Female Reproductive Flashcards
functions of female reproductive system
- ovaries produce secondary oocyte
- uterine tubes transport oocyte to uterus
- uterus is the site of implantation of fertilized ovum and dev’t of fetus and labour
- vagina is passageway for intercourse and childbirth
- mammary glands produce milk for newborn
ovaries
a pair of organs in the upper pelvic region about the size of almonds on either side of the uterus
- produce the hormones estrogen, progesterone, inhibin and relaxin
- produce gametes: secondary oocytes which mature into ova upon fertilization
histology of ovaries
superficial to deep
- germinal epithelium: squamous to low cuboidal
- tunica albuginea: dense irregular CT outside of ovary
- ovarian cortex: dense CT that contains follicles and stromal cells
- ovarian medulla: blood/lymphatic vessels, nerves (all entering at hilum) and loose CT
stages of follicular dev’t
primordial follicle primary follicle secondary follicle mature (graafian) follicle ovulation
corpus luteum
remnant of the mature follicle
- fills in with hormone secreting cells that help uterus develop and support more follicles developing
- breaks down blood clot
- stays for 2 weeks in unfertilized stage
corpus albicans
a white scar tissue let behind after corpus luteum is not needed and is degraded
primordial follicle
all the follicles are primordial when a baby is born
- has primary oocyte
- stromal cells start to organize when cell begins to develop and make some CT
- collagen fibers make up protein component of CT
primary follicle
at puberty, follicles begin to develop
- has primary oocyte
- zona pellucida: glycoprotein layer around primary oocyte
- granulosa cells: follicular cells multiply
- theca folliculi: organized stromal cells
secondary follicle
has primary oocyte
- corona radiata: granulosa cells sticking to zona pellucida
- antrum: cavity formed by granulosa cells secreting follicular fluid that grows as follicle matures
- theca folliculi becomes 2 layers: theca externa and theca interna
mature (graafian) follicle
primary oocyte still
- granulosa cells secrete inhibin which prevents all other follicles from developing further (they will degrade or wait until next year)
theca interna vs theca externa
in secondary oocyte
interna: creates cuboidal calls that secrete estrogen which further stimulates maturation of follicle
externa: CT made of collagen fibers and stromal cells
inhibin
- secreted by a mature and dominant follicle into bloodstream to prevent other follicles from also being released and maturing
- secreted by luteal cells after ovulation has occurred
ovulation
just before ovulation, the primary oocyte becomes a secondary oocyte, the side of the ovary bulges outward and basement membrane breaks open and the oocyte gets released into the pelvic cavity
- granulosa and theca interna cells morph into a glandular strucutre: luteal cells merge into corpus luteum and produce progesterone, relaxin and inhibin
uterine (fallopian) tubes
- narrow 10cm long tubes that extend from ovary and open to uterine cavity
3 regions: infundibulum, ampulla, isthmus
infundibulum region of uterine tube
funnel shaped 1st portion of uterine tube, nearest the ovary
fimbriae
found on the end of infundibulum region of uterine tube
- fingerlike projections that sweep the oocyte into the uterine tube
ampulla region of uterine tube
central region of the tube
- covers majority of the length
- fertilization usually occurs here
isthmus region of uterine tube
= narrow area
- the narrowest part of the tube that joins the uterus
histology of uterine tubes
3 layers:
- mucosa: ciliated simple columnar and peg cells (microvilli and secrete nutritious fluid)
- muscularis: inner thick circular, outer thin longitudinal smooth muscle (for peristalsis)
- serosa: outer serous membrane: visceral peritoneum
function of uterine tubes
events occurring in the uterine tubes are as follows:
- fimbriae sweep oocyte into tube
- cilia and peristalsis move it along
- sperm reaches oocyte in ampulla and fertilization can occur within 24 hours after ovulation and zygote reaches uterus in 6-7 days (blastocyst implants)
uterus
site of menstruation and development of fetus
- 7.5cm long by 5cm wide and 2.5 cm thick bc very muscular
3 regions: fundus, body and cervix
uterine fundus
- top portion, most muscular
cervix
- canal needs to widen to give birth
- interiorly contains uterine cavity accessed by cervical canal
broad ligament
created by a fold in the visceral peritoneum that attaches the uterus to pelvic cavity on either side
ovarian ligament
holds ovary onto uterus inside pelvic cavity
isthmus of uterus
narrowing portion of uterus towards cervix region