February 2025 Flashcards

1
Q

What is the most common cause of postpartum haemorrhage?

A

Uterine Atony

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2
Q

Fibroadenoma management

A

Depends on patient’s preference
- Can be safely left behind with
reassurance and periodic review.
- Surgery – excision done usually under
GA if patient wants.

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3
Q

Duodenal atresia features

A
  • Neonate w/ vomiting (after first feeds)
  • Down syndrome 5%
    distal obstruction to the papilla of Vater 80%
    -bilious vomiting
  • M > F
    -X-ray: ‘double-bubble’
  • drooling
  • abdominal distension (very late symptom)
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4
Q

Perthes features

A
  • Normal Caucasian boy
  • 4 and 10 years, peak incidence at 5 to 7 years
  • 15% bilateral
  • widening of joint hip space
    Hip pain result of necrosis of the involved bone
    -pain may be referred to the medial aspect of the ipsilateral knee or to the lateral thigh.
  • The quadriceps muscles and adjacent thigh soft tissues may atrophy, and the hip may develop adduction flexion contracture
  • antalgic gait with limited hip motion, or a Trendelenburg gate (abductor lurch).
  • Pain may be present with passive range of motion and
    limited hip movement, especially internal rotation and abduction
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5
Q

Intraductal Papilloma

A

Clinical Features:
1. Watery/Bloody discharge
2. Just 1 duct compromised

First Investigation:
1. PE.
2. US (<35yo)
Mammography (>35yo)

Best Investigations:
1. FNAC
2. Core Biopsy
3. Breast Ductography (specific)

Management: Surgery

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6
Q

Development of pubic hair

A

Girls: 8 years
Boys: 9 years

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7
Q

Paget’s disease management

A
  • lumpectomy (breast conserving surgery)
  • partial mastectomy or wide local incision
  • Total mastectomy only if indication of disease is severe
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8
Q

Management of px with breast cancer spread to several places in bones

A
  • anticancer therapy with hormonal treatment
  • chemotherapy
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9
Q

Ventricular septal defect (VSD)

A
  • holosystolic murmur at left sternal border
  • acyanotic
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10
Q

septic arthritis management

A
  • Joint drainage & debridement
  • IV antibiotics
  • orthopaedic surgeon referral
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11
Q

Complications of thyroglossal duct cyst (TDC)

A
  • Infection
    -Malignancy 1%
  • Overgrowth and pressure of the underlying
    structures.
  • Rupture and fistula formation
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12
Q

Posterior triangle of the neck mass

A

CCP
- Cystic hygroma
- Cervical rib
- Pancoast tumour
- (Naso/oropharyngeal squamous cell carcinomas)

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13
Q

3-4 years of age + kidney claw sign + abdominal mass does not cross midline

A

nephroblastoma (Wilm’s tumour)

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14
Q

Rinne test

A

AC>BC = Normal/SNHL
BC>AC= CHL

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15
Q

Developmental dysplasia (DDH) of the hip features

A
  • neonates from breech delivery
  • Female 6xt more likely
  • unilateral or bilateral (positive family hx)
  • Diminished abduction in flexion of the
    affected hip
  • Apparent inequality of legs: affected
    leg being shortened and externally rotated
  • Asymmetrical skin creases of the groin and
    thigh
  • ‘clicking’ on hip movements
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16
Q

Bacterial conjunctivitis in children school exclusion

A
  • Excluded until discharge has resolved
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17
Q

Weight: 1 standard deviation above/below the 50th percentile

A

Weight: overweight/underweight

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18
Q

kidney scarring investigation of choice in children

A

DMSA (gold standard)

  • Clinical suspicion of renal injury
  • Reduced renal function
  • Suspicion of VUR
  • Suspicion of obstructive uropathy on ultrasound in older toilet-trained children
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19
Q

Features of Paget’s disease

A
  • eczematous-looking
  • dry scabbing nipple rash
  • nipple ulceration
  • nipple skin thickening
  • dilated duct of the breast
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20
Q

Breast cancer screening age group

A
  • 50-74 (mammograms every two years)
  • Woman 40 years of age specifically asking due to family history of risk BC
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21
Q

Cervical masses in neonatal period

A
  • thyroglossal duct cyst (TDC)
  • teratomas
  • sternocleidomastoid tumours of infancy
  • vascular or lymphatic malformations.
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22
Q

Hypertrophic Pyloric Stenosis risk factors in children

A

-Formula feeding
-Male
-Caucasian background
-Firstborn
-Maternal smoking during pregnancy
-Positive family history
-Both erythromycin and azithromycin < 2weeks

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23
Q

slipped capital femoral epiphysis (SCFE) management

A
  • Cease weight-bearing and refer urgently.
  • lf acute slip, gentle reduction via traction is
    better than manipulation for prevention of
    later avascular necrosis.
  • Once reduced, perform pinning
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24
Q

Idiopathic (immune) thrombocytopenic purpura (ITP) in children management

A
  • If not bleeding: monitoring/observation
  • If bleeding: IVIG and corticosteroids (prednisone)
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25
Q

Mammary Duct Ectasia

A

Clinical Features:
- Unilateral
- Multiple ducts in the SAME breast
- Discharge: Sticky, toothpaste-like green

First Investigation: Mammography

Best Investigations: Ductal lavage (Cytology)

Management: Excisional biopsy

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26
Q

DMSA indications

A
  • Clinical suspicion of renal injury
  • Reduced renal function
  • Suspicion of VUR
  • Suspicion of obstructive uropathy on ultrasound in older toilet-trained children
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27
Q

murmurs that increase in
intensity when the venous return to the heart is
decreased:

A
  1. hypertrophic obstructive
    cardiomyopathy (HOCM)
  2. mitral valve prolapse
  3. venous hum (low-pitched continuous
    murmurs produced by blood returning from
    the great veins to the heart)
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28
Q

Perthes disease management

A
  • refer to surgeon

Surgeon will make call on conservative or surgical
- conservative: brace
- surgical: osteotomy/femoral head fixation, hip replacement worst case

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29
Q

Hypertrophic Pyloric Stenosis features in children

A
  • 2 and 6 weeks of age
  • gastric outlet narrowing
  • projectile vomiting a few minutes after feeding
  • non bloody, non bilious vomiting (may have coffee ground appearance due to repeated vomiting)
  • delayed capillary refill > 2 seconds
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30
Q

Renal scarring in children

A
  • Recurrent urinary tract infections (more than
    2 times during childhood)
  • Dimercaptosuccinic acid scintigraphy (DMSA) - Gold Standard
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31
Q

Breast Lumps

A

Clinical Features: Smooth margins

First Investigation:
1. PE.
2. US (<35yo)
3. Mammography (>35yo)

Best Investigations:
1. FNAC
2. Core Biopsy

Management:
1. Observation.
2. Excision

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32
Q

Paget’s disease differential dx

A
  • Ductal carcinoma in situ
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33
Q

Innocent murmur

A

7S
-soft
- systolic
- short duration
- sounds (S1 &S2)
- symptomless
- Special tests normal (X-ray, ECG)
- Standing/Sitting changes (not fixed) (increased when supine)

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34
Q

Tanner stages

A

I:
- 0–15 years
- None
II:
- 8–15 years
- Commencement of puberty
- Breast budding first
- Pubic hair
- Scrotal/Testicular growth, penis growth after a year
III:
- Increase in hair and pigmentation

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35
Q

Anterior triangle of the neck mass

A

BCC
- Branchial cyst
- Carotid body tumour
- Carotid aneurysm

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36
Q

Down syndrome in children

A
  • short stature
  • microcephaly
  • centrally placed hair whorl
  • small ears
  • redundant skin on the nape of the neck
  • flat nasal bridge
  • Cardiac lesions 30% to 50% (endocardial cushion defect, VSD, tetralogy of Fallot (all 30%)
  • Duodenal atresia
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37
Q

kidney scarring features in children

A
  • one kidney smaller than the other
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38
Q

Fibroadenoma features

A
  • Most common benign breast lump
  • 20-30 years
  • Well defined, round with even surface,
    regular margins, rubbery or soft in
    consistency, freely mobile, non-tender
  • Does not increase the risk of cancer
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39
Q

Müllerian agenesis [incomplete]
Check more on clinical features of female agenesis

A
  • Female gonads do not secrete Müllerian-inhibiting factor (MIF)
  • Male testes secrete MIF
  • empty scrotum
  • testes are impalpable in inguinal canal
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40
Q

Pathological murmurs features

A

Family hx of sudden cardiac death or congenital heart disease
- in utero exposure to certain medications (lithium) or alcohol
- Maternal diabetes mellitus
- History of rheumatic fever
- History of Kawasaki disease

  • Grade 3/6 or higher murmurs
  • Harsh quality
  • Abnormal S2
  • The presence of a systolic click
  • Increased intensity with decreased venous
    return (e.g., when the patient stands)
  • The patient has any symptoms that could be
    related to a cardiac condition (e.g. shortness
    of breath, chest pain, poor feeding, etc.)
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41
Q

Atrial Septal Defect (ASD)

A
  • acyanotic
  • mid-systolic murmur at the pulmonary area, a split-second heart sound and a loud P2

2 main types:
- Ostium Primum: most dangerous type, can lead to pulmonary hypertension and heart failure, Prophylactic antibiotics recommended
- Ostium Secundum: most common type, e hole is higher in the septum, not serious, symptoms uncommon in infancy

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42
Q

Idiopathic (immune) thrombocytopenic purpura (ITP) in children features

A
  • preceding viral infection
  • s frequently < 20,000/μL
  • other lab tests normal
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43
Q

septic arthritis in children

A
  • S aureus
  • joint aspiration
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44
Q

Hypertrophic Pyloric Stenosis in children management

A

Initial: Fluid resuscitation
Best: Ramstedts Pyloromyotomy

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45
Q

Developmental dysplasia (DDH) of the hip dx

A

Barlow test —‘telescoping’ movements in the long axis of the flexed and abducted thighs.

Ortolani test — flexed hips are abducted. thighs are the grasped between the thumbs in front and other fingers behind. The child’s knees are flexed and hip flexed to a right
angle. **positive sign makes audible and palpable ‘jerk’ or ‘clunk’ (not a click). **
- Ortolani and Barlow tests but is usually negative after two months
- Ultrasound is excellent especially up to 3-4 months

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46
Q

Fibroadenoma

A

Clinical Features: Mobile, non-tender

First Investigation: US

Best Investigations:
1. FNAC.
2. Core Biopsy

Management: Reassure/Review in 3 months

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47
Q

Most appropriate step in management of postpartum haemorrhage after oxytocin and manual stimulation?

A

Ergometrine (help uterus contract)

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48
Q

slipped capital femoral
epiphysis (SCFE) clinical features

A
  • Overweight adolescent of 10 to15 years
  • bilateral in 20%
  • Limp and irritability of hip on movement
  • Knee pain — referred from the affected hip
  • On flexion of the hip, it rotates externally. Hip
    is often in external rotation on walking.
  • Most movements restricted, especially
    internal rotation.
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49
Q

anal fissure features [incomplete]

A
  • passage of hard stools
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50
Q

Hepatoblastoma clinical features

A

-<5 years
- mass in right upper quadrant
- abdominal distension
- right-sided abdominal pain
- familial adenomatous polyposis high risk
- lost appetite and weight
- vomiting and jaundice (very rare)

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51
Q

Midline of the neck mass

A

TTD
- Thyroid nodule
- Thyroglossal cyst
- Dermoid cyst

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52
Q

infant < 2 years + low-grade fever + abdominal distension + loss of appetite + limb pain + abdominal mass that crosses the midline

A

Neuroblastoma
- originates from adrenal glands

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53
Q

most common congenital heart disease in infants?

A

Ventricular Septal Defect (VSD) 1 in 100 Australian infants

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54
Q

Weight: 2 standard deviation above/below the 50th percentile

A

Weight: obese/severely underweight

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55
Q

Patent ductus arteriosus. (PDA)

A

-acyanotic
- pansystolic machinery murmur (harsh) at the left sternal border
- wide pulse pressure.
- Definite treatment surgical closure

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56
Q

Weber’s test

A

Normal = lateralizes equally to both ears

CHL= lateralizes to abnormal ear

SNHL= lateralizes to the normal ear

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57
Q

Bacterial conjunctivitis in children

A
  • gonorrhoea: fast and aggressive (3 and 7 days after birth)
  • chlamydia: slow and less aggressive (end of 1st week - 1 month after birth)
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58
Q

Most at risk demographic for developing iron deficiency?

A

toddlers (weaning off breast milk)

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59
Q

Tetralogy of Fallot (TOF)

A

4 defects
- blood going from left to right ( acyanotic)
- all have VSD (systolic murmur)
- pulmonary stenosis
- right ventricle hypertrophy
- overriding aorta

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60
Q

anal fissure

A
  • most common cause of painful rectal bleeding in children
  • associated with constipation
  • bright blood on the
    surface of stool, on the nappy or toilet paper
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61
Q

Management of px with breast cancer spread to one area of bone

A
  • Radiotherapy
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62
Q

Colon polyp

A
  • benign hamartomas
  • ages 2 and 8 years, peak at 3 to 4 years
  • mostly painless
    rectal bleeding
    palpable polyp
    on rectal examination >60%
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63
Q

Transposition of the great arteries (TGA)

A
  • central cyanotic after 10-12 hours
    Aorta and pulmonary arteries are reversed
  • no murmur as there is no hole
  • prescribe PG e1
  • definite treatment: surgery to correct the transposition
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64
Q

adolescent + fever >38.5C + ↑WBC, ESR, CRP + Acute painful, tender and warm joint + limited movement + refusal to bear weight

A

Septic arthritis

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65
Q

Upper Limb nerve roots

A

Brachial Plexus Roots C5-T1:
“Randy Travis Drinks Cold Beer”
* Roots → Trunks → Divisions → Cords → Branches

  • C5: Deltoid (shoulder abduction), biceps (flexion).
  • C6: Biceps reflex, wrist extension.
  • C7: Triceps reflex, wrist flexion, finger extension.
  • C8: Finger flexion, grip strength.
  • T1: Intrinsic hand muscles (fine motor).
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66
Q

C5 nerve root

A

Muscle: Biceps
Reflex: Biceps
Motor action: Shoulder abduction, elbow flexion
Sensory region: Lateral upper arm

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67
Q

C5 nerve root lesion

A
  • Weak shoulder abduction
  • diminished biceps reflex
  • numbness over the lateral upper arm
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68
Q
  • Weak shoulder abduction
  • Diminished biceps reflex
  • Numbness over the lateral upper arm
A

C5 nerve root lesion

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69
Q

C6 nerve root:

A
  • Motor Functions: Wrist extension, elbow flexion.
  • Reflex: Brachioradialis reflex.
  • Sensory Area: Lateral forearm, thumb, index finger.
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70
Q

C6 nerve root lesion

A
  • Weakness in wrist extension
  • diminished brachioradialis reflex
  • numbness over thumb and lateral forearm.
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71
Q
  • Weakness in wrist extension
  • diminished brachioradialis reflex
  • numbness over thumb and lateral forearm.
A

C6 nerve root lesion

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72
Q

C7 Nerve Root

A
  • Motor Functions: Elbow extension, wrist flexion, finger extension.
    • Reflex: Triceps reflex.
    • Sensory Area: Middle finger.
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73
Q

C7 nerve root lesion

A
  • Weakness in elbow extension
  • diminished triceps reflex
  • numbness over the middle finger.
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74
Q
  • Weakness in elbow extension
  • diminished triceps reflex
  • numbness over the middle finger.
A

C7 nerve root lesion

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75
Q

C8 Nerve Root

A
  • Motor Functions: Finger flexion (grip strength).
    • Reflex: None.
    • Sensory Area: Medial forearm, ring and little fingers.
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76
Q

C8 nerve root lesion

A
  • Weakness in finger flexion and grip
  • numbness over medial forearm and little finger.
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77
Q
  • Weakness in finger flexion and grip
  • numbness over medial forearm and little finger.
A

C8 nerve root lesion

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78
Q

T1 Nerve Root

A
  • Motor Functions: Finger abduction/adduction (intrinsic hand muscles).
    • Reflex: None.
    • Sensory Area: Medial upper arm.
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79
Q

T1 nerve root lesion

A
  • Weakness in finger flexion and grip
  • numbness over medial forearm and little finger.
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80
Q
  • Weakness in finger flexion and grip
  • numbness over medial forearm and little finger.
A

T1 nerve root lesion

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81
Q

Median Nerve

A
  • Motor Functions: Wrist flexion, forearm pronation, flexion of thumb, index, and middle fingers; thumb opposition.
  • Sensory Area: Palmar surface of the thumb, index and middle fingers, and half of the ring finger.
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82
Q

Median nerve lesion

A
  • Proximal lesion: “Ape hand” deformity, weak forearm pronation, wrist flexion.
  • Distal lesion: “Hand of benediction” (can’t flex index and middle fingers when making a fist).
  • Sensory: loss of sensation over the thumb, index and middle fingers, and half of the ring finger
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83
Q
  • Proximal lesion: “Ape hand” deformity, weak forearm pronation, wrist flexion.
  • Distal lesion: “Hand of benediction” (can’t flex index and middle fingers when making a fist).
  • Sensory: loss of sensation over the thumb, index and middle fingers, and half of the ring finger
A

Median nerve lesion

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84
Q

Ulnar Nerve

A
  • Motor Functions: Finger abduction/adduction (interossei), flexion of medial fingers, wrist flexion (ulnar deviation).
    • Sensory Area: Medial 1½ fingers (palmar and dorsal).
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85
Q

Ulnar nerve lesion

A
  • Proximal lesion: “Claw hand” (incomplete flexion of medial fingers), weak grip.
  • Distal lesion: Complete claw hand.
  • Sensory loss over medial 1½ fingers.
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86
Q
  • Proximal lesion: Incomplete flexion of medial fingers, weak grip.
  • Distal lesion: Complete flexion of medial fingers, weak grip.
  • Sensory loss over medial 1½ fingers.
A

Ulnar nerve lesion

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87
Q

Axillary Nerve

A
  • Motor Functions: Shoulder abduction (deltoid).
    • Sensory Area: Lateral shoulder.
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88
Q

Axillary nerve lesion

A
  • Weakness in shoulder abduction (15°–90°)
  • numbness over lateral shoulder.
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89
Q
  • Weakness in shoulder abduction (15°–90°)
  • numbness over lateral shoulder.
A

Axillary nerve lesion

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90
Q

Musculocutaneous Nerve

A
  • Motor Functions: Shoulder abduction (deltoid).
    • Sensory Area: Lateral shoulder.
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91
Q

Musculocutaneous Nerve lesion

A
  • Weakness in elbow flexion and forearm supination
  • sensory loss over lateral forearm.
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92
Q
  • Weakness in elbow flexion and forearm supination
  • sensory loss over lateral forearm.
A

Musculocutaneous Nerve lesion

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93
Q

Anterior Interosseous Nerve

A
  • Motor Functions: Flexion of distal thumb and index finger.
    • Sensory Area: None.
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94
Q

Anterior Interosseous Nerve lesion

A

Weak pinch sign (inability to form “OK” sign).

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95
Q

Weak pinch sign

A

Anterior Interosseous Nerve lesion

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96
Q

Anterior interosseous nerve is a branch of which nerve?

A

Median nerve

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97
Q

Posterior Interosseous Nerve

A
  • Extends the wrist and fingers (except for the brachioradialis and extensor carpi radialis longus).
  • Key muscles: Extensor digitorum, extensor indicis, extensor digiti minimi, extensor carpi ulnaris, extensor pollicis longus/brevis, abductor pollicis longus.
  • Sensory Area: None (purely motor nerve).
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98
Q

Posterior Interosseous Nerve lesion

A
  • Weakness in finger and thumb extension.
  • Wrist extension preserved (extensor carpi radialis longus remains functional).
  • No sensory loss.
  • Common clinical sign: “Finger drop” (inability to extend the MCP joints of the fingers).
99
Q
  • Weakness in finger and thumb extension.
  • Wrist extension preserved (extensor carpi radialis longus remains functional).
  • No sensory loss.
  • Common clinical sign: “Finger drop” (inability to extend the MCP joints of the fingers).
A

Posterior Interosseous Nerve lesion

100
Q

Posterior Interosseous Nerve is a branch of which nerve?

A

Deep branch of the radial nerve

101
Q

Lower Limb nerve roots

A
  • L2-S1:
    “I Get Lunch From Some People”
    Iliopsoas → Gluteus medius → Lower limb flexors → Foot dorsiflexors → Sole of foot.
    • L2-L4: Quadriceps (knee extension), hip flexors.
    • L5: Ankle dorsiflexion (tibialis anterior), great toe extension (extensor hallucis longus).
    • S1: Plantar flexion (gastrocnemius), ankle reflex.
102
Q

Fitness to drive Acute MI private

A

at least 2 weeks

103
Q

Fitness to drive Acute MI commercial

A

at least 4 weeks

104
Q

Fitness to drive CABG private

A

at least 4 weeks

105
Q

Fitness to drive CABG commercial

A

at least 12 weeks (3 months)

106
Q

Fitness to drive PCI private

A

at least 2 days

107
Q

Fitness to drive PCI commercial

A

at least 4 weeks

108
Q

Fitness to drive Paroxysmal arrhythmias (supraVT, atrial flutter, idiopathic VT) commercial

A

at least 4 weeks

109
Q

Fitness to drive cardiac arrest private

A

at least 6 months

110
Q

Fitness to drive cardiac arrest commercial

A

at least 6 months

111
Q

Category 2 Colorectal cancer risk

A

Moderate risk
2x-4x higher than average risk
One 1st degree relative < 60 years at dx
OR
One 1st degree relative AND >One 2nd degree diagnosed at any range
OR
Two 1st degree relatives diagnosed at any age

112
Q

Category 1 Colorectal cancer screening

A
  • iFOBT every 2 years after 45 years to 74
  • low-dose (100 mg) aspirin daily should be considered from age 45 to 70
113
Q

Category 2 Colorectal cancer screening

A
  • Colonoscopy every 5 years starting at 10 years younger than the earliest age of diagnosis in 1st degree relative

OR age 50, whichever is earlier, to age 74.

  • CT colonography if clinically indicated
  • Low dose aspirin (100mg)
  • Update history
114
Q

Category 3 Colorectal cancer risk

A

High risk
Two 1st degree relatives AND One 2nd degree relative diagnosed < 50
OR
Two 1st degree relatives + > Two 2nd degree relative diagnosed at ANY age
OR
> Three 1st degree relatives diagnosed at ANY age

115
Q

Category 3 Colorectal cancer screening

A
  • Colonoscopy every 5 years starting at 10 years younger than the earliest age of diagnosis of colorectal cancer in a first-degree relative
    OR
    age 40, whichever is earlier, to age 74.
  • CT colonography if clinically indicated
  • Low dose aspirin (100mg)
  • Update history
116
Q

Category 1 Colorectal cancer risk

A
  • Near average risk if they have no family history of colorectal cancer
  • Above-average risk 1 1st degree relative > 60 years at dx
117
Q

Horner’s syndrome triad

A

Ptosis + Myosis + anhidrosis

118
Q

Ptosis + Myosis + anhidrosis

A

Horner’s syndrome

119
Q

ptosis + mydriasis

A

3rd CN palsy

120
Q

Most common cause 3rd CN palsy

A

Diabetic neuropathy

121
Q

diabetic neuropathy treatment

A

TCA

122
Q

clock drawing test assesses

A

severity of dementia

123
Q

clock drawing test

A

Frontal and Temporo-parietal functioning

124
Q

Permanent commercial driving restriction

A
  1. stable angina
  2. ICD (defibrillator)
125
Q

occupational therapist / ophthalmologist referral to drive

A

persistent hemianopia after stroke

126
Q

medications avoided in patients with rest less leg syndrome

A

– Metoclopramide (dopamine antagonists)
– Droperidol (dopamine antagonists)
– Lithium
– Naloxone (opioid antagonist)
– Antidepressants that increase serotonin levels

127
Q

ataxia + falls + past pointing + positive Romberg’s sign
+ nystagmus

A

Cerebellar stroke

128
Q

restless leg syndrome dx

A

clincal + Iron studies

129
Q

restless leg syndrome treatment

A

Dopamine agonist:
- ropinirole
- levodopa

130
Q

Alzheimer’s vs Fronto-temporal dementia

A
  • behavioural change early in fronto-temporal
131
Q

6th nerve palsy diseases

A
  • diabetes
  • Meningitis
  • multiple sclerosis
  • Wernicke’s encephalopathy
  • nasopharyngeal tumour
132
Q

“raccoon eyes” + blood behind the ears + mastoid ecchymosis (battle)

A

Basilar skull fracture

133
Q

vascular dementia treatment

A
  • prevent strokes
  • control hypertension
134
Q

abrupt onset of right face and hand weakness +
disturbed speech production, + a right homonymous hemianopsia

A

Left middle cerebral artery occlusion

135
Q

fluctuating level of consciousness + trivial force

A

Subdural hematoma

136
Q

head trauma + no loss of consciousness + deteriorating a few hours/days later

A

epidural hematoma

137
Q

Visual hallucinations + Parkinsonism +
+Fluctuation in the mental state

A

Lewy body dementia

138
Q

A headache exacerbated by coughing, sneezing or straining

A

brain tumours and raised intracranial pressure

red flag

139
Q

TIA 1st line treatment

A

Aspirin + dipyridamole

140
Q

Epileptic px planning to conceive + seizure free 2 years

A

Gradually cease anti-epileptic over 6 months

141
Q

vascular dementia memory treatment

A

acetylcholinesterase inhibitor (donepezil)

142
Q

Horner’s syndrome + nystagmus + facial sensory deficit + side of the body sensory deficit

A
  • posterior inferior cerebellar artery infarct (PICA)
  • lateral medullary syndrome (Wallenberg syndrome)
143
Q

contralateral hemiparesis + contralateral homonyms hemianopia + aphasia + sensory neglect

A

middle cerebral artery lesion (MCA)

144
Q

vascular dementia features

A

-Sudden onset of memory decline after a stroke with step-wise deterioration
-Variable cognitive impairment and emotional lability.
-Gait abnormalities.
-Urinary dysfunction.
-Parkinsonian motor features.
-Vascular lesions on MRI/CT.

145
Q

Alzheimer EEG

A

Generalized background slowing

146
Q

Alzheimer’s lobe atrophy

A

frontotemporal lobe atrophy

147
Q

Nerve injury - Clavicular

A

Brachial Plexus - Subclavian artery

148
Q

Nerve injury - anterior GH dislocation

A

N.axillaris

149
Q

Nerve injury - Surgical neck of humerus

A

N.axillaris

150
Q

Nerve injury - Midshaft humerus

A

N.radialis

151
Q

Nerve injury - medial epicondyle

A

N.ulnaris

152
Q

Nerve injury - greater tuberosity of the humerus

A

N.axillaris

153
Q

Nerve injury - Supracondylar humerus

A

Median nerve - brachial artery

154
Q

Nerve injury - Colles

A

N.median

155
Q

Nerve injury - ERB

A

Brachial plexus – high: C5 – C6

156
Q

Nerve injury - Klumpke

A

Brachial plexus – low: C8 – T1

157
Q

Biceps reflex

A

C5/6

158
Q

Supinator -Brachioradialis reflex

A

C5/6

159
Q

Triceps reflex

A

C7

160
Q

Injury Ulnar nerve - at wrist

A

Sensory
* numbness in the little and ring fingers
Motor
* weakness of abduction of his little finger
* weakness of flexion of the terminal
phalanx of his little and ring fingers

161
Q

Myotomes - upper limb

A

C4 = shoulder shrugs
C5 = Shoulder abduction and elbow flexion
C6 = Wrist extension
C7 = Elbow extension and wrist flexion
C8 = Thumb extension and fingers flexion
T1 = Finger abduction

162
Q

Clavicle Fracture

A
  • Fall onto affected shoulder
  • Pat is supporting arm which is in full adduction
163
Q

Clavicle Fracture - Things to look for

A
  • Careful NEUROVASCULAR examination
  • skin integrity to r/o open fracture
  • lung fields to r/o apical lung injury
164
Q

Clavicle Fracture - Classification

A
  • middle third
  • lateral third
  • medial third
165
Q

Clavicle Fracture - Middle third

A
  • 80%
  • Defined by shortening/comminution/angulation

MX
* Broad arm sling to support limb for 2 weeks or untilcomfortable.Regular analgesia as required

166
Q

Clavicle Fracture -Lateral third

A
  • 15%
  • Around and lateral to
    coracoclavicular Ligaments

Mx
* If undisplaced,no reduction required
* If displaced,refer
* Broad arm sling to support limb for 2 weeks or until
comfortable
Regular analgesia as required

167
Q

SIADH in children

A
  • hyponatremia
  • excessive amount of ADH from hypothalamus-pituitary
168
Q

Hyponatremia in children types

A

Dehydration: hypernatremia
Cardiac: Pseudohyponatremia
Addisons:
- Low aldosterone
- Hyperkalaemia
- hypotension

169
Q

SIADH in children symptoms

A
  • mental changes (confusion, memory problems)
  • seizures or worst case, coma
  • nausea and vomiting
  • headache
  • problems with balance
170
Q

SIADH in children causes

A
  • type 2 DM medication:
  • antiepileptic
  • antidepressant
  • surgery under general anaesthesia
  • brain disorders, injury, infections, stroke
  • lung disease (pneumonia, tuberculosis, cancer, chronic infections)
  • cancer of lung, small intestine, brain, leukaemia
171
Q

Hyponatraemic seizures in children

A
  • increasing irritability
  • increasing lethargy, - increasing tonic-clonic generalised
    seizures
  • respond poorly to conventional anticonvulsants (phenytoin, phenobarbitone)
  • address hyponatraemia by 3% NaCl solution
172
Q

Hypernatremia in children appearance and initial management

A
  • “doughy” skin
  • Isotonic (normal) saline for an initial bolus
173
Q

Addison’s disease in children

A
  • 21-hydroxylase deficiency
  • Dehydration, hypotension, and shock
  • hyponatraemia with hyperkalaemia
174
Q

List of autosomal dominant diseases

A

D -dystrophy myotonia
O - osteogenisis imperfecta
M - Marfan’s
I - intermittent porphyria
N - Noonan’s
A - achondroplasia, familial adenomatous polyposis (FAP)
N - neurofibromatosis
T - Tuberous sclerosis

V- Von Willebrand
H - Huntington’s HNPCC
H - hereditary spherocytosis
H- familial hypocholesteraemia
R - retinoblastoma

175
Q

List of autosomal recessive diseases

A

A - albinism
B - thalassaemia
C - cystic fibrosis
D - deafness
E - emphysema
F - Friederich’s ataxia (trinucleotide test, repeat GAA)
G - Gaucher’s disease
H Hemochromatosis, homocystinuria

S - sickle cell
P - phenylketonuria
N - Wilson’s
X - xeroderma pigmentosa

176
Q

List of X-linked recessive diseases

A

D- diabetes insipidus
D - Duchenne’s
C - colour blindness
C - chronic granulomatous disease (membranous type)
F - Fabry’s disease (alpha- glucosidase deficiency)
F - fragile X syndrome (Martin Bell Syndrome)
2 blood - haemophilia. G6PD
2 syndrome Lesch Nylon syndrome, Wiskots Aldrich yndrome

177
Q

Ostoporosis RISK FACTORS

A

 Diet- low in calcium

 Low BMI < 19

 Lack of exercise

 Inadequate exposure to sunlight

 SAD and excessive coffee intake

 Medications: glucocorticoids, anticonvulsants (phenothiazines), GnRh, aromatase inhibitors (Letrozole, Anastrozole, Exemestane), heparin, Depo, thiazolidinedions (glitazones), PPI’s

 Medical conditions: hyperthyroidism, hyperparathyroidism, chronic liver or renal disorders, rheumatoid arthritis, coeliac disease

 Menopause

 Family history

178
Q

Ostoporosis First Investigation

A

25 hydroxy Vitamin D

179
Q

Ostoporosis Best Investigation

A

DEXA Scan (Don’t take Ca 24 hours before)

  • T-score:
    > -1: Normal,
  • 0.9 to -2.4: Osteopenia
    < -2.5: Osteoporosis
  • Z score: ≤ -2: Investigation for underlying causes
180
Q

Osteoporosis CRITERIA FOR TREATMENT

A

 Any man or woman with spine or hip fractures after minimal trauma even if the T score is more than -2.5. Treatment may be initiated without confirmation of low bone mineral density.

 No fracture but score < or equal to -2.5 if risk factors are present

 Osteoporosis due to secondary causes

 Treatment with medications has to be started along with Calcium and Vitamin D supplementation
 1200- 1500 mg/day of calcium
 800- 2000 IU/day of Vitamin D

Notes: Medications increase bone density in the hip approximately by 1-3% and in the spine by 4-8% over 3-4 years

181
Q

Osteoporosis FIRST-LINE Treatment

A
  1. Bisphosphonates
    - Alendronate
    - Risedronate
    - Zoledronic Acid
  2. Denosumab
  3. Strontium ranelate
  4. Raloxifene
  5. MHT
182
Q

Osteoporosis SECOND-LINE Treatment

A

Teriparatide:

  • Is a recombinant parathyroid hormone.
  • Stimulates bone-forming cells.
  • Only if other treatments fail.
  • Given as daily injections subcutaneously for 18 months.

INDICATIONS: > 1 symptomatic new fracture after 12 months of biphosphonate or if T score is ≤-3

183
Q

Osteoporosis FIRST-LINE Treatment: BISPHOSPHONATES Zoledronic Acid

A

Annual infusion for a maximum of 3 years.

Used if patients have Oesophagitis.

Vitamin D levels should be corrected to 50nmol/L before starting the treatment.

184
Q

Osteoporosis FIRST-LINE Treatment: Denosumab

A
  • Monoclonal antibody against osteoclast.
  • Given as 6 monthly injections subcutaneously for 36 months.
  • No gastrointestinal side effects.
  • But increases hypocalcemia.
185
Q

Osteoporosis FIRST-LINE Treatment: Strontium ranelate

A

Given orally 2 grams/day.

Should not be given with calcium supplements.

Reserved for severe osteoporosis because can cause MI

  • Contraindications:
  • DVT
  • Prolonged immobilisation
186
Q

Osteoporosis FIRST-LINE Treatment: Raloxifene

A
  • Selective estrogen receptor modulator
  • Oestrogen-like effect on bone but antagonistic for uterus and breast.
  • Can be considered as second-line treatment for postmenopausal women with osteoporosis at risk of breast cancer.
  • Reduces risk of vertebral fractures.
187
Q

Osteoporosis FIRST-LINE Treatment: MHT

A

In peri or postmenopausal women with osteoporosis associated with other menopausal symptoms

188
Q

OSTEOPENIA CRITERIA FOR TREATMENT

A

T score between -1 and -2.5 without minimal trauma fracture

Treat with calcium and Vitamin D supplementation and lifestyle modifications:
 1200- 1500 mg/day of calcium
 800- 2000 IU/day of Vitamin D

189
Q

Osteoporosis Treatment Follow-up

A

Repeat DEXA in 2 years.

Every year if medication is changed, termination of the treatment or high-risk patient.

190
Q

Osteopenia Follow-up

A

Repeat DEXA every 2 - 5 years

191
Q

Osteoporosis Treatment: BISPHOSPHONATES General Features

A
  • Decrease bone loss and increase mineral density.
  • Measure Vit D and RFT before starting the treatment.
  • Useful for vertebral & non-vertebral fractures.
  • Contraindicated in pregnancy because it’s teratogenic.
  • Side Effects: GI discomfort, oesophagitis, and jaw necrosis
192
Q

Osteoporosis FIRST-LINE Treatment: BISPHOSPHONATES Alendronate & Risedronate

A
  • Alendronate - weekly dose
  • Risedronate - daily/weekly/monthly

For 5 to 10 years in postmenopausal women.

193
Q

OSTEOPOROSIS
Treatment for people with special circumstances: Corticosteroid therapy

A

All people above 50 years on corticosteroid therapy of 7.5 mg/day for at least 3 months with a T score of -1.5 or less have to be given bisphosphonates for the duration of therapy.

  • First-line: Alendronate and risedronate with adjuvant Calcium and Vit D.
  • Second-line: Zoledronic acid.
194
Q

OSTEOPOROSIS
Treatment for people with special circumstances: Renal impairment

A

Raloxifene or Denosumab.

195
Q

Non- cardiac surgery clopidorel

A

Cease 5 days prior

196
Q

Non- cardiac surgery ticagrelor

A

Cease 5 days prior

197
Q

Coronary artery bypass graft aspirin

A

continue through surgery

198
Q

Coronary artery bypass graft clopidogrel

A

Cease 5 days prior

199
Q

Coronary artery bypass graft Prasugrel

A

Cease 5-10 days prior

200
Q

Coronary artery bypass graft ticagrelor

A

Cease 5 days prior

201
Q

Spinal, intercranial, TURP, extraocular, plastic surgery asipirin

A

Cease 7-10 days prior

202
Q

Spinal, intercranial, TURP, extraocular, plastic surgery clopidogrel

A

Cease 5 days prior

203
Q

Spinal, intercranial, TURP, extraocular, plastic surgery prasugrel

A

Cease 5-10 days prior

204
Q

Non- cardiac surgery aspirin

A

Continue through surgery

205
Q

Spinal, intercranial, TURP, extraocular, plastic surgery ticagrelor

A

Cease 5 days prior

206
Q

Px < 3 doses or uncertain clean wound

A

DTPa/ ADT or combo: YES
Tetanus immunoglobulin: No

207
Q

Px < 3 doses or uncertain dirty wound

A

DTPa/ ADT or combo: YES
Tetanus immunoglobulin: YES

208
Q

Px > 3 doses > 10 years dirty wound

A

DTPa/ ADT or combo: YES
Tetanus immunoglobulin: No

209
Q

Px > 3 doses >10 years clean wound

A

DTPa/ADT: YES
Tetanus immunoglobulin: No

210
Q

Px > 3 doses 5-10 years dirty wound

A

DTPa/ADT or combo: YES
Tetanus immunoglobulin: No

211
Q

Px > 3 doses 5-10 years clean wound

A

DTPa/ADT or combo: No
Tetanus immunoglobulin: No

212
Q

px immunised > 3 doses < 5 years dirty wound

A

DTPa/ADT or combo: No
Tetanus immunoglobulin: No

213
Q

px immunised > 3 doses < 5 years clean wound

A

DTPa, ADT or combo: No
Tetanus immunoglobulin: No

214
Q

septic arthritis management

A
  • IV antibiotics (flucloxacillin) for 2 weeks
  • Oral antibiotics after 6 weeks
215
Q

hip joint degeneration affected movement

A

Internal rotation

216
Q

injuries warranting knee X-ray in children

A

– Isolated patellar tenderness.
– Tenderness at the head of the fibula.
– Inability to flex at 90 degrees.
– Inability to bear weight immediately after trauma and in an emergency

217
Q

‘twinge’ or sudden pain + Medial Joint line tenderness + able to continue activity with some discomfort

A

Medial meniscus tear

218
Q

Medial meniscus tear investigation

A
  • barefooted with the knee flexed to 20 degrees and rotates the body
    and knee three times internally and externally (Thessaly test) most useful
    Flexion/rotation test (McMurray test) for screening
219
Q

volleyball and baseball injury + flexion deformity + inability to actively extend finger

A

Mallet finger

220
Q

posterolateral buttock + posterior thigh + lateral leg +

A

L5 radiculopathy

221
Q

posterolateral buttock + posterior thigh + lateral leg posterior calf + lateral foot + diminished Ankle jerk

A

L5-S1 radiculopathy

222
Q

shooting radiating pain through the posterior thigh and posterior leg to little toe + anterior + posterior motor symptoms

A

Sciatica

223
Q

pain radiates through posterior buttock + posterior calf +
lateral foot + diminished Ankle jerk

A

S1 radiculopathy

224
Q

pain radiating to the hip + anterior thigh + medial aspect of knee + calf + diminished knee jerk

A

L4 radiculopathy

225
Q

Overweight adolescent + limping + hip stiffness + hip pain radiating to antero-medial thigh and knee

A

Slipped capital femoral epiphysis

226
Q

sudden onset of severe calf pain + limping + absent plantar reflex

A

Achilles tendon rupture

227
Q

Achilles tendon rupture investigation

A

Thompson Test
- absent plantar reflex

228
Q

prominent acromion + loss of deltoid contour + slightly abducted and externally rotated

A

anterior shoulder dislocation

229
Q

severe burning pain between the third and fourth toe + gets better walking barefoot + gets worse on weight bearing + localised tenderness

A

Morton Neuroma

230
Q

anterior shoulder dislocation nerve injury

A

Axillary nerve

231
Q

Mallet finger management

A

Maintain hyper-extension of the distal interphalangeal joint for 6-8 weeks

232
Q

Paget’s most common location

A

Pelvis 70%

233
Q

Slipped capital femoral epiphysis management

A

Percutaneous pin fixation

234
Q

bilateral leg pain + worse on erect posture + responds to exercise

A

Spinal stenosis

235
Q

Paget’s disease features

A

-Elevated alkaline phosphatase (early finding)
- bone pain (most common symptom)

236
Q

bone pain + tibia bowing + enlarged skull with frontal bossing

A

Paget’s disease

237
Q

genital pruritus + soreness + white wrinkled plaques

A

lichen sclerosus

238
Q

Lichen sclerosus

A

inflammatory condition of the skin.
Bimodal peak: prepubertal
girls, perimenopause.
Pruritus is the main symptom.
Main differential diagnosis is atrophic vaginitis.
First-line treatment includes steroids.
Lifelong surveillance with 6-monthly check-up is required due to the risk of squamous cell carcinoma of the skin

239
Q

Diagnosis of Lichen Planus

A

commonly occurs as pruritic, purple/pink, polygonal
papules and plaques on the skin of the extremities and trunk (cutaneous LP), but
lesions may also appear on the genitalia (genital LP) (genital LP) or oral mucosa (oral LP). The
lesions often have white, lacy markings known as Wickham striae and can form along the lines of minor trauma

Treatment includes topical high-potency glucocorticoids topical high-potency glucocorticoids (eg, betamethasone). The disorder is self-limited and typically resolves within 2 years.

240
Q

Atrophic vaginitis ddx

A
  • Candidiasis (topical antifungal)
  • Lichen Sclerosis (very potent topical corticosteroids)
241
Q

Testosterone cream uses

A
  • Lichen sclerosis
  • vaginal dryness
  • vulvar atrophy
  • post menopause
242
Q

Treatment of Lichen- sclerosis

A
  • 4% risk of SCC
  • Clobetasol ( steroid)
  • Retinoids/UV Therapy
  • Calcineurin
  • Cyyclosporin, Methothrexate
  • Lifelong follow up with 6 monyh than yearly
243
Q

Lichen- Sclerosis dx

A
  • pre-pubertal and peri-menopausal women
    TRIAD: genital itching, soreness and white wrinkled plaques in the genital area
    -Dx: biopsy