dizziness Insomnia Nausea

Question 31

Adverse effects of Dopamine Receptor Agonists

Answer 31

Orthostatic/Postural hypotension Dark urine/sweat paranoia, hallucinations dyskinesia/spasticity

Question 32

Adverse effects of COMT Inhibitors

Answer 32

Nausea/Vomiting Dark Urine Liver Failure Dyskinesia/Spasticity

Question 33

adverse effects of anticholinergics

Answer 33

``` Tachycardia hypertension pupillary dilation bronchial dilation urinary retention dry mouth constipation hyperthermia blurred vision Cant SSSS ```

Question 34

Drug interaction of Dopamine Receptor Agonists

Answer 34

Protein | Vit B6

Question 35

Drug interactions of Selective MAOI Therapy drugs/ MAO-B Inhibitors

Answer 35

Tyramine

Question 36

Drug interactions of Dopamine Receptor Agonists

Answer 36

CNS Depressants (alcohol + opioids)

Question 37

Antidote to Anticholinesterase drugs

Answer 37

Atropine

Question 38

drug of choice for young parkinson's patients. first or second line therapy for elderly patients.

Answer 38

Dopamine Receptor Agonists (Mirapex + Requip)

Question 39

this drug can be used as an adjunct to levodopa for "off periods". Can be used to reduce dyskinesia associated with later stages of Parkinson's Disease

Answer 39

Dopamine Receptor Agonists (Mirapex + Requip)

Question 40

Levodopa is no longer effective after how long?

Answer 40

5-10 years of use

Question 41

drug that prevents the breakdown of levodopa in the PNS to decrease adverse effects

Answer 41

carbidopa-levodopa (Sinemet)