Fat Metabolism During Exercise Flashcards
1
Q
In basic terms, what conversion defines beta oxidation?
A
Conversion of fatty acyl-CoA to acetyl-CoA
2
Q
What is ‘lipolysis’?
A
The break down of triglycerides in skeletal muscle and adipose tissue.
3
Q
What are the 2 key lipases?
A
Adipose tissue triglycerides (ATGL) - predominantly breaks down triglycerides
Hormone sensitive lipase (HSL) - predominantly breaks down diglycerides
4
Q
How is adipose tissue lipolysis mediated?
A
Via ATGL and HSL
5
Q
What is an important activator of lipases?
A
Sympathetic nervous system circulating adrenaline acting through beta receptors.
6
Q
What is a negative effect of beta blockers?
A
An inhibition of mobilization of FA during exercise, associated with muscle fatigue due to increase in glycogen use.
7
Q
A
