Female Physiology Flashcards

1
Q

androgens stimulate what cells

A

granulosa cells

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2
Q

estrogen inhibits what

A

GnRH
LH
FSH

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3
Q

Granulosa cells inbits

A

FSH secretion

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4
Q

What regulates thecal cells

A

LH

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5
Q

What regulates granulosa cells

A

LH and FSH

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6
Q

E2

A

estradiol

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7
Q

E1

A

estrone

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8
Q

E3

A

estriol

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9
Q

what hormone is predominant during pregancy

A

estriol (E3)

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10
Q

what hormone is predominant during menopause

A

estrone (E1)

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11
Q

what hormone is predominant during reproductive year

A

estradiol (E2)

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12
Q

how carbons does all estrogens have

A

18

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13
Q

Functions of Estrogen

A
  • maturation and 2nd sex characteristics
  • increase CNS excitablity
  • Stimulate endomerial prolif. and uterine growth
  • maintenanceof blood vessels and skin
  • increase plasma serum hormone bind globulin
  • reduce rate of bone re-adsorption
  • alter plasma lipds (increase HDL and tri., lower LDL)
  • enhanced blood coagulabilty
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14
Q

what point of the cycle is estrogen at its low point

A

menses

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15
Q

what stimulates hte growth of several preovulatory ovarian follicles

A

FSH and LH

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16
Q

LH act predominantly on

A

theca cells

17
Q

FSH act predominantly on

A

granulosa cells

18
Q

what inhibits FSH and LH

A

increase E2

19
Q

where does FSH and LH accumulate during prolong levels of E2

A

anterior pituitary

20
Q

What causes LH to surge

A

Temporary flip feed back from neg to pos. stims hypothalamusro release moreGnRH

21
Q

what does the LH surge cause

A

ovulation

22
Q

how long does the luteal phase last

A

begins at ovulation and last 14 days

23
Q

What inhibts the pituitary from releasing LH and FSH

A

elevated progesterone (and estrogen) in the blood

24
Q

What phase does the uterus change its lining

A

secretory phase

25
Q

What causes the changes in the lining of the uterus

A

progesterone

26
Q

after ovulation, what does the granulosa cell start to produce in the corpus luteum

A

progesterone

27
Q

Where are prgestin synthesized

A

overary testes and adrenal cortex from cholesterol

28
Q

carbon back bone of progestins

A

21

29
Q

Physiological effects of progesterone

A
  • prepares uterus for implant
  • devel. of secretory mech of breast
  • increase fat deposition
  • Decrease CNS excitabilty
  • increase insulin
  • increase aldoserone
  • increase body temp
  • decrease pC02
30
Q

what hormone is invouled with body weight and puberity

A

leption

31
Q

what could be cause of menopause

A

loss ininhibins (loss of inhibition for FSH

32
Q

what hormone at menopause is elevated

A

FSH

33
Q

upon implantation, trophoblast start secreting what

A

hCG, LH like

34
Q

what dies hCG prompts

A

the corpus luteum to continue expressing estrogens and progesterone

35
Q

what prevents menstruation

A

hCG