Fatty Acids Flashcards
What are the two Essential Fatty Acids?What are the omega bonds?
a-Linolenic Acid (ALA), w-3
Linolenic Acid (LA), w-6
What the three important Fatty acids?
Arachidonic Acid (AA)
Eicosapentanenoic (EPA)
Docosahexaenoic (DHA)
What is the difference between Saturated and Unsaturated
Saturated Fatty Acids- contain only single bonds with maximum number of hydrogens
Unsaturated- have 1 double bond
Cerebrosides
Single Glucose or Galactose
- Important in the nerve cell myelin/enables fast and efficent conduction of nerve impulses
Sulfatides
Found mainly in the Brain, CNS, PNS, Cell Growth/Signaling
Globosides
Carbohydrate/N-Acetyl
Found in red blood cells, serum, liver, spleen
Gangliosides
Carbohydrate + NANA
Abundant in Nervous System
What GAGs are associated with Blood Types?
A- GalNAC
B-Galactose
AB- GalNAC + Galactose
O- No sugar residues
How are Eicosanoids produced?
Prefer w-6 AA pathway
What are the steps and inhibitions for the Eicosanoid Synthetic Pathway?
Phospholipid to Phospholipid A2 (inhibited by Prednisolone) to Arachidonic Acid can be move right towards Lipoxygenase or left to Cyclooxygenase (Inhibited by Ibprofen and Asprin)
PGD(2)
Location: CNS/Mast Cells/ Adipose
Action: Lowering Body Temp
PGE(1)
Purpose: Dilate Blood Vessels
PGE(2)
Purpose: Causes fever, inflammation
PGF(2a)
Purpose: Induce Labor
PGI(2)
Purpose: Inhibits platelet activation, vasodilaton, Bronchodilator
TX
Thromboxanes A:
Purpose: Facilitates platelet aggregation and vasoconstrictor
Chylomicrons
Dietary triglycerols (90%) and cholesterol
VLDL
Very- Low Density Lipoprotein
Enogenous triglycerols and cholesterol
IDL
Triacylglycerols and Cholesterol
intermediate Density Lipoproteins
LDL
Low-Density Lipoproteins
Cholesterol
HDL
High Density Lipoproteins
Phosholipid and Protein
Composition of Bile Salts
Glycine, Taurine, conjugated to create cholic acid
What are the two main Corticosteriods in the human body?
Mineralcorticoids:
- Created in Adrenal Cortex
- Aldosterone
Glucocorticoids:
- Created in the Adrenal Cortex
- Cortisol
- Released during starvation and other stress related
Explain the steps for Vitamin D Synthesis
- Cholesterol
- Goes to the Liver
- Transported to the Skin
- Exposed to Sunlight/UV
- Back to Liver, OH added
6, To Kidney, OH Added - Calcitrol created (Vitamin D)