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Farma 1 > Farmacos del SNC > Flashcards

Farmacos del SNC Flashcards

Pinche bambi

1
Q

Ejemplos de neurotransmision retrograda

A

Endocanabinoides y No

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2
Q

Disfucion del sistema serotoninergico se asocia a

A

Depresion, ansiedad, agresividad e impulsividad

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3
Q

Principla via metabolica del sistema serotonnergico

A

MAO-A

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4
Q

Tipo de receptores del sistema serotonnergico

A 
Proteina G(5HT1, 5HT2, 5H4-7)
Ionicos (5HT3)
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5
Q

Tipo de receptores del sistema dopaminergico

A

Proteina G (D1 - D5)

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6
Q

sistema dopaminergico es metabolizada por:

A

MAO- B

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7
Q

sistema dopaminergico regula :

A

Recompensa, emocion, memoria, actividad motora y conocimiento

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8
Q

sistema dopaminergico, area mesolimbica;

A

Recompensa.

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9
Q

sistema dopaminergico, area Mesocortical:

A

Recompensa, emocion y control de impulsos.

Disfuncion: TDAH

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10
Q

sistema dopaminergico, area Mesoestriada:

A

Movimiento.

disfuncion: Parkinson y discinesia tardia

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11
Q

sistema dopaminergico, tuberoinfundiblar:

A

PRL

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12
Q

Sistema GABAergico

A

Poderosa fx inhibitoria del SNC

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13
Q

Sistema GABAergico metabolizado por:

A

GABA- T

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14
Q

Sistema GABAergico interviene en fx:

A

Sensitivo- motriz, vigilia, atencion y memoria

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15
Q

Principal inhibidor en tallo cerebral y medula espinal

A

Glicina

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16
Q

Coagonista de los receptores NMDA

A

Glicina

17
Q

Para ka activacion de los NMDA, deben estar presentes:

A

Glutamato
Glicina
Mg

18
Q

Potente excitador del SNC, sintetizado a partir del alfacetoglutarato o de glutamina

A

Glutamato

19
Q

Receptores del sistema glutamaergico

A

NMDA
AMPA
KA (kainato)
Metabotropos (1, 2, 3)

20
Q

Altas concentraciones de glutamato desencadenan:

A

Muerte neuronal (excitotoxicidad)

21
Q

Se encargan de la neurotransmision excitadora rapida en sistema glutamaergico

A

AMPA y Kainato

22
Q

Inducen potenciacion o depresion a LARGO PLAZO, en sistema glutamaergico

A

Receptores NMDA

23
Q

LTP

A

Potenciacion a largo plazo

24
Q

LTD

A

Depresion a largo plazo

25
Q

La actividad patologica del glutamato puede resultar en :

A

Focos epilepticos y muerte neuronal

26
Q

La mayor parte de las neuronas que sintetizan histaminas se localizan en:

A

Hipocampo

27
Q

Los R H1 se localizan en:

A

Neuroglia
Neuronas
Vasos

28
Q

Los RH3 se localizan en :

A

Ganglios basales y regiones olfativas del cerebro

Farma 1 (9 decks)

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