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First Aid > FA Pathology: Oncogenes > Flashcards

FA Pathology: Oncogenes Flashcards

1
Q

abl

A

CML

Tyrosine Kinase

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2
Q

c-myc

A

Burkitt’s Lymphoma

Transcription factor

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3
Q

bcl-2

A

Follicular and undifferentiated lymphomas (inhibits apoptosis)

(Anti-apoptotic molecule)

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4
Q

HER2/neu (c-erbB2)

A

Breast, ovarian, and gastric carcinomas

Tyrosine Kinase

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5
Q

ras

A

Colon Carcinoma

GTPase

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6
Q

L-myc

A

Lung Tumor

Transcription Factor

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7
Q

N-myc

A

Neuroblastoma

Transcription Factor

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8
Q

ret

A

multiple endocrine neoplasia
(MEN) Types 2A and 2B
(Tyrosine Kinase)

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9
Q

c-kit

A

Gastrointestinal stromal tumor (GIST)

cytokine receptor

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First Aid (10 decks)

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