FINAL-Blood Coagulation

Question 1

Transfusion ratio (PRBC to FFP)

Answer 1

1:1 or 1:2

Question 2

Effects of bank blood-potentially harmful

Answer 2

Increased potassium
Hemolysis

Question 3

How much does Hgb change with each unit of blood given

Answer 3

1 unit PRBC = Hgb increase by 1 g/dL

Question 4

X-Linked recessive blood disorder. Undergoing surgery. What can you give them?

Answer 4

Factor VIII
Factor VII
Desmopressin

Question 5

Universal FFP donor

Answer 5

AB+

Question 6

Patient in the ICU in DIC. What administer before surgery?

Answer 6

FFP
Platelets
Cryo

Question 7

vWF disease treatment

Answer 7

Type 1: Desmopressin
Type 2: vWF concentrate
Type 3: vWF concentrate

Tranexamic acid = adjunctive therapy

Cryo = can be used

Question 8

Blood vessel injured. What happens at vessel, what’s being released?

Answer 8

TF
Thromboxane A2, ADP, Serotonin (vasoconstrictors)

Question 9

2 things that can happen post transfusion. Leading cause of death?

Answer 9

TRALI (Onset within 6 hrs following transfusion)

TACO (Onset 6-12 hours after transfusion- LEADING CAUSE OF TRANSFUSION RELATED DEATH)

Question 10

TRALI treatment

Answer 10

Supportive/use lung protective strategies
-Maximize PEEP
-Low tidal volume
-Avoid over hydration

-No left atrial hypertension or volume overload (TACO)