Exfoliative Cytology Flashcards

1
Q

Fixation time for exfoliative cytology

A

15mins

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2
Q

Ideal fixation time for exfoliative cytology

A

60mins

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3
Q

Fixative for exfoliative cytology that gives best result but not commonly used

A

Equal parts of 95% ethanol and ether

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4
Q

Commonly used fixative for exfoliative cytology

A

95% ethanol

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5
Q

Fixative for sputum

A

Saccomano preservative

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6
Q

Nuclear stain in paps

A

Harris hematoxylin

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7
Q

Stain for paps with strong affinity for mature cells

A

Og6 stain

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8
Q

Stain for paps with strong affinity for immature cells

A

Ea50

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9
Q

Ideal for studying the hormonal status, evaluation of inflammatory conditions, classification of the normal flora and rarely detection of malignant vaginal lesions

A

Proximal third of the vaginal wall

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10
Q

Most common site for cancer screening
Use of ayre’s spatula
Histology: stratified squamous non keratinizing

A

Ectocervix

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11
Q

Site where most malignancies arise

A

Transformation zone

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12
Q

For detection of endocervical lesions, intrauterine lesions

Histology: simple columnar epithelium

A

Endocervix

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13
Q

Material for endocervical canal

A

Endocervical brush

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14
Q

Material for patients with hysterectomy

A

Vaginal scrape

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15
Q

Material for hormonal cytology

A

Lateral vaginal scrape

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16
Q

Material for localization of vaginal adenosis

A

Four quadrant vaginal scrape

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17
Q

Material for detection of herepetic lesions or carcinoma

A

Vulvar scrape

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18
Q

Equipment for vaginal aspiration

6-8 inches x 1/4 inches

A

Glass pipet and rubber bulb

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19
Q

Equipment for swab smear

A

Ayre’s spatula

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20
Q

Equipment for endocervical or endometrial aspiration

A

Laryngeal cannula attached to a 10cc syringe

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21
Q

Produced by proliferating granulose theca cells of the ovarian follicles
Acts upon the superficial cells

A

Estrogen

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22
Q

Produced by corpus luteum formed after ovulation

Acts upon the intermediate cells

A

Progesterone

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23
Q

Boat shaped intermediate cells with a strong tendency to fold and curl their edges

A

Navicular cells

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24
Q

More commonly seen in pregnant women

Appearance: double cell wall appearance

A

Pregnancy cells

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25
Appearance: sunny side up or fried egg
Parabasal cells
26
Chmi ratio
Parabasals:intermediates:superficials
27
Shift to right chmi ratio | Seen among menopausal women taking estrogen
0/10/90
28
Chmi ratio of pregnant women | Progesterone is involved
0/70/30
29
Chmi ratio of premenarche (females who haven’t undergo menstruation) and post menopausal
100/0/0
30
Pregnant women chmi ratio
0/100/0
31
Cell that denotes specimen adequacy
Endocervical cells
32
Shish kebab appearance in paps smear
Candida albicans
33
Presence of clue cells or moth eaten appearance
Gardnerella vaginalis
34
Squamous epithelial cells that show cytopathic effects of hpv
Koilocytes
35
Hsv cytopathic effect is characterized as macrosomia, multinucleation, nuclear molding and ground glass chromatin pattern
Cowdry type a
36
Malignant cell of epithelial origin
Carcinomas
37
Most common form of cervical malignancy
Invasive squamous cell carcinoma
38
Presence of _______________ indicates satisfactory sputum collection
Alveolar macrophage
39
Packaging center of a eukaryotic cell
Golgi apparatus
40
Bowman’s capsule, endothelium, loop of henle, lung alveoli histology
Simple squamous
41
Ducts of glands, walls of thyroid follicles, kidney tubules histology
Simple cuboidal
42
Gall bladder (non ciliated), uterine tube (ciliated) histology
Simple columnar
43
Skin (keratinized), vagina, esophagus, cervix histology
Stratified squamous
44
Ducts of sweat glands histology
Stratified cuboidal
45
Male urethra histology
Stratified columnar
46
Urinary bladder histology
Transitional
47
Trachea (ciliated w/ goblet cells), epididymis histology
Pseudostratified columnar
48
Increase in the size of cells
Hypertrophy
49
Absolute increase of cell number
Hyperplasia
50
Aka atypical hyperplasia | Pre neoplastic
Dysplasia
51
Autolysis or heterolysis Liquefied Complete destruction of cells Ex cerebral infarct
Liquefactive necrosis
52
Cheesy and white appearance | Usually seen in tb tularemia lgv
Caseous necrosis
53
Description of focal areas of fat destruction due to release of pancreatic lipases Chalky white appearance due to released fatty acids and calcium Ex pancreatitis
Fat necrosis
54
Rubbery clot
Post mortem clot
55
Most reliable feature of malignancy
Metastasis
56
Most common pathway for carcinomas
Lymphatic spread
57
Most common pathway for sarcomas
Hematogenous spread
58
Score based upon the size and or extent of invasion
T
59
Score indicates the extent of lymph node involvement
N
60
Score indicates whether distant metastases are present
M
61
Complete removal of the lesion | Most reliable biopsy
Excisional biopsy
62
Organs are removed one by one | Widely used
Virchow’s technique
63
In situ dissection | En bloc
Rokitansky’s technique
64
En bloc
Ghon’s technique
65
En masse
Letulle’s technique
66
Clinical pathology lab reports retention
Two years
67
Autopsy forensic reports and slides retention
Indefinite
68
Surgical pathology reports and pathology tissue block retention
Ten years
69
Cytogenetic reports retention
Twenty years
70
Serum or body fluids retention | Surgical pathology and cytology turn around time
Two days
71
Frozen sections turn around time
5-15mins
72
Autopsy report turn around time
Seven days