Female Pathology: vulva Flashcards
what structures are included in the vulva
- skin and mucosa that is external to hymen
- labia majora, labia minora, mons pubis, vestibule
what epithelium lines the vulva
squamous epithelium
What is Bartholin cyst
cystic dilation of Bartholin gland
Where is Bartholin gland located? What does it produce? and where does is drain
- each side of vaginal canal
- mucus-like fluid
- ducts into lower vestibule
what causes Bartholin cyst
inflammation and obstruction of gland
who usually gets Bartholin cyst
women of reproductive age
how does Bartholin cyst present clinically
unilateral, painful cyst
What is condyloma
watery neoplasm of vulvar skin
often large
What are common and less common causes of condyloma
common: HPV 6 or 11
less common: secondary syphilis ( condyloma latum)
Histologically, HPV-associated condylomas are characterized by what
Koilocytes
Do condylomas progress to carcioma
rarely
What is Lichen Sclerosis
thinning of epidermis and fibrosis (sclerosis) of dermis
clinical presentation of Lichen Sclerosis
white patch ( leukoplakia) with parchment-like vulvar skin
Lichen sclerosis is seen in who
postmenopausal women
what is a possible etiology for Lichen sclerosis
autoimmune
Is lichen sclerosis benign or malignant
Benign
- slightly increased risk for squamous cell carcioma
What is lichen simplex chronicus
hyperplasia of vulvar squamous epithelium
how does lichen simplex chronicus present
leukoplakia with thick, leathery vulvar skin
lichen simplex chronicus is associated with other conditions
chronic irritation and scratching
is lichen simplex chronicus benign or malignant
benign
no increased risk of squamous cell carcinoma
what is vulvar carcinoma
carcinoma arising from squamous epithelium lining vulva
how often does vulvar carcinoma present
rare
how does vulvar carcinoma present
leukoplakia
Etiology of vulvar carcinoma
HPV related or non HPV related
