Feline Lower Airway Disease Flashcards

1
Q

Which cats are commonly affected by feline asthma?

A

Young to middle ages cats but can be any age
If older cat be suspicious for:
* Hyperthyroidism
* Neoplasia
* Cardiac disease

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2
Q

Infectious causes of lower airway disease

A

Viral
Parasitic
Mycoplasma
Toxoplasma
(Bacterial is relatively uncommon)

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3
Q

Clinical history of feline asthma

A

Usually low grade chronic disease
* Coughing
* Wheezing
* Exercise intolerance

Can be very acute presentation (emergency)
* Dyspnoea
* Mouth breathing
* Tachypnoea

Episodic respiratory distress (paroxysmal

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4
Q

Why can a chronic disease such as feline asthma have acute presentation (emergency)

A

Cats are every good at masking clinical signs so don’t see until they are overwhelmed

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5
Q

URT disease physical exam

A

Laboured slow inspiration
Stridor (high wheezing)
Change in purr/vocalisation
ysphagia +/- salivation
Coughing/gagging
‘head shaking’ - nasal disease?

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6
Q

LRT disease exam

A

Laboured longer expiration
Expiratory push
Audible expiratory wheeze - due to bronchospasm, mucus, bronchial wall thickening
+/- paroxysmal cough

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7
Q

What is feline asthma?

A

Acute presentation
Reversible
Inhaled allergen
Airway hyperreactivity
Bronchoconstriction

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8
Q

What is chronic bronchitis

A

Response to infection or inhaled irritants
Airway damage
Excess mucus

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9
Q

Differences between feline asthma and chronic bronchitis

A

Aetiology different

Presentation and treatment the same

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10
Q

Pathogenesis of feline lower airway disease

A
  • Hyper-reactivity of bronchial smooth muscle
    ○ Type I hypersensitivity
    ○ Autonomic imbalance
    ○ Mucociliary imbalance
  • Acute bronchoconstriction in response to trigger
  • Inflammation of bronchial mucosal lining
    ○ Histamine and leukotriene release
  • Airway obstruction occurs due to:
    ○ Bronchoconstriction
    ○ Inflammation
    ○ Mucus plugs in narrowed bronchioles
  • Air trapping -> destruction of alveoli
  • End result is chronic damage
    ○ Irreversible situation due to remodelling
    ○ May see spontaneous rib fractures FROM COUGHING
  • Extreme acute deterioration
    ○ Rare cases develop pneumothorax
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11
Q

Differential diagnoses for tachypnoea

A

○ Stress/pain/fear response
○ CNS disease
○ Anaemia/hypovolaemia
○ Heatstroke
○ Cardiac disease
○ Respiratory disease
Airways or parenchyma
○ Pleural space disease
○ Mediastinal disease
○ Ruptured diaphragm/hernia

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12
Q

Diagnostic methods

A

Haematology and biochemistry
Thoracic radiography
THoracic ultrasound
CT
Faecal analysis for parasites
Bronchoscopy (CAREFUL)

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13
Q

Which is the most likely parasite in a cat

A

Aleurostrongylus abstrussis

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14
Q

Why would we not do a trans tracheal wash in a cat?

A

Tracheas are too narrow

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15
Q

Name some bronchodilators

A

Terbutaline
Salbutamol

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16
Q

Long term treatment method

A

Prednisolone for 2-3 weeks
Can then move onto fluticasone (corticosteroid)

17
Q

Why don’t use NSAIDs?

A

Prostaglandin is a bronchodilator so we don’t want to get rid of this in the lungs

18
Q

Side effects of prednisolone treatment

A

Iatrogenic diabetes
Treat with insulin