Female Reproduction Flashcards
At birth, what is the state the eggs are in?
At birth, a female’s ovaries contain 2-4 million eggs in meiotic arrest of which 400 will mature to ovulation.
What happens to eggs each month?
activity in ovary resumes with first meiotic division into secondary oocyte (only 400 eggs do this over lifespan)
How many polar bodies are produced during the development of an oocyte?
2 polar bodies
When does the ovum complete its 2nd meiotic division?
after fertilization
The female gamete after ovulation and prior to fertilization is:
A. Oogonia
B. Primary oocyte
C. Secondary oocyte
D. Ovum
C. Secondary oocyte
The first polar body contains:
A. 46 chromosomes, 2 chromatids
B. 46 chromosomes, 1 chromatid
C. 23 chromosomes, 2 chromatids
D. 23 chromosomes, 1 chromatid
C. 23 chromosomes, 2 chromatids
What hormone stimulates the granulosa cells?
FSH
What hormone stimulates the thecal cells?
LH
What is the inhibitory action of baseline levels of estrogen?
inhibits FSH and LH from anterior pituitary
inhibits GnRH from hypothalamus
What is the inhibitory action of inhibin?
inhibits FSH from anterior pituitary
What is the first day of the menstrual cycle?
First day of bleeding
On what day of the menstrual cycle does ovulation occur?
day 14
What causes the release of LH from the anterior pituitary?
A big burst of estrogen (from follicle)
What does the corpus luteum secrete?
Corpus luteum secretes estrogen, PROGESTERONE, and inhibin
What does the corpus luteum become if fertilization does not take place?
corpus albicans
Increased synthesis of estradiols is due to:
A. Proliferation of thecal cells
B. Proliferation of granulosa cells
C. Both
D. Neither
C. Both
Granulosa cells are producing aromatase
Thecal cells are producing androgens
aromatase + androgen = estradiol
What are the inhibitory effects of progesterone?
Inhibits GnRH and LH
What is the effect of estradiol on the uterus?
↑ cell proliferation & growth, ↑ contractility
What is the effect of estradiol on the fallopian tubes?
↑ ciliary activity & contractility
What is the effect of estradiol on the vagina?
↑ proliferation of epithelial cells
What is the effect of progesterone on the uterus?
↑ secretions ↓ contractility ↑ differentiation
What is the effect of progesterone on the fallopian tubes?
↑ secretions ↓ contractility
What is the effect of progesterone on the vagina?
↑ differentiation ↓ proliferation
What hormone dominates during the follicular phase?
estradiol