Fat Flashcards
What are the products of fat oxidation?
CO2 + H2O + ATP
What type of fat is responsible for heat generation?
brown fat
BMI calculation?
BMI = weight (lbs) x 703 / height (inches)
T or F: BMI increases w/ age?
TRUE
BMI > 30 is considered?
Obese
BMI 25-29.5 is considered?
Overweight
BMI 18.5-24.9 is considered
healthy lean
BMI < 18.5 is considered?
Underweight
Dyslipidemia/hypderlipidemia can lead to what BMI classification?
Obese
What are the 3 types of adipocytes?
White, brown, beige
What are the 2 fat depots?
WAT BAT
BAT is greatest in what age range?
Infancy Decreases w/ age
Cold temperatures stimulate TSH to release T3/4 or epinephrine to produce heat?
Cold → TSH → T4/3 → UCP1 (uncoupling protein-1) → mitochondria → + FA = heat production
How does stress lead to heat production?
Stress → Epinephrine → G-protein 2nd msgr → TG breakdown to FA → mitochondria → + UCP1 = heat production
Does TSH & T3/T4 or Epinephrine allow for the direct transfer of food energy into heat energy?
TSH & T3/T4
T3, Epi, cold, hepativ bile acids, ANP, BNP and irisin (skeletal muscle hormone) stimulates what adipocyte?
Beige
What hormone promotes fuel storage and stimulates antilipolytics effect? ↑ LPL → converts TG to FA ↑ GLUT 4 → ↑ glucose uptake in adipocytes Inhibits hormone sensitive lipase (HSL)
Insulin
What hormones stimulate the lipolytic effect? (4)
- Epi (via HSL and adipose tissue triglyceride lipase (ATGL)) 2. Cortisol 3. Glucagon 4. GH
What hormone does not regulate fuel metabolites due to slow onset to adjust blood levels of nutrients?
Thyroid hormone
Does the subQ depot or visceral depot provide FA for energey during exercise?
subQ depot
Do women have higher subQ depots or visceral depots?
subQ due to higher whole body insulin sensitivity (gynecoid adiposity)
Do women have higher or lower whole body sensitivity to insulin?
Higher (gynecoid adiposity)