Fetal Development Exam 7 Flashcards
Initial Fertilized Egg
Zygote
contains all genetic information for all of life
zygote
- Corona Radiata
- Zona Pellucida
- Plasma membrane of secondary oocyte
- Cytoplasm of secondary oocyte
Path of sperm cell
FIrst 36 hours
From 1 to 2 cells
36-72 hours
From 2 - 16 cells
16 cells
- solid
- where differentiation begins
Morula
Days 4-5
100 cells
100 cells =
blastocyst
- Now in uterus
- Fluid-filled hollow sphere
- differentiation has begun
Blastocyst
Thin, spherical shells, that forms placenta
Trophoblasts
Cells become embryonic disc –> embryo
inner cell mass
6 days after ovulation
- Implantation begins
- Trophoblast cells do work
6 days after ovulation,
Implantation…?
takes one week; done by 14th day
6 days after ovulation,
What are trophoblasts doing?
those next to inner mass cells adhere to endometrium
-form placenta
Secrete HCG
-Form chorion after implanation
Trophoblasts secrete HCG, what does it do?
Stimulates corpus luteum to continue producing progesterone and estrogen
-An LH-like hormone
Stimulates corpus luteum to continue producing progesterone & estrogen
Human Chorionic Gonadotropin
First produced by trophoblast cells of blastocyst
Detectable in blood by 3rd week of gestation (1 week after fertilization)
Production continued by chorion
Human Chorionic Gonadotropin
Peaks at end of 2nd month
Then falls to low at end of 4th month
Remains stable thereafter
Human Chorionic Gonadotropin
Who provides nutrients?
first?
Large ovum provides nutrients until implanation
Who provides nutrients?
2nd
Digestion of endometrial cells by trophoblasts
Who provides nutrients?
3rd
Placenta provides (by 2nd month)
8 weeks
Humanoid
Groundwork of all systems is laid
1 inch long
Has limbs, fingers, and toes
Major organs present
8 weeks
Humanoid
14 – 16 inches
Fine hair and fingernails
Has everything but hypothalamus and lungs
28 weeks
By end of 8th week,
- All of the organ systems have been started (even if they may be quite primitive)
- The placenta is now producing ___, ___, and other hormones and is truly an endocrine organ
estrogen, progesterone
By end of 8th week,
- The corpus luteum quits functioning as a hormone producer
- The gonads of the male fetus now begin to produce ___
testosterone
These tissues sensitive to tesosterone
Reproductive System
Brain
- Gonads form at about 8 weeks
- Male external genitalia form in the presence of testosterone
- Female external genitalia form in the absence of testosterone
Testosterone influences on Genitalia
Testosterone on
- Corpus Callosum?
- Brain
CC: smaller > Women, fewer neural pathways
Brain: may affect neural organization
The interstitial nucleus of the anterior hypothalamus is larger/smaller in the male than in the female
larger
The right cortex of the cerebrum of the brain is thicker?/thinner? than the cortex of the left side of the brain when testosterone has been present during fetal development
Thicker
The left side of the brain controls the right side of the body
The right side of the brain controls the left side of the body
Voluntary Motor Skills
SYmmetric brain
The left side of the brain senses the right side of the body
The right side of the brain senses the left side of the body
Cutaneous Sensation
Symmetric Brain
Language
Mathematics
Logic
Left Side Dominant
Ability to put ideas into words & say them
Right-handedness
Left Side Dominant
Controls the ability to put ideas into words and say them
Is on the left side of the brain in most (?~97%) of people
Broca’s Area of Brain
Musical ability
The recognition of complex visual patterns
The expression of emotions
Right Side of Brain
Facial Recognition
“Ah-ha” (insightful) nature
Fantasy & Spontaneity
Right Side
Who is better at
- On tests of perceptual speed
- In their ability to remember things that are out of place
- With ideational and verbal fluency
- In tasks requiring fine-motor skills
- On mathematical calculation tests
Women
Who is better at:
- At doing mental manipulation of 3-dimensional objects
- In their accuracy at target-directed motor skills
- At analyzing complex visual patterns
- With mathematical reasoning or logic
men
A condition resulting when the adrenal gland grows out of control to a size that is inappropriately large
Congenital Adrenal Hyperplasia
In this situation the adrenal gland secretes inappropriately large amounts of hormones (including androgens, male hormones) prior to birth
Congenital Adrenal Hyperplasia
Their fetal development is significantly influenced by the androgen (testosterone) hormone
The results are similar to that of the normal male
females with CAH
Treatment of the abnormal adrenal gland soon after birth
- Can correct the masculinization of the genitals
- But the prenatal effects of the androgens on the brain can not be reversed
females with CAH
tend to be more verbal than males
females