Feline Vaccines

Question 1

What is the update on feline injection- site sarcomas?

Answer 1

Occurrence of this sequela remain infrequent and idiosyncratic

Question 2

What influences the quality of vaccine-induced immunity?

Answer 2

Patients environment, characteristics of the vaccine, pathogen and patient’s immune competence

Question 3

What is the primary target population of immunization?

Answer 3

Kittens

Question 4

What is the role of maternally derived antibodies (MDA) in terms of immunization?

Answer 4

MDA’s provide protection during early life but does interfere with active immunization by inhibiting IgG and neutralizing vaccine Ags

Question 5

Compared to puppies, do kittens have longer or shorter immunity from MDA?

Answer 5

Kittens have a shorter immunity from MDA (2w earlier than puppies)

Question 6

The best kitten vaccination protocol is to immunize every _____ weeks through ________ weeks of age

Answer 6

2-4w
16-18 wks of age

Question 7

In the past, it was the standard protocol to booster vaccines at 1 year of age after the kitten vaccine series; however, recent studies demonstrated otherwise. What is the current recommendations by WSAVA?

Answer 7

6 months of age

Question 8

When do you have to repeat kitten vaccination series?**

Answer 8

If more than 6w elapses between the two initial doses of the vaccines (other than rabies)

Question 9

Inactivated vaccines

Answer 9

Safer in pregnant cats and rapid onset of immunity

Question 10

Attenuated vaccines

Answer 10

Mimics natural immune response

Question 11

Recombinant vaccines

Answer 11

Vaccines created through manipulation of DNA of a pathogen in the lab with reduction in pathogen virulence

Question 12

Core v. non-core vaccines

Answer 12

Core: Recommended for cats
Non-core: Recommended based on individualized risk-benefit assessment

Question 13

Core vaccines for cats

Answer 13

FHV-1, FCV, FPV, rabies, FeLV (in cats younger than 1)

Question 14

Non-core vaccines for cats

Answer 14

FeLV, chlamydia felis and Bordetella Bronchiseptica

Question 15

Why is FIP vaccine not generally recommended

Answer 15

Because it should be administered at 16 weeks but kitten are infected with corona before that
No evidence that the vaccine induces protection

Question 16

Should we or not vaccinate cats with FIV/FeLV for upper respiratory infection?****

Question 17

Which type of FPV + FHV + FCV is considered the first choice for upper respiratory infection?

Answer 17

Parenteral attenuated live vaccine

Question 18

Why should the attenuated upper resp. vaccines be avoided for pregnant cats and kittens less than 4w of age?

Answer 18

Due to potential concern for cerebellar hypoplasia

Question 19

In shelters, what’s the recommended frequency of the boosters for upper resp. vaccines?

Answer 19

2 weeke

Question 20

Where should vets report vaccine adverse events?

Answer 20

Contact manufacturers of the vaccine
Then Center for Veterinary Biologics of the USDAs Animal Plant Health Inspection Service

Question 21

When do vaccine adverse events occur more frequently?

Answer 21

Within 30 days of vaccine admin

Question 22

What is the 3-2-1 rule?

Answer 22

Bx warranted if it remains present 3 months after vx, is large than 2 cm in diameter or increasing in size 1 month after vx

Question 23

Where should we vaccinate in cats?

Answer 23

Distal limbs and tail