FENTANYL Flashcards
Indications
Adjunct to anesthesia
Post operative pain
Class
Synthetic opioid analgesic (intermediate - acting)
Mechanism of Action
Acts on mu and kappa opioid receptors
Potency
100 times more potent than morphine
IV Sedation Dose
Sedation Dose: 0.5 - 1 ug / kg IV
Onset
IV Immediate
Peak Effect
5-6 min
Duration
IV 30-60 min
Elimination Half Life
3-6 hrs
Elimination
Hepatic
Accumulates in larger, prolonged doses
CNS Effects
Potent analgesic
Some sedative
NO AMNESTIC
Potentiated by sedatives, volatile anesthetics, NO
CVS Effects
Hypotension
Bradycardia
Respiratory Effects
Respiratory Depression
GI Effects
Nausea, Vomiting, Biliary Tract Spasm, Constipation
MSK Effect
Muscle rigidity