Complications in Pregnancy 1 Flashcards

1
Q

What are some examples of complications in pregnancy?

A
  • Miscarriage
  • Ectopic pregnancy
  • Antepartum haemorrhage
  • Preterm labour
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2
Q

What is a miscarriage?

A

Miscarriage = spontaneous loss of pregnancy before 24 weeks gestation

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3
Q

What is an abortion?

A

Abortion = voluntary termination

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4
Q

What are the different classes of miscarriage and there presentation?

A
  • Threatened
    • Bleeding from gravid uterus before 24 weeks gestation where there is viable foetus and no evidence of cervical dilation
    • Vaginal bleeding with or without pain, viable pregnancy, closed cervix on speculum examination
  • Inevitable
    • Becomes inevitable if cervix has already began to dilate
    • Viable pregnancy, open cervix with bleeds that could become heavy
  • Incomplete
    • Only partial expulsion of products of conception
    • Vaginal bleeding, open cervix
  • Complete
    • Expulsion of all products of conception
    • Cervix closed and bleeding has stopped
  • Septic
    • After incomplete miscarriage risk of ascending infection, known as septic abortion
  • Missed
    • Foetus has died but uterus made no attempt to expel the products of conception
    • No symptoms, or could have bleeding
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5
Q

What is a threatened miscarriage?

A
  • Bleeding from gravid uterus before 24 weeks gestation where there is viable foetus and no evidence of cervical dilation
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6
Q

What is an inevitable miscarriage?

A
  • Becomes inevitable if cervix has already began to dilate
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7
Q

What is an incomplete miscarriage?

A
  • Only partial expulsion of products of conception
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8
Q

What is a complete miscarriage?

A
  • Expulsion of all products of conception
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9
Q

What is a septic miscarriage?

A
  • After incomplete miscarriage risk of ascending infection, known as septic abortion
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10
Q

What is a missed miscarriage?

A
  • Foetus has died but uterus made no attempt to expel the products of conception
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11
Q

What is the aetiology of miscarriage?

A
  • Abnormal conceptus
    • Chromosomal, genetic, structural
  • Uterine abnormality
    • Congenital, fibroids
  • Cervical weakness
    • Primary, secondary
  • Maternal
    • Increasing age, diabetes
  • Idiopathic
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12
Q

What is the prevalence of miscarriage?

A

15% in lifetime

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13
Q

What is the management of miscarriage?

A
  • Threatened
    • Conservative, just wait
  • Inevitable
    • If bleeding heavy may need evacuation
  • Missed
    • Conservative
    • Medical – prostaglandins (misoprostol)
    • Surgical – SMM (surgical management of miscarriage)
  • Septic
    • Antibiotics and evacuate uterus
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14
Q

What is an ectopic pregnancy?

A

Pregnancy implanted outside uterine cavity, usually in ampulla of fallopian tubes

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15
Q

Where does an ectopic pregnancy usually occur?

A

Ampulla of fallopian tubes

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16
Q

What is the incidence of ectopic pregnancy?

A

1:90 pregnancies

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17
Q

What are risk factors for ectopic pregnancy?

A
  • Pelvic inflammatory disease
  • Previous tubal surgery
  • Previous ectopic
  • Assisted conception
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18
Q

What is the presentation of ectopic pregnancy?

A
  • Period of ammenorhoea (with positive urine pregnancy test)
  • Maybe vaginal bleeding
  • Maybe abdominal pain
  • Maybe GI or urinary symptoms
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19
Q

What investigations are done for ectopic pregnancy?

A
  • USS
    • No intrauterine gestational sac, may see adnexal mass, fluid in pouch of douglas
  • Serum BHCG levels
    • May need to track over 48 hour intervals
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20
Q

What is the mangement of ectopic pregnancy?

A
  • Medical
    • Methotrexate
  • Surgical
    • Laparoscopy
    • Or maybe salopingectomy (remove the tube) or salpingotomy (leave a damaged tube, remove embryo)
  • Conservative
21
Q

What does APH stand for?

A

Antepartum haemorrhage

22
Q

What is an antepartum haemorrhage?

A

Haemorrhage from the genital tract after 24th week of pregnancy but before delivery of baby

23
Q

What is the aetiology of APH?

A
  • Placenta praevia
    • Placenta partially or totally covers the mothers cervix
  • Placental abruption
  • Local lesions of genital tract
  • Vasa praevia
    • Foetal blood vessels cross or run near the internal opening of uterus
  • Idiopathic
24
Q

What is a placenta praevia?

A

Placenta partially or completely covers mothers cervix

25
What are the different classes of placenta praevia (old classification system)?
* Grade 1 * Placenta encroaching on the lower segment but not he internal cervix os * Grade 2 * Placenta reaches internal os (orifice of cervix) * Grade 3 * Placenta eccentrically covers the os * Grade 4 * Central placental praevia
26
What are the different classes of placenta praevia, new system?
* Low lying placenta * Less than 20mm from internal OS * Placental previa * Covering os
27
What is the incidence of placenta praevia?
1/200 pregnancies
28
What are the risk factors for placental praevia?
* Multiparous woman * Multiple pregnancies * Previous caesarean section
29
What is the presentation of placenta praevia?
* **Painless PV bleeding** * Malpresentation of foetus * Incidental
30
What investigations are done for placental praevia?
* USS * **Vaginal examination must not be done with suspected placental praevia**
31
What should NEVER be done in suspected case of placental praevia?
Vaginal examination
32
Describe the management of placental praevia?
* Depends on * Gestation * Severity * Caesarean section * Medical management * Oxytocin, ergometrine, carboprost, tranexamic acid * Surgical management * Balloon tamponade * B lynch cutre, ligation of uterine, iliac vessels, hysterectomy
33
What is a possible complication of placental praevia?
* Post-partum haemorrhage
34
What is a placental abruption?
Haemorrhage resulting from premature separation of placenta before the birth of the baby
35
What is the prevalence of placental abruption?
0.6% of pregnancies
36
What are risk factors for placental abruption?
* Pre-eclampsia/chronic hypertension * Multiple pregnancy * Polyhydramnios * Smoking, increasing age, parity * Previous abruption * Cocaine use
37
What are the different clinical categories of placental abruption?
* Revealed (see the blood) * Concealed (bleeding but inside so cannot see) * Mixed (concealed and revealed)
38
What is the presentation of placental abruption?
* **Pain** * Vaginal bleeding * Increased uterine activity
39
What is the mangement of placental abruption?
* Varies from expectant treatment, attempting delivery or caesarean section depending on * Amount of bleeding * General condition of mother and baby * Gestation
40
What are possible complications of placental abruption?
* Maternal shock, collapse * Foetal distress then death * Maternal DIC (disseminated intravascular coagulation), renal failure * Postpartum haemorrhage
41
What is preterm labour?
Onset of labour before 37 weeks completed gestation (259 days)
42
What are the different categories of preterm labour?
* Mildly preterm * 32-36 weeks * Very preterm * 28-32 weeks * Extremely preterm * 24-28 weeks
43
When is labour considered to be preterm?
Before 37 weeks completed gestation (259 days)
44
Describe the epidemiology of preterm labour (incidence)?
* 5-7% in single pregnancy * 30-40% in multiple pregnancy
45
What are risk factors for preterm labour?
* Idiopathic (most common) * Multiple pregnancy * Polyhydramnios * APH * Pre-eclampsia * Infection such as UTI * Prelabour premature rupture of membranes
46
How is preterm labour diagnosed?
* Contractions with evidence of cervical change on VE * Foetal fibronectin test
47
Describe the management of preterm labour?
* \<24-26 weeks * Poor prognosis * All cases considered viable * Consider tocolysis to allow steroids/transfer * These are drugs that prevent uterine contractions * Steroids unless contraindicated * Transfer to unit with NICU facilities * Aim for vaginal delivery
48
Describe the prognosis of preterm labour?
* Possible neonatal morbidity from prematurity * Respiratory distress syndrome * Intraventricular haemorrhage * Cerebral palsy * Nutrition * Temperature control * Jaundice * Infections * Visual impairment * Hearing loss