Fatty Acids Flashcards

1
Q

What are the two Essential Fatty Acids?What are the omega bonds?

A

a-Linolenic Acid (ALA), w-3

Linolenic Acid (LA), w-6

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2
Q

What the three important Fatty acids?

A

Arachidonic Acid (AA)
Eicosapentanenoic (EPA)
Docosahexaenoic (DHA)

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3
Q

What is the difference between Saturated and Unsaturated

A

Saturated Fatty Acids- contain only single bonds with maximum number of hydrogens

Unsaturated- have 1 double bond

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4
Q

Cerebrosides

A

Single Glucose or Galactose

- Important in the nerve cell myelin/enables fast and efficent conduction of nerve impulses

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5
Q

Sulfatides

A

Found mainly in the Brain, CNS, PNS, Cell Growth/Signaling

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6
Q

Globosides

A

Carbohydrate/N-Acetyl

Found in red blood cells, serum, liver, spleen

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7
Q

Gangliosides

A

Carbohydrate + NANA

Abundant in Nervous System

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8
Q

What GAGs are associated with Blood Types?

A

A- GalNAC
B-Galactose
AB- GalNAC + Galactose
O- No sugar residues

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9
Q

How are Eicosanoids produced?

A

Prefer w-6 AA pathway

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10
Q

What are the steps and inhibitions for the Eicosanoid Synthetic Pathway?

A

Phospholipid to Phospholipid A2 (inhibited by Prednisolone) to Arachidonic Acid can be move right towards Lipoxygenase or left to Cyclooxygenase (Inhibited by Ibprofen and Asprin)

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11
Q

PGD(2)

A

Location: CNS/Mast Cells/ Adipose
Action: Lowering Body Temp

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12
Q

PGE(1)

A

Purpose: Dilate Blood Vessels

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13
Q

PGE(2)

A

Purpose: Causes fever, inflammation

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14
Q

PGF(2a)

A

Purpose: Induce Labor

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15
Q

PGI(2)

A

Purpose: Inhibits platelet activation, vasodilaton, Bronchodilator

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16
Q

TX

A

Thromboxanes A:

Purpose: Facilitates platelet aggregation and vasoconstrictor

17
Q

Chylomicrons

A
Dietary triglycerols (90%)
and cholesterol
18
Q

VLDL

A

Very- Low Density Lipoprotein

Enogenous triglycerols and cholesterol

19
Q

IDL

A

Triacylglycerols and Cholesterol

intermediate Density Lipoproteins

20
Q

LDL

A

Low-Density Lipoproteins

Cholesterol

21
Q

HDL

A

High Density Lipoproteins

Phosholipid and Protein

22
Q

Composition of Bile Salts

A

Glycine, Taurine, conjugated to create cholic acid

23
Q

What are the two main Corticosteriods in the human body?

A

Mineralcorticoids:

  • Created in Adrenal Cortex
  • Aldosterone

Glucocorticoids:

  • Created in the Adrenal Cortex
  • Cortisol
  • Released during starvation and other stress related
24
Q

Explain the steps for Vitamin D Synthesis

A
  1. Cholesterol
  2. Goes to the Liver
  3. Transported to the Skin
  4. Exposed to Sunlight/UV
  5. Back to Liver, OH added
    6, To Kidney, OH Added
  6. Calcitrol created (Vitamin D)