Fatty Acids Flashcards
What are the two Essential Fatty Acids?What are the omega bonds?
a-Linolenic Acid (ALA), w-3
Linolenic Acid (LA), w-6
What the three important Fatty acids?
Arachidonic Acid (AA)
Eicosapentanenoic (EPA)
Docosahexaenoic (DHA)
What is the difference between Saturated and Unsaturated
Saturated Fatty Acids- contain only single bonds with maximum number of hydrogens
Unsaturated- have 1 double bond
Cerebrosides
Single Glucose or Galactose
- Important in the nerve cell myelin/enables fast and efficent conduction of nerve impulses
Sulfatides
Found mainly in the Brain, CNS, PNS, Cell Growth/Signaling
Globosides
Carbohydrate/N-Acetyl
Found in red blood cells, serum, liver, spleen
Gangliosides
Carbohydrate + NANA
Abundant in Nervous System
What GAGs are associated with Blood Types?
A- GalNAC
B-Galactose
AB- GalNAC + Galactose
O- No sugar residues
How are Eicosanoids produced?
Prefer w-6 AA pathway
What are the steps and inhibitions for the Eicosanoid Synthetic Pathway?
Phospholipid to Phospholipid A2 (inhibited by Prednisolone) to Arachidonic Acid can be move right towards Lipoxygenase or left to Cyclooxygenase (Inhibited by Ibprofen and Asprin)
PGD(2)
Location: CNS/Mast Cells/ Adipose
Action: Lowering Body Temp
PGE(1)
Purpose: Dilate Blood Vessels
PGE(2)
Purpose: Causes fever, inflammation
PGF(2a)
Purpose: Induce Labor
PGI(2)
Purpose: Inhibits platelet activation, vasodilaton, Bronchodilator