Extinction, Amygdala, and Prefrontal Cortex Flashcards

1
Q

What is the function of the Primary Motor Cortex?

A

Control digits and face

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2
Q

What si the function of the supplementary motor area and premotor area?

A

planning voluntary movements

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3
Q

What is the function of the frontal eye fields?

A

Control eye movements

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4
Q

What is the function of the prefrontal cortex?

A

Association areas, info from more than one cortical area diverge, multimotom

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5
Q

What is the cytoarchitecture of the prefrontal cortex?

A

No prominent layer 4
prominent later 2 and 3

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6
Q

What are the inputs to the prefrontal cortex?

A

major subcortical input vie dorsomedial thalamus
Supplementary and premotor cortex
posterior parietal cortexm

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7
Q

What does the prefrontal cortex do?

A

Personality, Motivation, affect, executive function

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8
Q

What area of the rat brain deals with working memory?

A

Prelimbic or dorsal medial

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9
Q

What area of the rat brain deals with FC extinction?

A

Infralimbic or ventral medial

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10
Q

What pathway involves extinction?

A

ventral medial

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11
Q

What pathway involves context?

A

Entorhinal hippocampal cortex

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12
Q

What pathway involves habit?

A

Caudate accumbens

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13
Q

What is spontaneous recovery?

A

return of the fear with the passage of time since extinction

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14
Q

What is reinstatement?

A

Return of CR following exposure to original US or stressor

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15
Q

What is Renewal?

A

return of CR following exposure to context on which fear learning occurred or exposure to CS in new context

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16
Q

What do Lesions of the IL cortex do?

A

They impair the retrieval of extinction

17
Q

What does neuronal activity in the vmPFC correlate with?

A

retrieval of extinction

18
Q

What happens when stimulation of the vmPFC is paired with the CS?

A

it mimics the extinction memory
rats remember it better

19
Q

What is a DREADD?

A

chemogeneitc manipulation, designer receptors that exclusively activated by designer drugs

20
Q

What happens when the vmPFC is excited?

A

They excite GABAergic interneurons which inhibit the CeA output