Brainscape's Knowledge GenomeTM

Browse over 1 million classes created by top students, professors, publishers, and experts.


See full index

Pharmacology (Spring 2019) > Final - Contraindications > Flashcards

Final - Contraindications Flashcards

1
Q

methylergonovine

A

Severe HTN = preeclampsia is not a candidate

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
2
Q 
Antacids
Antifungals
Alcohol
Seizure  meds
food
A

isoniazide

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
3
Q

History of hearing loss

When administered with metformin, may increase risk of lactic acidosis

A

vancomycin

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
4
Q

Pregnancy
CNS disorders
Renal impairment
Increase anticoagulant effects with warfarin
Milk
Slow metabolism xanthines (caffeinated = hyperactive reaction

A

ciprofloxacin

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
5
Q

warfarin + fluconazole =

A

increase bleeding

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
6
Q 
Hepatic impairment
Hypokalemia
Pregnancy = fetal malformations
Warfarin = increases bleeding
Oral hypoglycemic
Erythromycin – increase risk of cardiotoxicity & death
A

fluconazole

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
7
Q 
Suppressive immune system (anemic)
Hepatic impairment (increase ALT, AST, chronic alcoholic)
Warfarin
Disulfiram
Lithium
A

metronidazole

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
8
Q

Cardiac Disease = can prolong PR interval = 3rd degree heart block = fatal
Hepatic impairment
Statins = increase risk for myopathy
Antidysrhythmic durgs = life-threatening dysrhythmias

A

lopinavir with ritonavir

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
9
Q

Warfarin
Pregnancy/lactation
Oral contraceptives
Black cohosh (herbal supp.)

A

tomoxifen

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
10
Q 
STATINS = myopathy, muscle breakdown, rhabdomyelosis
Hepatotoxic drugs
SUN
Pregnancy
**Grapefruit juice
alcohol
A

cyclosporine

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
11
Q

Hypersensitivity

Lactation = caution with pregnancy & decrease bone marrow reserve

A

methimazole

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
12
Q

2nd, 3rd Degree AV block
Lupus
Myasthenia gravis
Bone marrow depression

A

procainamide

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
13
Q 
Severe bradycardia
Cardiogenic shock
Sick sinus syndrome: SA node not functioning properly
Severe sinus node dysfunction
3rd degree AV block
COPD
Multiple drug reactions! =
A

amniodarone

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
14
Q

Cardiogenic Shock
2nd, 3rd Heart block
Interact with some other meds

A

propranolol

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
15
Q
  • bradycardia

- AB block

A

esmolol

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
16
Q 
AV block
Sick sinus syndrome
Sever hypotension
Bleeding aneurysm
Intracranial surgery
A

verapamil

17
Q 
Internal bleeding
Intracranial bleeding
Severe HTN (bc of burst blood vessel)
Bacterial endocarditis (inflammation around heart)
Meds & herbal supplements
A

heparin

18
Q
  • IV Dextran

- oral anticoagulants

A

abciximab

19
Q

Antagonizes thrombolytics
Estrogens & oral contraceptics: hypercoagulation
Recent thromboembolic disease (DIC)
Renal impairment
Urinary tract bleeding: promotes formation of clots in renal pelvis or ureters) =

A

aminocaproic acid

20
Q

Intracranial hemorrhage

WARFARIN c INR >1.7 or PT >15

A

alteplase

21
Q

lithium + furosemid =

A

toxicity

22
Q

can you have anuria with diuretics

A

no

23
Q

Phsphodiesterase-5 inhibitors (Viagra)
Anything that causes hypotension
Worsened by increase vasodilation (bleeding, ICP)
Pericardial tamponade & constrictive pericarditis
Liver & renal disease
Treat before: dehydration or hypovolemia

A

nitroglycerine

24
Q

High intracranial pressure (brings fluid with it and increase pressure)
Renal failure
Sympathomimetics will block action of it

A

nitroprusidde sodium

25
Q

Seizure disorder
Pregnancy (it has causes of birth defects)
Cardiac disease/MI
Other CNS depressants = increased sedation
Hyperthyroifism/Thyroid hormone = dysrhythmias
MAOIs
SSRIs = imipramine toxicity
St. John’s Wort = risk of serotonin syndrome
Herbal supplements
Increased ICP
Hepatic disase

A

tricyclics

26
Q

Grapefruit juice
Bipolar disorder (stimulates their manic phase)
Newborn may have withdrawal symptoms
Diabetes
Phenothiazine
Other CNS depressants = increased sedation
St. John’s Wort = risk of serotonin syndrome
Antidysrhythmics & benzos
Warfarin, asa, NSAIDS (may increase bleeding risk)

A

SSRIs

27
Q 
Mania
Seizure
HTN
Hepatic disease
Elderly, children, lactating women
A

duloxetine

28
Q

NSAIDS & thiazides + lithium =

A

increased lithium reabsorption = potential toxicity

29
Q

haloperidol + lithium =

A

increase neurotoxicity

30
Q

CNS depression, seizures, dysrhythmias, hypotension, suicidal ideation
DKA
lactation
SSRIs: increase levels of risperidone
CNS depressants: CNS depression
Antihypertensive: may potentiate hypotension

A

risperidone

31
Q 
Lactation 
Seizure disorders
Drugs metabolized by liver
SSRIs
Antipsychotics & lithium increase risk of EPS
Grapefruit
A

aripiprazole

32
Q

paralytic ileus

A

hydromorphone

33
Q

DO NOT USE WITHIN 14 DAYS OF MAOI (hypersensitivity)

not recommended for use longer than 48 hrs, chronic pain, or PCA

A

meperidine

34
Q

Grapefruit juice
Kava
Pregnancy & lactation
Narrow-angle glaucoma

A

benzodiazepines

35
Q

Soybean & egg products
OB pt’s
Increased ICP (due to increased CO2)

A

propofol

Pharmacology (Spring 2019) (8 decks)

Brainscape helps you reach your goals faster, through stronger study habits.
© 2025 Bold Learning Solutions. Terms and Conditions