Fetal circulation Flashcards

1
Q

Why is pulmonary blood flow minimal in fetuses?

A

There is no need for any significant pulmonary circulation since the placenta is the fetal organ of gas exchange

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2
Q

Where does blood flow to the placenta come from?

A

Umbilical arteries (branch of anterior iliac arteries)

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3
Q

Blood returns to the fetus from the placenta via what vessels?

A

Umbilical vein

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4
Q

What are the 3 fetal shunts?

A

Ductus arteriosis
Foramen ovale
Ductus venosus

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5
Q

What is the route of blood through the ductus arteriosis?

A

Superior vena cava–right atrium–right ventricle–pulmonic trunk–ductus arteriosus–aorta

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6
Q

What is the route of blood through the foramen ovale?

A

Inferior vena cava–right atrium–forament ovale–left atrium–left ventricle–aorta

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7
Q

What is the route of blood through the ductus venosus?

A

Umbilical vein–ductus arteriosus—inferior vena cava

Portal vein–ductus arteriosus–inferior vena cava

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8
Q

Ductus arteriosus and foramen ovale allow blood to bypass what?

A

Lungs

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9
Q

The ductus venosus allow umbilical and portal blood to bypass what?

A

Liver

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10
Q

Where is the greatest oxygen saturation in fetal blood?

A

Umbilical vein-80% (from placenta)

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11
Q

What are 3 circulatory readjustments at birth?

A
  1. Increased blood flow through lungs and liver
  2. Loss of blood flow through the placenta
  3. Closure of foramen ovale, ductus arteriosis, and ductus venosus
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12
Q

What occurs when there is increased blood flow though lungs and liver–a circulatory readjustment at birth?

A

Pulmonary and vascular resistance decreases

-Decreased RVP, pulmonary arterial BP

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13
Q

What occurs when there is a loss of blood flow through the placenta–a circulatory readjustment at birth?

A

Doubles the systemic vascular resistance

-Increased LAP, LVP, aortic BP

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14
Q

What occurs with the closure of foramen ovale?

A

Due to reversal of pressure gradient between RA and LA, flap closes

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15
Q

What occurs with the closure of ductus arteriosis?

A

Reversal of flow from aorta to pulmonary artery, and increased oxygen levels cause constriction of smooth muscle

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16
Q

What occurs with the closure of ductus venosus?

A

Cause unknown

Allows portal blood to perfuse liver sinuses

17
Q

In the fetus, are the right and left ventricle pump in parallel or series into the aorta?

A

Parallel

18
Q

In the fetus, how many right to left shunts are there to bypass the lungs?

A

2

19
Q

Foramen ovale shunts most of the blood returning to the heart from where?

A

Inferior vena cava

20
Q

Ductus arteriosus shunts most blood returning to the heart from where?

A

Superior vena cava