ATP, ATP resynthesis and metabolic fuel utilisation Flashcards
1
Q
What molecule in the plasma membrane transports glucose from blood circulation to the muscle cell?
A
GLUT4
2
Q
What does carnitine do?
A
Aids in the transportation of long-chain fatty acids into mitochondria for beta oxidation.
3
Q
Carnitine is derived from diet or biosynthesized… what 2 molecules is carnitine biosynthesized from?
A
Lysine and methionine.
4
Q
Why is carnitine required?
A
Because mitochondrial membrane is impermeable to long-chain FAs (only medium and short chains can pass through).
5
Q
What are 3 ATP dependent processes in skeletal muscle?
A
1) Cross-bridge cycling (myosin ATPase)
2) Sarcolemmal excitability (NA+/K+ ATPase)
3) Calcium pumping into SR (SERCA - Ca2+ ATPase)
