Extinction, Amygdala, and Prefrontal Cortex Flashcards
What is the function of the Primary Motor Cortex?
Control digits and face
What si the function of the supplementary motor area and premotor area?
planning voluntary movements
What is the function of the frontal eye fields?
Control eye movements
What is the function of the prefrontal cortex?
Association areas, info from more than one cortical area diverge, multimotom
What is the cytoarchitecture of the prefrontal cortex?
No prominent layer 4
prominent later 2 and 3
What are the inputs to the prefrontal cortex?
major subcortical input vie dorsomedial thalamus
Supplementary and premotor cortex
posterior parietal cortexm
What does the prefrontal cortex do?
Personality, Motivation, affect, executive function
What area of the rat brain deals with working memory?
Prelimbic or dorsal medial
What area of the rat brain deals with FC extinction?
Infralimbic or ventral medial
What pathway involves extinction?
ventral medial
What pathway involves context?
Entorhinal hippocampal cortex
What pathway involves habit?
Caudate accumbens
What is spontaneous recovery?
return of the fear with the passage of time since extinction
What is reinstatement?
Return of CR following exposure to original US or stressor
What is Renewal?
return of CR following exposure to context on which fear learning occurred or exposure to CS in new context
What do Lesions of the IL cortex do?
They impair the retrieval of extinction
What does neuronal activity in the vmPFC correlate with?
retrieval of extinction
What happens when stimulation of the vmPFC is paired with the CS?
it mimics the extinction memory
rats remember it better
What is a DREADD?
chemogeneitc manipulation, designer receptors that exclusively activated by designer drugs
What happens when the vmPFC is excited?
They excite GABAergic interneurons which inhibit the CeA output
