FA Pathology: Tumor Suppressor Genes Flashcards by Kara Heuvelhorst | Brainscape

Q

gene: p53

A

Li Fraumeni Syndrome; most human cancers

Transcription factor for p21, blocks G1-> S phase

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Q

p16

A

melanoma

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Q

APC

A

colorectal cancer (associated with FAP)

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Q

WT1

A

Wilm’s Tumor (nephroblastoma)

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Q

NF1

A

Neurofibromatosis type 1

RAS GTPase activating protein (RAS-GAP)

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Q

NF2

A

Neurofribromatosis type 2

Mertin (schwannomin protein)

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Q

DPC4

A

Pancreatic Cancer

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Q

DCC

A

Colon Cancer

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