Female Urinary Incontinence Flashcards
What are the 2 parts of the urinary tract?
- Upper urinary tract
- Ureters and kidneys
- Low pressure distensible conduit with intrinsic peristalsis
- Transports urine from nephrons via ureters to bladder
- Lower urinary tract
- Bladder and urethra
- Bladder fills at rate of 0.5-5mls/min
- Low pressure storage of urine
What is the upper urinary tract composed of?
- Ureters and kidneys
What is the lower urinary tract composed of?
- Bladder and urethra
The bladder fills at what rate?
- Bladder fills at rate of 0.5-5mls/min
What nerves supply the bladder?
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How does the bladder accomodate increasing volume at constantly low pressure?
- Accommodates increasing volume at constantly low pressure by inhibition of contractions by giving gradual awareness to filling
- Cortical activity to allow this, activates reciprocal guarding reflex by Rhabdosphincter contraction, increasing sphincter contraction and resistance
- Activates sympathetic pathway and reciprocal inhibition of parasympathetic pathway, mediates contraction at bladder base and proximal urethra
How is bladder emptying achieved?
- Requires detrusor contraction, urethral relaxation, sphincter co-ordination, absence of obstruction or shunts
- Cortical activity
- Pontine micturition centre
- Activation of parasympathetic pathway and inhibition of sympathetic pathway
What is urinary incontinence (UI)?
Any involuntary leakage of urine
What is stress urinary incontinence (SUI)?
- Involuntary leakage on effort or exertion, on sneezing or coughing
What is urge urinary incontinence (UUI)?
- Involuntary leakage accompanied by or immediately preceded by urgency
What is mixed urinary incontinence (MUI)?
- Involuntary leakage accompanied by or immediately preceded by urgency and on effort or exertion, or on coughing or sneezing
What are the different kinds of urinary incontinence?
- Urinary incontinence (UI)
- Any involuntary leakage of urine
- Stress urinary incontinence (SUI)
- Involuntary leakage on effort or exertion, on sneezing or coughing
- Urge urinary incontinence (UUI)
- Involuntary leakage accompanied by or immediately preceded by urgency
- Mixed urinary incontinence (MUI)
- Involuntary leakage accompanied by or immediately preceded by urgency and on effort or exertion, or on coughing or sneezing
What is the aetiology of female urinary incontinence?
- Anatomical defect in the anterior vaginal wall and pubo-urethral ligament
What is the prevalence of female urinary incontinence?
- 10-25% of woman age 15-60
- 15-40% of woman over 60
- Prevalence increases with age
What are risk factors for female urinary incontinence?
- Age
- Parity
- Menopause
- Smoking
- Medical problems
- Increased abdominal pressure
- Pelvic floor trauma
- Denervation
- Connective tissue disease
- Surgery
What is the presentation of female urinary incontinence?
- Irritation symptoms
- Urgency (sudden compelling desire to void)
- Increased daytime frequency (>7)
- Nocturia (>1)
- Dysuria
- Naematuria
- Incontinence symptoms
- Stress UI
- Urgency UI
- Coital incontinence (during sexual intercourse)
- Voiding symptoms
- Straining to void
- Interrupted flow
- Recurrent UTI
- Prolpase symptoms
- Vaginal lump, dragging sensation in vagina
- Bowel symptoms
- Anal incompetence
- Constipation
- Faecal evacuations
- Dysfunction
- IBS
What is the medical term for incontinence during sex?
Coital incontinence
What investigations should be done for urinary incontinence?
- 3 day urinary diary
- Looks at fluid intake (quantity and quality), urine out-put, daytime frequency, nocturia, average voided volume
- Urinalysis
- Post voiding residual volume assessment (usually by bladder scanning)
- Urodynamics
- Only if indicated if surgical treatment is contemplated
What does a urinary diary record?
- Looks at fluid intake (quantity and quality), urine out-put, daytime frequency, nocturia, average voided volume
What is the management of female urinary incontinence?
- Stress urinary incontinence occurs when intra-abdominal pressure exceeds urethral pressure, causing leakage. So management is aimed at increasing urethral closure pressure
- Lifestyle changes
- Stop smoking, lose weight, healthy food, stop drinking alcohol and caffeine
- Indications – everyone unless they do not wish it or previously failed
- Physiotherapy
- Pelvic floor muscle training
- Effect – reinforcement of cortical awareness of muscle groups, hypertrophy of existing muscle fibres, general increase in muscle strength and tone
- Pelvic floor muscle training
- Pharmacological
- Duloxetine
- Indication – moderate to severe stress urinary incontinence, does not wish for surgery or previous failed surgery, patients family is not complete
- Duloxetine
- Surgical
- Colposuspension
- Urethral/bladder neck closure
- Suburethral sling
- Tension free vaginal tape (TVT)
- Advantages – less operative and postoperative morbidity than colposuspension
- Complications – bladder perforation, vaginal and urethral erosion, vascular injuries
What lifestyle changes can help with female urinary incontinence?
- Stop smoking, lose weight, healthy food, stop drinking alcohol and caffeine
What is the effect of pelvic floor muscle training?
- Effect – reinforcement of cortical awareness of muscle groups, hypertrophy of existing muscle fibres, general increase in muscle strength and tone
What drug can be used for female incontinence?
- Duloxetine
- Indication – moderate to severe stress urinary incontinence, does not wish for surgery or previous failed surgery, patients family is not complete
What surgery can be done for female incontinence?
- Colposuspension
- Urethral/bladder neck closure
- Suburethral sling
- Tension free vaginal tape (TVT)
- Advantages – less operative and postoperative morbidity than colposuspension
- Complications – bladder perforation, vaginal and urethral erosion, vascular injuries
What are possible complications of female urinary incontinence?
- Reduced quality of life
- Reduce social relationships and activities
- Mental health
- Impair emotional and psychological well-being, sexual relationships, embarrassment
What is overactive bladder syndrome?
A symptom complex usually, but not always, related to urodynamically demonstrable detrusor overactivity
Describe the epidemiology of overactive bladder syndrome (age, sex)?
- Prevalence increases with age, woman affected more than men until age exceeds 65 then men are affected more than woman
What are risk factors for urge incontinence?
- Advanced age
- Diabetes
- Urinary tract infections
- Smoking
What are the defining symptoms of overactive bladder syndrome?
- Urgency (with/without urgency incontinence), usually with frequency and nocturia
- Definitions of symptoms
- Urgency – complaint of sudden, compelling desire to pass urine
- Urge incontinence – complaint of involuntary leakage of urine accompanied or immediately preceded by urgency
- Frequency – voids to often
- Nocturia – wake during the night to void
What is urgency?
- Urgency – complaint of sudden, compelling desire to pass urine
What is urge incontinence?
- Urge incontinence – complaint of involuntary leakage of urine accompanied or immediately preceded by urgency
What is frequency?
- Frequency – voids to often
What is nocturia?
- Nocturia – wake during the night to void
What is the management for overactive bladder syndrome?
- Life style interventions
- Normalise fluid intake, reduce caffeine, fizzy drinks, chocolate, stop smoking, weight loss
- Bladder training programme
- Timed voiding with gradually increasing intervals
- Pharmacological
- Antimuscarinic, could be
- Solifenacin (Vesicare 5-10mg )
- Fesoteridine (Toviaz 4-8 mg)
- Trospium Chloride (60mg XL)
- Darifencain (Emselex 7.5-15 mg ) – Constipation; FI
- Lyrinel XL (10-20 mg )
- Oxybutinin (5-10 mg/ tds)
- Kentera Patches
- Tri-cyclic antidepressants
- Imipramine
- Antimuscarinic, could be
- Recent advances on treatment
- Botox
- Neuromodulation
- Needle stimulation
- Effect – reflex inhibition to the detrusor muscle