External Brain Morphology Flashcards

1
Q

Describe the thalamus

A

Large number of individual nuclei, each with a specific function

Major function is to relay information to the cortex via projections from these nuclei

Almost* all information destined for the cortex must go through the thalamus

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2
Q

Describe the hypothalamus

A

Large number of individual nuclei, each with a specific function

Functions as a CNS center for the regulation of autonomic and endocrine activity

Maintains internal homeostasis; involved in limbic system

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3
Q

What is the tectum?

A

Area dorsal to the cerebral aqueduct of Sylvius

Superior and inferior colliculi are involved in visual and auditory reflexes respectively

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4
Q

What is the pineal gland?

A

A midline structure lying above the superior colliculi

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5
Q

What is the clinical significance of lesions in the supratentorial space or pineal gland?

A

Can press on the tectum and close off the cerebral aqueduct

Causing non-communicating hydrocephalus

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6
Q

What is the tegmentum?

A

Area extending ventrally from the aqueduct to the substantia nigra

Contains Oculomotor nerve complex, trochlear nucleus/nerve, and red nucleus

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7
Q

What does the basal portion of the tegmentum consist of?

A

Substantia nigra - motor system

Crus cerebri - Descending pathways course through this structure

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8
Q

What is the function of the cerebellum?

A

Roles in balance, equilibrium, muscle tone, coordination and on-going movement etc.

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9
Q

What does each hemisphere of the cerebellum consist of?

A

A cortex (with folia and fissures)

Underlying white matter

Deep nuclei

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10
Q

What is the midline area of the cerebellum called?

A

Vermis

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11
Q

What are the three lobes of the cerebellum?

A

Anterior lobe - receives afferent input from spinal cord

Flocculonodular lobe - input from the vestibular system

Posterior lobe - input from cerebral cortex, voluntary movement coordination

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12
Q

What is the pons?

A

Bridges the brain to the cerebellum - receives input from the cortex via the CST and projects to the cerebellum

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13
Q

What can the pons be subdivided into?

A

Dorsal tegmental zone - contains CN V, VI, and VII nuclei

Ventral/basal zone - containing pontine nuclei and CST fibers

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14
Q

Describe the medulla

A

Both ascending and descending pathways pass through

Contains vital respiratory and cardiovascular centers

CN IX, X, XI, XII nuclei are located here

Clinical note* tonsilar herniation presses on the medulla

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15
Q

What lies just below the optic nerve? (inferior brain view)

A

Median eminence of hypothalamus

Infundibulum

Mamillary bodies

Cerebral peduncle

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16
Q

What are the lobes of the cerebral cortex and what are the sulci that divide them?

A

Frontal, Temporal, Parietal, Occipital

Lateral sulcus (sylvian)

Central sulcus (Rolandic)

17
Q

What are the three types of functional areas of the cerebral cortex?

A

Primary sensory/motor

Secondary, supplementary or “higher order” sensory/motor

Association areas - highest order, involved in integration of information

18
Q

What are the structural divisions of the cortex?

A

Neo-cortex - most of the human brain

Allocortex - consists of paleo- and archi-cortex

Transition cortex

19
Q

What is Brodmann’s Area 4?

A

Precentral gyrus - primary motor cortex

Somatotopically organized - areas with the finest motor movement have the largest representation in the cortex

20
Q

What is Brodmann’s Area 6?

A

Consists of supplementary and premotor areas

Contributes to the CST

21
Q

What is Brodmann’s Area 8?

A

Controls conjugate eye movements to the contralateral side

Lesion causes both eyes to deviate to the side of the lesion

22
Q

What are Brodmann’s Areas 44 and 45?

A

Aka Broca’s area - critically involved in the motor production of language

Broca’s aphasia- caused by damage to this part of the brain

Left hemisphere is uniquely organized to process language

23
Q

What is the prefrontal association cortex?

A

Parts of the superior, middle, and inferior frontal gyri - excluding areas 6 and 8

Plays multiple roles in cognitive behavior, especially executive functions like decision making and problem solving

24
Q

What is the limbic association cortex?

A

Consists of the orbitofrontal cortex and parts of the temporal lobe

Involved in personality and social behavior

25
What is the function of the temporal lobe areas of the limbic association cortex?
Learning and memory
26
What are the main sulci and gyri within the parietal lobe?
Pstcentral sulcus/postcentral gyrus Intraparietal sulcus Surpamarginal and angular gyri
27
What are Brodmann areas 1, 2, and 3?
Postcentral gyrus - primary somatosensory cortex Have four separate body representations where the different submodalities of sensation are kept separate
28
What separates the the superior parietal lobule and the inferior parietal lobule?
Intraparietal sulcus
29
What type of areas are parts of areas 2 and 5?
Higher order somatosensory areas Lesions in these areas produce somatosensory agnosias
30
What areas make up the posterior parietal cortex?
Areas 5 and 7 Play a major role in integrating visual and somatosensory information
31
What two important gyri/areas are located in the inferior parietal lobule and what is their function?
Supramarginal gyrus - area 40 Angular gyrus - area 39 In the dominant hemisphere these gyri are important for the perception and interpretation primarily of written language Lesions may cause alexia and agraphia
32
What are the main sulci/gyri located within the occipital lobe?
Calcarine cortex - made up of the cuneus and lingual gyri above and below the calcarine fissure respectively
33
What is area 17?
Calcarine cortex/primary visual cortex Visuotopically organized
34
What are areas 18 and 19?
Higher order visual orders Lesions can produce visual agnosias
35
How is the temporal lobe divided?
Superior and inferior temporal sulci divide the lobe into superior, middle, and inferior temporal gyri
36
What is area 41?
The primary auditory cortex on the transverse temporal gyri of Heschl Tonotopically organized to represent the basilar membrane - with disproportionate representation to sounds devoted to speech
37
Why don't unilateral lesions in the areas around the primary auditory cortex usually produce significant auditory agnosias?
There are many bilateral connections of auditory structures below the cortex Instead, there will just be bilateral diminuation with greater loss contralateral
38
What is Wernicke's area?
Posterior part of the superior temporal gyrus (part of area 22) in the dominant hemisphere Necessary for the interpretation of spoken language
39
What is Wernicke's aphasia?
Lesions in Wernicke's area that cause the patient to be unable to understand spoken language Can speak fluently, but speak nonsense